Publications by Professor Johannes Attems - ePrints

Browsing publications by Professor Johannes Attems.

Newcastle Authors	Title	Year
Dr Calum Hamilton Professor Fiona Matthews Professor Johannes Attems Dr Paul Donaghy Dr Daniel Erskine et al.	Associations between multimorbidity and neuropathology in dementia: a case for considering functional cognitive disorders, psychiatric illness, and dementia mimics	2024
Dr Lauren Walker Professor Johannes Attems	Prevalence of Concomitant Pathologies in Parkinson's Disease: Implications for Prognosis, Diagnosis, and Insights into Common Pathogenic Mechanisms	2024
Dr Lauren Walker Professor Alan Thomas Professor Johannes Attems	Prevalence, distribution, and severity of cerebral amyloid angiopathy differ between Lewy body diseases and Alzheimer’s disease	2024
Jessica Katanga Dr Calum Hamilton Dr Lauren Walker Professor Johannes Attems Professor Alan Thomas et al.	Age-related hearing loss and dementia-related neuropathology: An analysis of the United Kingdom brains for dementia research cohort	2023
Professor Tiago Outeiro Professor Johannes Attems Professor Ian McKeith	Defining the Riddle in Order to Solve It: There Is More Than One “Parkinson's Disease”	2023
Professor Johannes Attems	Dopamine and vesicular monoamine transport loss supports incidental Lewy body disease as preclinical idiopathic Parkinson	2023
Professor Johannes Attems Kirsty McAleese	LATE-NC staging in routine neuropathologic diagnosis: an update	2023
Professor Carol Brayne Professor Johannes Attems Professor Fiona Matthews Dr Tuomo Polvikoski	Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts	2022
Professor Johannes Attems	Genome-wide association study and functional validation implicates JADE1 in tauopathy	2022
Professor Johannes Attems	Interpretable deep learning of myelin histopathology in age-related cognitive impairment	2022
Professor Johannes Attems	Mitochondrial dysfunction is a key pathological driver of early stage Parkinson's	2022
Dr David Koss Dr Daniel Erskine Dr Andrew Porter Dr Pawel Palmowski Professor Johannes Attems et al.	Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies.	2022
Chris Hatton Dr David Koss Dr Lauren Walker Professor Tiago Outeiro Professor Johannes Attems et al.	Prion-like α-synuclein pathology in the brain of infants with Krabbe disease	2022
Dr Daniel Erskine Professor Johannes Attems Professor Ian McKeith Professor Tiago Outeiro	α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity	2022
Professor Johannes Attems	123I FP-CIT SPECT in dementia with Lewy bodies, Parkinson's disease and Alzheimer's disease: a new quantitative analysis of autopsy confirmed cases	2021
Professor Johannes Attems	Discovery of autism/intellectual disability somatic mutations in Alzheimer's brains: mutated ADNP cytoskeletal impairments and repair as a case study	2021
Professor Johannes Attems	Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy	2021
Dr Kirsty McAleese Mohi Miah Dr Lauren Walker Mary Johnson Dr Sean Colloby et al.	Frontal white matter lesions in Alzheimer’s disease are associated with both small vessel disease and AD-associated cortical pathology	2021
Professor Johannes Attems Professor Alan Thomas	Genetic risk for Alzheimer's disease influences neuropathology via multiple biological pathways	2021
Dr Daniel Erskine Professor Johannes Attems	Insights into Lewy body disease from rare neurometabolic disorders	2021
Dr Daniel Erskine Dr David Koss Dr Viktor Korolchuk Professor Tiago Outeiro Professor Johannes Attems et al.	Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders	2021
Dr Calum Hamilton Professor Fiona Matthews Dr Daniel Erskine Professor Johannes Attems Professor Alan Thomas et al.	Neurodegenerative brain changes are associated with area deprivation in the United Kingdom: findings from the Brains for Dementia Research study	2021
Dr Marzena Kurzawa-Akanbi Dr Michael Keogh Eliona Tsefou Lynne Ramsay Mary Johnson et al.	Neuropathological and Biochemical Investigation of Hereditary Ferritinopathycases with Ferritin Light Chain Mutation: Prominent Protein Aggregation in the Absence of Major Mitochondrial or Oxidative Stress	2021
Professor Johannes Attems Dr Lauren Walker Dr Kirsty McAleese Dr Tuomo Polvikoski Professor Ian McKeith et al.	Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study	2021
Dr David Koss Odeta Bondarevaite Professor Johannes Attems Professor Tiago Outeiro	RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies	2021
Chris Hatton Dr Amy Reeve Dr Nichola Lax Dr Alasdair Blain Dr Yi Ng et al.	Complex I reductions in the nucleus basalis of Meynert in Lewy body dementia: the role of Lewy bodies	2020
