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Browsing publications by Professor Johannes Attems.

Newcastle AuthorsTitleYearFull text
Dr Calum Hamilton
Professor Fiona Matthews
Professor Johannes Attems
Dr Paul Donaghy
Dr Daniel Erskine
et al.
Associations between multimorbidity and neuropathology in dementia: Consideration of functional cognitive disorders, psychiatric illness and dementia mimics2024
Professor Johannes Attems
Biomarker-Based Approach to α-Synucleinopathies: Lessons from Neuropathology2024
Professor Johannes Attems
Professor Ian McKeith
Dr Christopher Morris
Investigation of the genetic aetiology of Lewy body diseases with and without dementia2024
Dr Lauren Walker
Professor Johannes Attems
Prevalence of Concomitant Pathologies in Parkinson's Disease: Implications for Prognosis, Diagnosis, and Insights into Common Pathogenic Mechanisms2024
Dr Lauren Walker
Professor Alan Thomas
Professor Johannes Attems
Prevalence, distribution, and severity of cerebral amyloid angiopathy differ between Lewy body diseases and Alzheimer’s disease2024
Jessica Katanga
Dr Calum Hamilton
Dr Lauren Walker
Professor Johannes Attems
Professor Alan Thomas
et al.
Age-related hearing loss and dementia-related neuropathology: An analysis of the United Kingdom brains for dementia research cohort2023
Professor Tiago Outeiro
Professor Johannes Attems
Professor Ian McKeith
Defining the Riddle in Order to Solve It: There Is More Than One "Parkinson's Disease"2023
Professor Johannes Attems
Dopamine and vesicular monoamine transport loss supports incidental Lewy body disease as preclinical idiopathic Parkinson2023
Professor Johannes Attems
Kirsty McAleese
LATE-NC staging in routine neuropathologic diagnosis: an update2023
Professor Carol Brayne
Professor Johannes Attems
Professor Fiona Matthews
Dr Tuomo Polvikoski
Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts2022
Professor Johannes Attems
Genome-wide association study and functional validation implicates JADE1 in tauopathy2022
Professor Johannes Attems
Interpretable deep learning of myelin histopathology in age-related cognitive impairment2022
Professor Johannes Attems
Mitochondrial dysfunction is a key pathological driver of early stage Parkinson's2022
Dr David Koss
Dr Daniel Erskine
Dr Andrew Porter
Dr Pawel Palmowski
Professor Johannes Attems
et al.
Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies.2022
Chris Hatton
Dr David Koss
Dr Lauren Walker
Professor Tiago Outeiro
Professor Johannes Attems
et al.
Prion-like α-synuclein pathology in the brain of infants with Krabbe disease2022
Dr Daniel Erskine
Professor Johannes Attems
Professor Ian McKeith
Professor Tiago Outeiro
α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity2022
Professor Johannes Attems
123I FP-CIT SPECT in dementia with Lewy bodies, Parkinson's disease and Alzheimer's disease: a new quantitative analysis of autopsy confirmed cases2021
Professor Johannes Attems
Discovery of autism/intellectual disability somatic mutations in Alzheimer's brains: mutated ADNP cytoskeletal impairments and repair as a case study2021
Professor Johannes Attems
Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy2021
Dr Kirsty McAleese
Mohi Miah
Dr Lauren Walker
Mary Johnson
Dr Sean Colloby
et al.
Frontal white matter lesions in Alzheimer’s disease are associated with both small vessel disease and AD-associated cortical pathology2021
Professor Johannes Attems
Professor Alan Thomas
Genetic risk for Alzheimer's disease influences neuropathology via multiple biological pathways2021
Dr Daniel Erskine
Professor Johannes Attems
Insights into Lewy body disease from rare neurometabolic disorders2021
Dr Daniel Erskine
Dr David Koss
Professor Viktor Korolchuk
Professor Tiago Outeiro
Professor Johannes Attems
et al.
Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders2021
Dr Calum Hamilton
Professor Fiona Matthews
Dr Daniel Erskine
Professor Johannes Attems
Professor Alan Thomas
et al.
Neurodegenerative brain changes are associated with area deprivation in the United Kingdom: findings from the Brains for Dementia Research study2021
Dr Marzena Kurzawa-Akanbi
Dr Michael Keogh
Eliona Tsefou
Lynne Ramsay
Mary Johnson
et al.
Neuropathological and Biochemical Investigation of Hereditary Ferritinopathycases with Ferritin Light Chain Mutation: Prominent Protein Aggregation in the Absence of Major Mitochondrial or Oxidative Stress2021
Professor Johannes Attems
Dr Lauren Walker
Dr Kirsty McAleese
Dr Tuomo Polvikoski
Professor Ian McKeith
et al.
Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study2021
Dr David Koss
Odeta Bondarevaite
Professor Johannes Attems
Professor Tiago Outeiro
RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies2021
Chris Hatton
Dr Amy Reeve
Dr Nichola Lax
Dr Alasdair Blain
Dr Yi Ng
et al.
Complex I reductions in the nucleus basalis of Meynert in Lewy body dementia: the role of Lewy bodies2020
Dr Kirsty McAleese
Dr Lauren Walker
Dr Daniel Erskine
Mary Johnson
Dr David Koss
et al.
Concomitant LATE-NC in Alzheimer's disease is not associated with increased tau or amyloid-β pathological burden2020
Professor Johannes Attems
Fulminant corticobasal degeneration: a distinct variant with predominant neuronal tau aggregates2020
Dr Daniel Erskine
Dr Christopher Morris
Professor Johannes Attems
Investigating the Presence of Doubly‐phosphorylated α‐Synuclein at Tyrosine 125 and Serine 129 In Idiopathic Lewy Body Diseases2020
Dr Daniel Erskine
Dr Amy Reeve
Dr Tuomo Polvikoski
Dr Andrew Schaefer
Professor Robert Taylor
et al.
Lewy body pathology is more prevalent in older individuals with mitochondrial disease than controls2020
Dr Kirsty McAleese
Professor Johannes Attems
Professor Alan Thomas
Neuropsychiatric symptoms in limbic-predominant age-related TDP-43 encephalopathy and Alzheimer's disease2020
Mary Johnson
Professor Johannes Attems
The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies2020
Professor Johannes Attems
The Pattern of AQP4 Expression in the Ageing Human Brain and in Cerebral Amyloid Angiopathy2020
Professor Johannes Attems
Vascular α1a adrenergic receptors as a potential therapeutic target for ipad in alzheimer’s disease2020
Dr Lauren Walker
Professor Johannes Attems
Clinical and neuropathological differences between Parkinson's disease, Parkinson's disease dementia and dementia with Lewy bodies – current issues and future directions2019
Dr David Koss
Mary Johnson
Professor Johannes Attems
Professor Tiago Outeiro
Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies2019
Lina Patterson
Professor Stephen Rushton
Professor Johannes Attems
Professor Alan Thomas
Dr Christopher Morris
et al.
Degeneration of dopaminergic circuitry influences depressive symptoms in Lewy body disorders2019
Professor Tiago Outeiro
Dr David Koss
Dr Daniel Erskine
Dr Lauren Walker
Abishek Umashankar
et al.
Dementia with Lewy bodies: an update and outlook2019
Dr Kirsty McAleese
Madhurima Dey
Dr Lauren Walker
Dr Daniel Erskine
Mary Johnson
et al.
Extravascular fibrinogen in the white matter of Alzheimer’s disease and normal aged brains: implications for fibrinogen as a biomarker for Alzheimer’s disease2019
Dr Peter Kullar
Dr Ian Wilson
Professor Johannes Attems
Dr Christopher Morris
Frequency and signature of somatic variants in 1461 human brain exomes2019
Dr Christopher Morris
Professor Johannes Attems
Professor Tim Griffiths
Professor Ian McKeith
Professor Alan Thomas
et al.
