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Lookup NU author(s): Dr Emily Mavin,
Dr Xiao WangORCiD,
Professor Anne Dickinson
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© 2017 Ghimire, Weber, Mavin, Wang, Dickinson and Holler. For over 60 years, hematopoietic stem cell transplantation has been the major curative therapy for several hematological and genetic disorders, but its efficacy is limited by the secondary disease called graft versus host disease (GvHD). Huge advances have been made in successful transplantation in order to improve patient quality of life, and yet, complete success is hard to achieve. This review assimilates recent updates on pathophysiology of GvHD, prophylaxis and treatment of GvHD-related complications, and advances in the potential treatment of GvHD.
Author(s): Ghimire S, Weber D, Mavin E, Wang XN, Dickinson AM, Holler E
Publication type: Review
Publication status: Published
Journal: Frontiers in Immunology
Online publication date: 20/03/2017
Acceptance date: 17/01/2017
ISSN (electronic): 1664-3224
Publisher: Frontiers Research Foundation