Dr Kirsty McAleese Dr Lauren Walker Dr Daniel Erskine Mary Johnson Dr David Koss et al.	Concomitant LATE-NC in Alzheimer's disease is not associated with increased tau or amyloid-β pathological burden	2020
Professor Johannes Attems	Fulminant corticobasal degeneration: a distinct variant with predominant neuronal tau aggregates	2020
Dr Daniel Erskine Dr Christopher Morris Professor Johannes Attems	Investigating the Presence of Doubly‐phosphorylated α‐Synuclein at Tyrosine 125 and Serine 129 In Idiopathic Lewy Body Diseases	2020
Dr Daniel Erskine Dr Amy Reeve Dr Tuomo Polvikoski Dr Andrew Schaefer Professor Robert Taylor et al.	Lewy body pathology is more prevalent in older individuals with mitochondrial disease than controls	2020
Dr Kirsty McAleese Professor Johannes Attems Professor Alan Thomas	Neuropsychiatric symptoms in limbic-predominant age-related TDP-43 encephalopathy and Alzheimer's disease	2020
Mary Johnson Professor Johannes Attems	The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies	2020
Professor Johannes Attems	The Pattern of AQP4 Expression in the Ageing Human Brain and in Cerebral Amyloid Angiopathy	2020
Professor Johannes Attems	Vascular α1a adrenergic receptors as a potential therapeutic target for ipad in alzheimer’s disease	2020
Dr Lauren Walker Professor Johannes Attems	Clinical and neuropathological differences between Parkinson's disease, Parkinson's disease dementia and dementia with Lewy bodies – current issues and future directions	2019
Dr David Koss Mary Johnson Professor Johannes Attems Professor Tiago Outeiro	Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies	2019
Lina Patterson Professor Stephen Rushton Professor Johannes Attems Professor Alan Thomas Dr Christopher Morris et al.	Degeneration of dopaminergic circuitry influences depressive symptoms in Lewy body disorders	2019
Professor Tiago Outeiro Dr David Koss Dr Daniel Erskine Dr Lauren Walker Abishek Umashankar et al.	Dementia with Lewy bodies: an update and outlook	2019
Dr Kirsty McAleese Madhurima Dey Dr Lauren Walker Dr Daniel Erskine Mary Johnson et al.	Extravascular fibrinogen in the white matter of Alzheimer’s disease and normal aged brains: implications for fibrinogen as a biomarker for Alzheimer’s disease	2019
Dr Peter Kullar Dr Ian Wilson Professor Johannes Attems Dr Christopher Morris	Frequency and signature of somatic variants in 1461 human brain exomes	2019
Dr Christopher Morris Professor Johannes Attems Professor Tim Griffiths Professor Ian McKeith Professor Alan Thomas et al.	Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia	2019
Dr Christopher Morris Professor Johannes Attems Professor Tim Griffiths Professor Ian McKeith Professor Alan Thomas et al.	Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia	2019
Professor Johannes Attems Professor Carol Brayne	Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report	2019
Professor Johannes Attems Dr Dag Aarsland	Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration	2019
Dr Lauren Walker Dr Kirsty McAleese Dr Daniel Erskine Professor Johannes Attems	Neurodegenerative Diseases and Ageing	2019
Lina Patterson Dr Michael Firbank Dr Sean Colloby Professor Johannes Attems Professor Alan Thomas et al.	Neuropathological Changes in Dementia With Lewy Bodies and the Cingulate Island Sign	2019
Dr Thomas Meyer Professor Johannes Attems Professor Tiago Outeiro	Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein	2019
Dr Daniel Erskine Professor John-Paul Taylor Professor Alan Thomas Daniel Collerton Professor Ian McKeith et al.	Pathological Changes to the Subcortical Visual System and its Relationship to Visual Hallucinations in Dementia with Lewy Bodies	2019
Professor Nicola Pavese Professor Johannes Attems	Rare histotype of sporadic Creutzfeldt-Jakob disease, clinically suspected as corticobasal degeneration	2019
Professor Johannes Attems Professor Carol Brayne	Reply: LATE to the PART-y	2019
Professor Johannes Attems	The first year	2019
Dr James Lloyd Dr George Petrides Dr Paul Donaghy Dr Sean Colloby Professor Johannes Attems et al.	A new visual rating scale for Ioflupane imaging in Lewy body disease	2018
Dr Kirsty McAleese Dr Lauren Walker Dr Sean Colloby Professor John-Paul Taylor Professor Alan Thomas et al.	Cortical tau pathology: A major player in fibre-specific white matter reductions in Alzheimer's disease?	2018
Mary Johnson Dr Ahmad Khundakar Professor Johannes Attems	Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-β plaques: A potential role in shaping plaque pathology?	2018