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia2019
Dr Christopher Morris
Professor Johannes Attems
Professor Tim Griffiths
Professor Ian McKeith
Professor Alan Thomas
et al.
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia2019
Professor Johannes Attems
Professor Carol Brayne
Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report2019
Professor Johannes Attems
Dr Dag Aarsland
Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration2019
Dr Lauren Walker
Dr Kirsty McAleese
Dr Daniel Erskine
Professor Johannes Attems
Neurodegenerative Diseases and Ageing2019
Lina Patterson
Dr Michael Firbank
Dr Sean Colloby
Professor Johannes Attems
Professor Alan Thomas
et al.
Neuropathological Changes in Dementia With Lewy Bodies and the Cingulate Island Sign2019
Dr Thomas Meyer
Professor Johannes Attems
Professor Tiago Outeiro
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein2019
Dr Daniel Erskine
Professor John-Paul Taylor
Professor Alan Thomas
Daniel Collerton
Professor Ian McKeith
et al.
Pathological Changes to the Subcortical Visual System and its Relationship to Visual Hallucinations in Dementia with Lewy Bodies2019
Professor Nicola Pavese
Professor Johannes Attems
Rare histotype of sporadic Creutzfeldt-Jakob disease, clinically suspected as corticobasal degeneration2019
Professor Johannes Attems
Professor Carol Brayne
Reply: LATE to the PART-y2019
Professor Johannes Attems
The first year2019
Dr James Lloyd
Dr George Petrides
Dr Paul Donaghy
Dr Sean Colloby
Professor Johannes Attems
et al.
A new visual rating scale for Ioflupane imaging in Lewy body disease2018
Dr Kirsty McAleese
Dr Lauren Walker
Dr Sean Colloby
Professor John-Paul Taylor
Professor Alan Thomas
et al.
Cortical tau pathology: A major player in fibre-specific white matter reductions in Alzheimer's disease?2018
Mary Johnson
Dr Ahmad Khundakar
Professor Johannes Attems
Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-β plaques: A potential role in shaping plaque pathology?2018
Dr Lauren Walker
Dr Jonathan Coxhead
Dr Ian Wilson
Dr Matthew Bashton
Dr Christopher Morris
et al.
High prevalence of focal and multi-focal somatic genetic variants in the human brain2018
Professor Alan Thomas
Dr Fariba Mahin-Babaei
Dr Mohammad Saidi
Debbie Lett
Professor John-Paul Taylor
et al.
Improving the identification of dementia with Lewy bodies in the context of an Alzheimer’s-type dementia2018
Professor Johannes Attems
Dr Kirsty McAleese
Dr Lauren Walker
Methods for pathological classification of Alzheimer's disease2018
Dr Daniel Erskine
Professor Alan Thomas
Dr Ahmad Khundakar
Dr Peter Hanson
Professor John-Paul Taylor
et al.
Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies2018
Professor Johannes Attems
Neuropathology and biochemistry of early onset familial Alzheimer’s disease caused by presenilin-1 missense mutation Thr116Asn2018
Dr Michael Keogh
Dr Wei Wei
Dr Ian Wilson
Professor Johannes Attems
Dr Christopher Morris
et al.
Oligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains2018
Dr Bernadette Carroll
Diego Manni
Dr Rhoda Stefanatos
Fiona Menzies
Dr Graham Smith
et al.
Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis2018
Professor Johannes Attems
Phosphorylation of different tau sites during progression of Alzheimer's disease2018
Professor Johannes Attems
Proteomics for synaptic markers of cognitive decline in neurodegenerative diseases2018
Dr Daniel Erskine
Lina Patterson
Dr Athanasios Alexandris
Dr Peter Hanson
Professor Ian McKeith
et al.
