Toggle Main Menu Toggle Search

Open Access padlockePrints


Lookup NU author(s): Professor Johannes Attems


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


© 2014 Elsevier Inc. All rights reserved. Amyloidosis refers to a heterogeneous group of disorders (systemic or localized) characterized by the extracellular deposition of insoluble fibrils in different tissues and organs leading to cellular damage and organ dysfunction. Twenty-four different proteins can form amyloid structures. In the human brain, the most frequent one is the amyloid-. β protein that is associated with Alzheimer's disease; other cerebral amyloidoses may be related to prions, cystatin C, transthyretin, gelsolin, ABri, and ADan. The main neuropathological lesions caused by cerebral amyloidosis are cerebral amyloid angiopathy and amyloid plaques.

Publication metadata

Author(s): Attems J, Thal DR

Publication type: Book Chapter

Publication status: Published

Book Title: Encyclopedia of the Neurological Sciences

Year: 2014

Pages: 158-164

Online publication date: 01/04/2014

Acceptance date: 01/04/2014

Edition: 2nd

Publisher: Elsevier Inc.


DOI: 10.1016/B978-0-12-385157-4.00581-9

Library holdings: Search Newcastle University Library for this item

ISBN: 9780123851574