Dr Lauren Walker Dr Jonathan Coxhead Dr Ian Wilson Dr Matthew Bashton Dr Christopher Morris et al.	High prevalence of focal and multi-focal somatic genetic variants in the human brain	2018
Professor Alan Thomas Dr Fariba Mahin-Babaei Dr Mohammad Saidi Debbie Lett Professor John-Paul Taylor et al.	Improving the identification of dementia with Lewy bodies in the context of an Alzheimer’s-type dementia	2018
Professor Johannes Attems Dr Kirsty McAleese Dr Lauren Walker	Methods for pathological classification of Alzheimer's disease	2018
Dr Daniel Erskine Professor Alan Thomas Dr Ahmad Khundakar Dr Peter Hanson Professor John-Paul Taylor et al.	Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies	2018
Professor Johannes Attems	Neuropathology and biochemistry of early onset familial Alzheimer’s disease caused by presenilin-1 missense mutation Thr116Asn	2018
Dr Michael Keogh Dr Wei Wei Dr Ian Wilson Professor Johannes Attems Dr Christopher Morris et al.	Oligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains	2018
Dr Bernadette Carroll Diego Manni Dr Rhoda Stefanatos Fiona Menzies Dr Graham Smith et al.	Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis	2018
Professor Johannes Attems	Phosphorylation of different tau sites during progression of Alzheimer's disease	2018
Professor Johannes Attems	Proteomics for synaptic markers of cognitive decline in neurodegenerative diseases	2018
Dr Daniel Erskine Lina Patterson Dr Athanasios Alexandris Dr Peter Hanson Professor Ian McKeith et al.	Regional levels of physiological α-synuclein are directly associated with Lewy body pathology	2018
Professor Johannes Attems	SIRT1, miR-132 and miR-212 link human longevity to Alzheimer's Disease	2018
Dr Christopher Morris Professor Johannes Attems	Somatic variants in autosomal dominant genes are a rare cause of sporadic Alzheimer's disease	2018
Professor Johannes Attems	Alzheimer's disease pathology in synucleinopathies	2017
Professor Alan Thomas Professor Johannes Attems Dr Sean Colloby Professor John O'Brien Professor Ian McKeith et al.	Author response: Autopsy validation of 123 I-FP-CIT dopaminergic neuroimaging for the diagnosis of DLB	2017
Professor Alan Thomas Professor Johannes Attems Dr Sean Colloby Professor John O'Brien Professor Ian McKeith et al.	Autopsy validation of ¹²³ I-FP-CIT dopaminergic neuroimaging for the diagnosis of DLB	2017
Professor Johannes Attems	Common Impact of Chronic Kidney Disease and Brain Microhemorrhages on Cerebral Aβ Pathology in SHRSP	2017
Professor Ian McKeith Professor John-Paul Taylor Dr Dag Aarsland Professor Johannes Attems Dr Clive Ballard et al.	Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium	2017
Dr Michael Keogh Dr Wei Wei Dr Ian Wilson Dr Jonathan Coxhead Dr Helen Griffin et al.	Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource	2017
Professor Johannes Attems	Interactions of pathological proteins in neurodegenerative diseases	2017
Dr Michael Keogh Dr Ian Wilson Dr Jonathan Coxhead Dr Helen Griffin Dr Marzena Kurzawa-Akanbi et al.	Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains	2017
Dr Daniel Erskine Professor Alan Thomas Professor John-Paul Taylor Michael Savage Professor Johannes Attems et al.	Neuronal Loss and Α-Synuclein Pathology in the Superior Colliculus and Its Relationship to Visual Hallucinations in Dementia with Lewy Bodies	2017
Dr Kirsty McAleese Dr Lauren Walker Mary Johnson Dr Daniel Erskine Dr Sean Colloby et al.	Parietal white matter lesions in Alzheimer's disease are associated with cortical neurodegenerative pathology, but not with small vessel disease	2017
Dr Lauren Walker Dr Kirsty McAleese Mary Johnson Dr Ahmad Khundakar Dr Daniel Erskine et al.	Quantitative neuropathology: an update on automated methodologies and implicationsfor large scale cohorts	2017
Olivia Skrobot Professor Johannes Attems Professor Raj Kalaria	Reply: Atherosclerosis and vascular cognitive impairment neuropathological guideline	2017
Dr Daniel Erskine Professor Alan Thomas Professor Johannes Attems Professor John-Paul Taylor Professor Ian McKeith et al.	Specific patterns of neuronal loss in the pulvinar nucleus in dementia with Lewy bodies	2017
Mary Johnson Professor Raj Kalaria Professor Johannes Attems	Systems proteomic analysis reveals that clusterin and tissue inhibitor of metalloproteinases 3 increase in leptomeningeal arteries affected by cerebral amyloid angiopathy	2017
Dr Kirsty McAleese Dr Lauren Walker Dr Daniel Erskine Professor Alan Thomas Professor Ian McKeith et al.	TDP-43 pathology in Alzheimer's disease, dementia with Lewy bodies and ageing	2017
Professor Johannes Attems	The multi-morbid old brain	2017