Regional levels of physiological α-synuclein are directly associated with Lewy body pathology2018
Professor Johannes Attems
SIRT1, miR-132 and miR-212 link human longevity to Alzheimer's Disease2018
Dr Christopher Morris
Professor Johannes Attems
Somatic variants in autosomal dominant genes are a rare cause of sporadic Alzheimer's disease2018
Professor Johannes Attems
Alzheimer's disease pathology in synucleinopathies2017
Professor Alan Thomas
Professor Johannes Attems
Dr Sean Colloby
Professor John O'Brien
Professor Ian McKeith
et al.
Author response: Autopsy validation of 123 I-FP-CIT dopaminergic neuroimaging for the diagnosis of DLB2017
Professor Alan Thomas
Professor Johannes Attems
Dr Sean Colloby
Professor John O'Brien
Professor Ian McKeith
et al.
Autopsy validation of 123 I-FP-CIT dopaminergic neuroimaging for the diagnosis of DLB2017
Professor Johannes Attems
Common Impact of Chronic Kidney Disease and Brain Microhemorrhages on Cerebral Aβ Pathology in SHRSP2017
Professor Ian McKeith
Professor John-Paul Taylor
Dr Dag Aarsland
Professor Johannes Attems
Dr Clive Ballard
et al.
Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium2017
Dr Michael Keogh
Dr Wei Wei
Dr Ian Wilson
Dr Jonathan Coxhead
Dr Helen Griffin
et al.
Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource2017
Professor Johannes Attems
Interactions of pathological proteins in neurodegenerative diseases2017
Dr Michael Keogh
Dr Ian Wilson
Dr Jonathan Coxhead
Dr Helen Griffin
Dr Marzena Kurzawa-Akanbi
et al.
Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains2017
Dr Daniel Erskine
Professor Alan Thomas
Professor John-Paul Taylor
Michael Savage
Professor Johannes Attems
et al.
Neuronal Loss and Α-Synuclein Pathology in the Superior Colliculus and Its Relationship to Visual Hallucinations in Dementia with Lewy Bodies2017
Dr Kirsty McAleese
Dr Lauren Walker
Mary Johnson
Dr Daniel Erskine
Dr Sean Colloby
et al.
Parietal white matter lesions in Alzheimer's disease are associated with cortical neurodegenerative pathology, but not with small vessel disease2017
Dr Lauren Walker
Dr Kirsty McAleese
Mary Johnson
Dr Ahmad Khundakar
Dr Daniel Erskine
et al.
Quantitative neuropathology: an update on automated methodologies and implicationsfor large scale cohorts2017
Olivia Skrobot
Professor Johannes Attems
Professor Raj Kalaria
Reply: Atherosclerosis and vascular cognitive impairment neuropathological guideline2017
Dr Daniel Erskine
Professor Alan Thomas
Professor Johannes Attems
Professor John-Paul Taylor
Professor Ian McKeith
et al.
Specific patterns of neuronal loss in the pulvinar nucleus in dementia with Lewy bodies2017
Mary Johnson
Professor Raj Kalaria
Professor Johannes Attems
Systems proteomic analysis reveals that clusterin and tissue inhibitor of metalloproteinases 3 increase in leptomeningeal arteries affected by cerebral amyloid angiopathy2017
Dr Kirsty McAleese
Dr Lauren Walker
Dr Daniel Erskine
Professor Alan Thomas
Professor Ian McKeith
et al.
TDP-43 pathology in Alzheimer's disease, dementia with Lewy bodies and ageing2017
Professor Johannes Attems
The multi-morbid old brain2017
Professor Johannes Attems
Richard Heale
Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy2016
Professor Johannes Attems
An isoform-specific role of FynT tyrosine kinase in Alzheimer's disease2016
Dr Ahmad Khundakar
Dr Peter Hanson
Dr Daniel Erskine
Dr Nichola Lax
Evangelia Karyka
et al.
Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations2016
Dr Francesco Vergani
Dr Christopher Morris
Professor Johannes Attems
Anatomic Connections of the Subgenual Cingulate Region2016
Professor Johannes Attems
Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord2016
Mary Johnson
Professor Johannes Attems
Professor John O'Brien
Professor Alan Thomas
Decreased Levels of VAMP2 and Monomeric Alpha-Synuclein Correlate with Duration of Dementia2016
Professor Johannes Attems
Dementia in Parkinson's disease is associated with enhanced mitochondrial complex I deficiency2016
Professor Johannes Attems
Professor Raj Kalaria
Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy2016
Professor Johannes Attems
Erratum to: Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord (Brain Struct Funct, 10.1007/s00429-016-1191-3)2016
Dr Michael Keogh
Dr Marzena Kurzawa-Akanbi
Dr Helen Griffin
Dr Konstantinos Douroudis
Dr Kristin Ayers
et al.
Exome sequencing in dementia with Lewy bodies2016
Debbie Lett
Professor Johannes Attems
Dr Christopher Morris
Extended post-mortem delay times should not be viewed as a deterrent to the scientific investigation of human brain tissue: a study from the Brains for Dementia Research Network Neuropathology Study Group, UK2016
Dr Lauren Walker
Professor Alan Thomas
Debbie Lett
Dr Kirsty McAleese
Mary Johnson
et al.
Investigating the pathological correlate of motor dysfunction in DLB and PDD2016
Professor Johannes Attems
Is the time ripe for new diagnostic criteria of cognitive impairment due to cerebrovascular disease? Consensus report of the International Congress on Vascular Dementia working group2016
Dr Kirsty McAleese
Professor Raj Kalaria
Professor Johannes Attems
Post-mortem assessment in vascular dementia: advances and aspirations2016
Professor Johannes Attems
Proteomic characterization of neuromelanin granules isolated from human substantia nigra by laser-microdissection2016
Professor Johannes Attems
Dr Clive Ballard
Dr Dag Aarsland
Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia2016
Professor Johannes Attems
The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells2016
Dr Kirsty McAleese
Dr Lauren Walker
Dr Daniel Erskine
Professor Johannes Attems
The prevalence of TDP-43 pathology in Alzheimer's disease, Lewy body dementia and mixed Alzheimer's disease and Lewy body disease2016
Professor Johannes Attems
Unfolded protein response is activated in Lewy body dementias2016
Olivia Skrobot
Professor Johannes Attems
Professor Raj Kalaria
Vascular Cognitive Impairment Neuropathology Guidelines (VCING) - a UK multi-centre consensus study2016
Olivia Skrobot
Professor Johannes Attems
Professor Raj Kalaria
Vascular cognitive impairment neuropathology guidelines (VCING): the contribution of cerebrovascular pathology to cognitive impairment2016
Dr Stephen Jaiser
Professor Johannes Attems
Dr Timothy Williams
A case of facial onset sensory and motor neuronopathy (FOSMN) associated with TDP-43 proteinopathy2015
Professor Johannes Attems
Challenges of multimorbidity of the aging brain: a critical update2015
Dr Daniel Erskine
Professor John-Paul Taylor
Dr Michael Firbank
Professor John O'Brien
Professor Ian McKeith
et al.
Changes to the lateral geniculate nucleus in Alzheimer's disease but not dementia with Lewy bodies2015
Dr Pietro Tiraboschi
Professor Johannes Attems
Professor Alan Thomas
Dr Evelyn Jaros
Debbie Lett
et al.
Clinicians' ability to diagnose dementia with Lewy bodies is not affected by β Normal 0 false false false EN-GB X-NONE X-NONE -amyloid load2015
Dr Kirsty McAleese
Dr Michael Firbank
Madhurima Dey
Dr Sean Colloby
Dr Lauren Walker
et al.
Cortical tau load is associated with white matter hyperintensities2015
Dr Timothy Williams
Dr Stephan Jaiser
Professor Johannes Attems
Facial Onset Sensory and Motor Neuronopathy: Further Evidence for a TDP-43 Proteinopathy2015
Dr Lauren Walker
Professor Johannes Attems
Frontotemporal lobar degeneration FTLD-tau: preclinical lesions, vascular, and Alzheimer-related co-pathologies2015
Professor Johannes Attems
Professor Raj Kalaria
Global proteomic profiling of brain leptomeningeal arteries from patients with cerebral amyloid angiopathy reveals novel therapeutic targets2015
Dr Lauren Walker
Dr Kirsty McAleese
Professor Alan Thomas
Mary Johnson
Dr Carmen Martin-Ruiz
et al.
