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Metabolomics in nutrition research - A powerful window into nutritional metabolism

Lookup NU author(s): Professor Lorraine Brennan

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Abstract

© 2016 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society. Metabolomics is the study of smallmolecules present in biological samples. In recent years it has become evident that such small molecules, called metabolites, play a key role in the development of disease states. Furthermore, metabolomic applications can reveal information about alterations in certain metabolic pathways under different conditions. Data acquisition in metabolomics is usually performed using nuclear magnetic resonance (NMR)-based approaches or mass spectrometry (MS)-based approaches with a more recent trend including the application of multiple platforms in order to maximise the coverage in terms of metabolites measured. The application ofmetabolomics is rapidly increasing and the present review will highlight applications in nutrition research.


Publication metadata

Author(s): Brennan L

Publication type: Article

Publication status: Published

Journal: Essays in Biochemistry

Year: 2016

Volume: 60

Issue: 5

Pages: 451-458

Online publication date: 15/12/2016

Acceptance date: 29/10/2016

ISSN (print): 0071-1365

Publisher: Portland Press Ltd.

URL: http://doi.org/10.1042/EBC20160029

DOI: 10.1042/EBC20160029


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