Professor Johannes Attems Richard Heale	Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy	2016
Professor Johannes Attems	An isoform-specific role of FynT tyrosine kinase in Alzheimer's disease	2016
Dr Ahmad Khundakar Dr Peter Hanson Dr Daniel Erskine Dr Nichola Lax Evangelia Karyka et al.	Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations	2016
Dr Francesco Vergani Dr Christopher Morris Professor Johannes Attems	Anatomic Connections of the Subgenual Cingulate Region	2016
Professor Johannes Attems	Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord	2016
Mary Johnson Professor Johannes Attems Professor John O'Brien Professor Alan Thomas	Decreased Levels of VAMP2 and Monomeric Alpha-Synuclein Correlate with Duration of Dementia	2016
Professor Johannes Attems	Dementia in Parkinson's disease is associated with enhanced mitochondrial complex I deficiency	2016
Professor Johannes Attems Professor Raj Kalaria	Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy	2016
Professor Johannes Attems	Erratum to: Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord (Brain Struct Funct, 10.1007/s00429-016-1191-3)	2016
Dr Michael Keogh Dr Marzena Kurzawa-Akanbi Dr Helen Griffin Dr Konstantinos Douroudis Dr Kristin Ayers et al.	Exome sequencing in dementia with Lewy bodies	2016
Debbie Lett Professor Johannes Attems Dr Christopher Morris	Extended post-mortem delay times should not be viewed as a deterrent to the scientific investigation of human brain tissue: a study from the Brains for Dementia Research Network Neuropathology Study Group, UK	2016
Dr Lauren Walker Professor Alan Thomas Debbie Lett Dr Kirsty McAleese Mary Johnson et al.	Investigating the pathological correlate of motor dysfunction in DLB and PDD	2016
Professor Johannes Attems	Is the time ripe for new diagnostic criteria of cognitive impairment due to cerebrovascular disease? Consensus report of the International Congress on Vascular Dementia working group	2016
Dr Kirsty McAleese Professor Raj Kalaria Professor Johannes Attems	Post-mortem assessment in vascular dementia: advances and aspirations	2016
Professor Johannes Attems	Proteomic characterization of neuromelanin granules isolated from human substantia nigra by laser-microdissection	2016
Professor Johannes Attems Dr Clive Ballard Dr Dag Aarsland	Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia	2016
Professor Johannes Attems	The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells	2016
Dr Kirsty McAleese Dr Lauren Walker Dr Daniel Erskine Professor Johannes Attems	The prevalence of TDP-43 pathology in Alzheimer's disease, Lewy body dementia and mixed Alzheimer's disease and Lewy body disease	2016
Professor Johannes Attems	Unfolded protein response is activated in Lewy body dementias	2016
Olivia Skrobot Professor Johannes Attems Professor Raj Kalaria	Vascular Cognitive Impairment Neuropathology Guidelines (VCING) - a UK multi-centre consensus study	2016
Olivia Skrobot Professor Johannes Attems Professor Raj Kalaria	Vascular cognitive impairment neuropathology guidelines (VCING): the contribution of cerebrovascular pathology to cognitive impairment	2016
Dr Stephen Jaiser Professor Johannes Attems Dr Timothy Williams	A case of facial onset sensory and motor neuronopathy (FOSMN) associated with TDP-43 proteinopathy	2015
Professor Johannes Attems	Challenges of multimorbidity of the aging brain: a critical update	2015
Dr Daniel Erskine Professor John-Paul Taylor Dr Michael Firbank Professor John O'Brien Professor Ian McKeith et al.	Changes to the lateral geniculate nucleus in Alzheimer's disease but not dementia with Lewy bodies	2015
Dr Pietro Tiraboschi Professor Johannes Attems Professor Alan Thomas Dr Evelyn Jaros Debbie Lett et al.	Clinicians' ability to diagnose dementia with Lewy bodies is not affected by β Normal 0 false false false EN-GB X-NONE X-NONE -amyloid load	2015
Dr Kirsty McAleese Dr Michael Firbank Madhurima Dey Dr Sean Colloby Dr Lauren Walker et al.	Cortical tau load is associated with white matter hyperintensities	2015
Dr Timothy Williams Dr Stephan Jaiser Professor Johannes Attems	Facial Onset Sensory and Motor Neuronopathy: Further Evidence for a TDP-43 Proteinopathy	2015
Dr Lauren Walker Professor Johannes Attems	Frontotemporal lobar degeneration FTLD-tau: preclinical lesions, vascular, and Alzheimer-related co-pathologies	2015
Professor Johannes Attems Professor Raj Kalaria	Global proteomic profiling of brain leptomeningeal arteries from patients with cerebral amyloid angiopathy reveals novel therapeutic targets	2015
Dr Lauren Walker Dr Kirsty McAleese Professor Alan Thomas Mary Johnson Dr Carmen Martin-Ruiz et al.	Neuropathologically mixed Alzheimer's and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes	2015
