Lookup NU author(s): Dr Vicky Brocklebank,
Dr Katrina Wood,
Professor David Kavanagh
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© 2018 by the American Society of Nephrology. Thrombotic microangiopathy can manifest in a diverse range of diseases and is characterized by thrombocytopenia, microangiopathic hemolytic anemia, and organ injury, including AKI. It can be associated with significant morbidity and mortality, but a systematic approach to investigation and prompt initiation of supportive management and, in some cases, effective specific treatment can result in good outcomes. This review considers the classification, pathology, epidemiology, characteristics, and pathogenesis of the thrombotic microangiopathies, and outlines a pragmatic approach to diagnosis and management.
Author(s): Brocklebank V, Wood KM, Kavanagh D
Publication type: Article
Publication status: Published
Journal: Clinical Journal of the American Society of Nephrology
Print publication date: 07/02/2018
Online publication date: 01/10/2017
Acceptance date: 29/09/2017
ISSN (print): 1555-9041
ISSN (electronic): 1555-905X
Publisher: American Society of Nephrology
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