Professor Johannes Attems Dr Lauren Walker	Olfaction and Aging: A Mini-Review	2015
Professor Johannes Attems	PART, a distinct tauopathy, different from classical sporadic Alzheimer disease	2015
Professor Johannes Attems Professor John O'Brien Dr Dag Aarsland Dr Clive Ballard	Regional Multiple Pathology Scores Are Associated with Cognitive Decline in Lewy Body Dementias	2015
Professor Johannes Attems	Spreading pathologies precede cognitive decline in Alzheimer's disease	2015
Professor Carol Brayne Mary Johnson Emeritus Professor Elaine Perry Professor Johannes Attems Dr Clive Ballard et al.	Stage-Specific Changes in Neurogenic and Glial Markers in Alzheimer's Disease	2015
Dr Alison Spilsbury Dr Satomi Miwa Professor Johannes Attems Dr Gabriele Saretzki	The Role of Telomerase Protein TERT in Alzheimer's Disease and in Tau-Related Pathology In Vitro	2015
Professor Johannes Attems	A platelet protein biochip rapidly detects an Alzheimer’s disease-specific phenotype	2014
Professor Johannes Attems	Amyloidosis	2014
Mary Johnson Professor Johannes Attems Dr Clive Ballard Professor Alan Thomas Professor John O'Brien et al.	Assessment of ZnT3 and PSD95 protein levels in Lewy body dementias and Alzheimer's disease: association with cognitive impairment	2014
Dr Kirsty McAleese Madhurima Dey Dr Michael Firbank Shane McParland Professor John O'Brien et al.	Cortical neurodegenerative pathology has an influence on white matter integrity	2014
Professor Johannes Attems	Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue	2014
Mary Johnson Professor Johannes Attems Dr Clive Ballard Professor Alan Thomas Professor John O'Brien et al.	Dynamin1 concentration in the prefrontal cortex is associated with cognitive impairment in Lewy body dementia	2014
Dr Christopher Morris Professor Johannes Attems Professor Tim Griffiths Professor Ian McKeith Professor Alan Thomas et al.	Frontotemporal dementia and its subtypes: a genome-wide association study	2014
Professor Johannes Attems	High-level ERBB2 gene amplification is associated with a particularly short time-to-metastasis, but results in a high rate of complete response once trastuzumab-based therapy is offered in the metastatic setting	2014
Professor Johannes Attems	Interplay between age, cerebral small vessel disease, parenchymal amyloid-β, and tau pathology: Longitudinal studies in hypertensive stroke-prone rats	2014
Professor Raj Kalaria Professor Johannes Attems	Microvascular Pathology	2014
Mary Johnson Emeritus Professor Elaine Perry Professor Johannes Attems	Neurogenic marker alterations in the hippocampus in relation to cholinergic therapy in Lewy Body dementia	2014
Professor Johannes Attems Dr Lauren Walker	Olfactory bulb involvement in neurodegenerative diseases	2014
Professor Johannes Attems	Olfactory neurodegenerative pathology in neurodegenerative diseases	2014
Professor Johannes Attems	Primary age-related tauopathy (PART): a common pathology associated with human aging	2014
Professor Johannes Attems	Protease-resistant SOD1 aggregates in amyotrophic lateral sclerosis demonstrated by paraffin-embedded tissue (PET) blot	2014
Professor Johannes Attems Dr Lauren Walker Dr Sean Colloby Professor Alan Thomas	Pyroglutamylated Amyloid-beta correlates with Hyperphosphorylated Tau and Severity of Alzheimer's Disease	2014
Professor Johannes Attems Dr Sean Colloby	Pyroglutamylated amyloid-beta is associated with hyperphosphorylated tau in human post mortem brains	2014
Dr Lauren Walker Dr Peter Hanson Dr Sean Colloby Dr Christopher Morris Professor Alan Thomas et al.	Pyroglutamylated amyloid-β is associated with hyperphosphorylated tau and severity of Alzheimer’s disease	2014
Professor Johannes Attems	Quantitative neuropathological assessment to investigate cerebral multi-morbidity	2014
Professor Johannes Attems	Spreading of amyloid, tau, and microvascular pathology in alzheimer's disease: Findings from neuropathological and neuroimaging studies	2014
Professor Johannes Attems	The overlap between vascular disease and Alzheimer's disease - lessons from pathology	2014
Dr Francesco Vergani Professor Johannes Attems Dr Christopher Morris Patrick Mitchell	White matter connections of the supplementary motor area in humans	2014
Dr Kirsty McAleese Dr Michael Firbank Shane McParland Professor Johannes Attems	Axonal degeneration secondary to cortical neurodegeneration; a potential cause for white matter lesions?	2013
Yumi Yamamoto Dr Lucinda Craggs Professor Johannes Attems Arthur Oakley Professor Raj Kalaria et al.	Brain microvascular accumulation and distribution of GOM and the NOTCH3 ectodomain in CADASIL	2013
Yumi Yamamoto Dr Lucinda Craggs Dr Trevor Booth Professor Johannes Attems Arthur Oakley et al.	Brain Microvascular Accumulation and Distribution of the NOTCH3 Ectodomain and Granular Osmiophilic Material in CADASIL	2013
Dr Claire Troakes Professor Johannes Attems Annette King Professor Derek Mann	Diagnostic approach to Argyrophilic Grain Disease (AGD): an UK BDR trial	2013
Dr Kirsty McAleese Dr Michael Firbank Dr David Hunter Dr Li Sun Professor John O'Brien et al.	Magnetic resonance imaging of fixed post mortem brains reliably reflects subcortical vascular pathology of frontal, parietal and occipital white matter	2013
Professor Johannes Attems	Neurochemical mapping of the human hippocampus reveals perisynaptic matrix around functional synapses in Alzheimer's disease	2013
Professor Johannes Attems	Pathology of clinical and preclinical alzheimer's disease	2013
Lauren Walker Professor Alan Thomas Dr Christopher Morris Professor Johannes Attems	Quantification of pathology in mixed Alzheimer's disease and Lewy body dementia	2013
Shane McParland Dr Kirsty McAleese Dr Lauren Walker Mary Johnson Dr Ed Fielder et al.	Tissue microarray in the quantification of hyper-phosphorylated tau, amyloid-beta and alpha-synuclein	2013
Dr Rufus Akinyemi Dr Elizabeta Mukaetova-Ladinska Professor Johannes Attems Dr Masafumi Ihara Professor Raj Kalaria et al.	Vascular Risk Factors and Neurodegeneration in Ageing related Dementias: Alzheimer's Disease and Vascular Dementia	2013
Dr Lucinda Craggs Janet Slade Professor Johannes Attems Arthur Oakley Professor Raj Kalaria et al.	Cerebral Accumulation, Distribution and Clearance of GOM and NOTCH3 fragments in CADASIL	2012
Professor Johannes Attems	Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease	2012
Professor Johannes Attems Dr Laura Jardine Shane McParland	Clusters of secretagogin-expressing neurons in the aged human olfactory tract lack terminal differentiation	2012
Professor Johannes Attems	Comparative platelet proteome analysis reveals an increase of monoamine oxidase-B protein expression in Alzheimer's disease but not in non-demented Parkinson's disease patients	2012
Dr Kirsty McAleese Dr Michael Firbank Mary Johnson Dr Li Sun Roslyn Hall et al.	Magnetic resonance imaging detects subcortical vascular pathology in post mortem brains	2012
Dr Kirsty McAleese Dr Michael Firbank Dr David Hunter Dr Li Sun Roslyn Hall et al.	Magnetic resonance imaging detects subcortical vascular pathology in post mortem brains	2012
Emeritus Professor Elaine Perry Mary Johnson Emeritus Professor Robert Perry Dr Clive Ballard Professor Johannes Attems et al.	Neurogenic abnormalities in Alzheimer's disease differ between stages of neurogenesis and are partly related to cholinergic pathology	2012
Dr Sean Colloby Shane McParland Professor John O'Brien Professor Johannes Attems	Neuropathological correlates of dopaminergic imaging in Alzheimer's disease and Lewy body dementias	2012
Professor Johannes Attems	Neuropathology and general autopsy findings in nondemented aged subjects	2012
Professor Johannes Attems	The renaissance of Ca(2+)-binding proteins in the nervous system: secretagogin takes center stage	2012
Professor Johannes Attems	Age related changes in pancreatic beta cells: A putative extra-cerebral site of Alzheimer's pathology	2011
Professor Johannes Attems	Capillary CAA defines a subtype of Alzheimer's disease while pericapillary A beta is a type of early A beta deposition	2011
Professor Johannes Attems	Concordance between epidermal growth factor receptor status in primary non-small-cell lung cancer and metastases: still to be established [reply]	2011
Professor Johannes Attems	Concordance between epidermal growth factor receptor status in primary non-small-cell lung cancer and metastases: still to be established: Author Reply	2011
Professor Johannes Attems	In honor of the 80th birthday of Kurt Jellinger: a living legend in neuropathology	2011
Professor Johannes Attems	Prevalence and pathology of dementia with Lewy bodies in the oldest old: a comparison with other dementing disorders	2011
Professor Johannes Attems	Rapidly progressing diffuse Lewy body disease	2011
Professor Johannes Attems	Reduced secretagogin expression in the hippocampus of P301L tau transgenic mice	2011
Professor Johannes Attems	Sporadic cerebral amyloid angiopathy	2011
Professor Johannes Attems	Tangle dominant dementia - comparison with classical Alzheimer disease	2011
Professor Johannes Attems Dr Vincent Deramecourt Professor Raj Kalaria	The semi-quantitative assessment of subcortical small vessel disease pathology in elderly subjects: an initiative from the UK BD collaboration	2011
Professor Johannes Attems	Unclassifiable tauopathy associated with an A152T variation in MAPT exon 7	2011
Professor Johannes Attems	Capillary CAA and perivascular A beta-deposition: Two distinct features of Alzheimer's disease pathology	2010
Professor Johannes Attems	Capillary CAA and perivascular Abeta-deposition	2010
Professor Johannes Attems	Capillary cerebral amyloid angiopathy identifies a distinct APOE epsilon4-associated subtype of sporadic Alzheimer's disease	2010
Professor Johannes Attems	Concordance between epidermal growth factor receptor status in primary non-small-cell lung cancer and metastases: a post-mortem study	2010
Professor Johannes Attems	ErbB2/CEP17 and total ErbB2 copy number as independent forecast factor for time to First Metastasis (TTM) and with a trastuzumab-based therapy in HER2 testing metasase breast cancer [abstract]	2010
Professor Johannes Attems	Expression of TAU in insulin-secreting cells and its interaction with the calcium-binding protein secretagogin	2010
Professor Johannes Attems	Is there pure vascular dementia in old age?	2010
Professor Johannes Attems	Is there pure vascular dementia in old age?	2010
Professor Johannes Attems	Prevalence and pathology of vascular dementia in the oldest old	2010
Professor Johannes Attems	Prevalence of dementia disorders in the oldest-old: an autopsy study	2010
Professor Johannes Attems	[abstract] A 18-year-old Girl with Fever, Cough, and cystic Lesions in the Lungs	2009
Professor Johannes Attems	[abstract] EGFR status of primary NSCLC remains unchanged in lymph node and organ metastases: An autopsy study	2009
Professor Johannes Attems	[abstract] The abscess formation by Cryptococcus neoformans with underlying Sarcoide and distinct immunodeficiency	2009
Professor Johannes Attems	Amyloid PET and MRI in Alzheimer's disease and mild cognitive impairment	2009
Professor Johannes Attems	Different Neprilysin expression in vessels of occipital and frontal lobes	2009
Professor Johannes Attems	Neuropathology of age-associated neurodegenerative diseases	2009
Professor Johannes Attems	Neuropathology of Parkinson's disease dementia and dementia with Lewy bodies	2009
Professor Johannes Attems	Sporadic cerebral amyloid angiopathy-No frequent cause of spontaneous brain hemorrhage in the aged	2009
Professor Johannes Attems	Biomarkers for early diagnosis of Alzheimer disease: 'ALZheimer ASsociated gene'-a new blood biomarker?	2008
Professor Johannes Attems	Calcium binding protein secretagogin and neuroprotection in Alzheimer's disease	2008
Professor Johannes Attems	Calcium-binding protein secretagogin-expressing neurones in the human hippocampus are largely resistant to neurodegeneration in Alzheimer's disease	2008
Professor Johannes Attems	Cerebral amyloid angiopathy in Lewy body disease	2008
Professor Johannes Attems	Cerebral amyloid angiopathy in Lewy body disease	2008
Professor Johannes Attems	Ewing's sarcoma and peripheral primitive neuroectodermal tumor in adults: different features of a rare neoplasm	2008
Professor Johannes Attems	Neuropathology of Parkinson's disease Dementia (PDD) and Dementia with Lewy bodies (DLB)	2008
Professor Johannes Attems	Prevalence and impact of vascular and Alzheimer pathologies in Lewy body disease	2008
Professor Johannes Attems	Secretagogin is expressed in hippocampal neurones of wild type but not of tau-homocygote (P301L) mice	2008
Professor Johannes Attems	The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease	2008
Professor Johannes Attems	Unexpectedly low prevalence of intracerebral hemorrhages in sporadic cerebral amyloid angiopathy: an autopsy study	2008
Professor Johannes Attems	Catheter-related Leuconostoc bacteremia secondary to pulmonary Mycobacterium xenopi infection	2007
Professor Johannes Attems	Down-regulation of Sprouty2 in non-small cell lung cancer contributes to tumor malignancy via extracellular signal-regulated kinase pathway-dependent and -independent mechanisms	2007
Professor Johannes Attems	Immunoreactivity of calcium binding protein secretagogin in the human hippocampus is restricted to pyramidal neurons	2007
Professor Johannes Attems	Intratumoral IGF-I protein expression is selectively upregulated in breast cancer patients with BRCA1/2 mutations	2007
Professor Johannes Attems	Mechanisms involved in the regulation of Sprouty4 expression	2007
Professor Johannes Attems	Neurofibrillary tangle-predominant dementia: comparison with classical Alzheimer disease	2007
Professor Johannes Attems	Neuropathological evaluation of mixed dementia	2007
Professor Johannes Attems	Secretagogin expressing neurons in the human hippocampus are resistant to neurodegeneration in Alzheimer's disease	2007
Professor Johannes Attems	Sporadic cerebral amyloid angiopathy is not a frequent cause of spontaneous brain hemorrhage	2007
Professor Johannes Attems	Tau and alpha-synuclein brainstem pathology in Alzheimer disease: relation with extrapyramidal signs	2007
Professor Johannes Attems	Topographical distribution of cerebral amyloid angiopathy and its effect on cognitive decline are influenced by Alzheimer disease pathology	2007
Professor Johannes Attems	[abstract] Tau and alpha-syunclein brainstem lesions in Alzheimer disease	2006
Professor Johannes Attems	Does striatal pathology distinguish Parkinson disease with dementia and dementia with Lewy bodies?	2006
Professor Johannes Attems	Her-2/neu and EGFR tyrosine kinase activation predict the efficacy of trastuzumab-based therapy in patients with metastatic breast cancer	2006
Professor Johannes Attems	Hippocampal sclerosis in Alzheimer disease and other dementias	2006
Professor Johannes Attems	Intratumoral IGF-1 protein expression is selectively up-regulated in breast cancer patients with BRCA1/2 mutations	2006
Professor Johannes Attems	Lung disease 35 years after aspiration of activated charcoal in combination with pulmonary lymphangioleiomyomatosis. A histological and clinicopathological study with scanning electron microscopic evaluation and element analysis	2006
Professor Johannes Attems	Olfactory tau pathology in Alzheimer disease and mild cognitive impairment	2006
Professor Johannes Attems	Prevalence and impact of cerebrovascular pathology in Alzheimer's disease and parkinsonism	2006
Professor Johannes Attems	Tau and alpha-synuclein brainstem pathology in Alzheimer disease	2006
Professor Johannes Attems	Alzheimer pathology in the olfactory bulb	2005
Professor Johannes Attems	Alzheimer's disease pathology influences severity and topographical distribution of cerebral amyloid angiopathy	2005
Professor Johannes Attems	Cause of death in demented and non-demented elderly inpatients; an autopsy study of 308 cases	2005
Professor Johannes Attems	Expression of a piggy-back-gene determines Alzheimer disease pathology?	2005
Professor Johannes Attems	Multidrug resistance markers P-glycoprotein, multidrug resistance protein 1, and lung resistance protein in non-small cell lung cancer: prognostic implications	2005
Professor Johannes Attems	Olfactory involvement in ageing and Alzheimer disease	2005
Professor Johannes Attems	Olfactory involvement in aging and Alzheimer's disease: an autopsy study	2005
Professor Johannes Attems	Olfactory pathology in aging and Alzheimer disease	2005
Professor Johannes Attems	Prevalence and pathogenic role of cerebrovascular lesions in Alzheimer disease	2005
Professor Johannes Attems	Sporadic cerebral amyloid angiopathy: pathology, clinical implications, and possible pathomechanisms	2005
Professor Johannes Attems	Tau and alpha-synuclein brainstem pathology in Alzheimer disease	2005
Professor Johannes Attems	The efficacy of trastuzumab in Her-2/neu-overexpressing metastatic breast cancer is independent of p53 status	2005
Professor Johannes Attems	[correction] Amyloid beta peptide 1-42 highly correlates with capillary cerebral amyloid angiopathy and Alzheimer disease pathology (vol 107, pg 283, 2004)	2004
Professor Johannes Attems	A proteomic and immunhistochemical approach to the study of Alzheimer disease	2004
Professor Johannes Attems	Active Her-2/neu signal transduction in breast cancer - relevance of a ligand-independent activation mechanism and impact an the efficacy of trastuzumab-based treatment	2004
Professor Johannes Attems	Amyloid beta peptide 1-42 highly correlates with capillary cerebral amyloid angiopathy and Alzheimer disease pathology	2004
Professor Johannes Attems	Only cerebral capillary amyloid angiopathy correlates with Alzheimer pathology-a pilot study	2004
Professor Johannes Attems	Relations between cerebral amyloid angiopathy and Alzheimer's disease pathology	2004
Professor Johannes Attems	The clinical diagnostic accuracy rate regarding the immediate cause of death in a hospitalized geriatric population; an autopsy study of 1594 patients	2004
Professor Johannes Attems	Her-2/neu-triggered intracellular tyrosine kinase activation: in vivo relevance of ligand-independent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment	2003
Professor Johannes Attems	Incidence of cerebrovascular lesions in Alzheimer's disease: a postmortem study	2003
Professor Johannes Attems	Pseudomesotheliomatous adenocarcinoma of the lung with rhabdoid features	2001