Neuropathologically mixed Alzheimer's and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes2015
Professor Johannes Attems
Dr Lauren Walker
Olfaction and Aging: A Mini-Review2015
Professor Johannes Attems
PART, a distinct tauopathy, different from classical sporadic Alzheimer disease2015
Professor Johannes Attems
Professor John O'Brien
Dr Dag Aarsland
Dr Clive Ballard
Regional Multiple Pathology Scores Are Associated with Cognitive Decline in Lewy Body Dementias2015
Professor Johannes Attems
Spreading pathologies precede cognitive decline in Alzheimer's disease2015
Professor Carol Brayne
Mary Johnson
Emeritus Professor Elaine Perry
Professor Johannes Attems
Dr Clive Ballard
et al.
Stage-Specific Changes in Neurogenic and Glial Markers in Alzheimer's Disease2015
Dr Alison Spilsbury
Dr Satomi Miwa
Professor Johannes Attems
Dr Gabriele Saretzki
The Role of Telomerase Protein TERT in Alzheimer's Disease and in Tau-Related Pathology In Vitro2015
Professor Johannes Attems
A platelet protein biochip rapidly detects an Alzheimer’s disease-specific phenotype2014
Professor Johannes Attems
Amyloidosis2014
Mary Johnson
Professor Johannes Attems
Dr Clive Ballard
Professor Alan Thomas
Professor John O'Brien
et al.
Assessment of ZnT3 and PSD95 protein levels in Lewy body dementias and Alzheimer's disease: association with cognitive impairment2014
Dr Kirsty McAleese
Madhurima Dey
Dr Michael Firbank
Shane McParland
Professor John O'Brien
et al.
Cortical neurodegenerative pathology has an influence on white matter integrity2014
Professor Johannes Attems
Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue2014
Mary Johnson
Professor Johannes Attems
Dr Clive Ballard
Professor Alan Thomas
Professor John O'Brien
et al.
Dynamin1 concentration in the prefrontal cortex is associated with cognitive impairment in Lewy body dementia2014
Dr Christopher Morris
Professor Johannes Attems
Professor Tim Griffiths
Professor Ian McKeith
Professor Alan Thomas
et al.
Frontotemporal dementia and its subtypes: a genome-wide association study2014
Professor Johannes Attems
High-level ERBB2 gene amplification is associated with a particularly short time-to-metastasis, but results in a high rate of complete response once trastuzumab-based therapy is offered in the metastatic setting2014
Professor Johannes Attems
Interplay between age, cerebral small vessel disease, parenchymal amyloid-β, and tau pathology: Longitudinal studies in hypertensive stroke-prone rats2014
Professor Raj Kalaria
Professor Johannes Attems
Microvascular Pathology2014
Mary Johnson
Emeritus Professor Elaine Perry
Professor Johannes Attems
Neurogenic marker alterations in the hippocampus in relation to cholinergic therapy in Lewy Body dementia2014
Professor Johannes Attems
Dr Lauren Walker
Olfactory bulb involvement in neurodegenerative diseases2014
Professor Johannes Attems
Olfactory neurodegenerative pathology in neurodegenerative diseases2014
Professor Johannes Attems
Primary age-related tauopathy (PART): a common pathology associated with human aging2014
Professor Johannes Attems
Protease-resistant SOD1 aggregates in amyotrophic lateral sclerosis demonstrated by paraffin-embedded tissue (PET) blot2014
Professor Johannes Attems
Dr Lauren Walker
Dr Sean Colloby
Professor Alan Thomas
Pyroglutamylated Amyloid-beta correlates with Hyperphosphorylated Tau and Severity of Alzheimer's Disease2014
Professor Johannes Attems
Dr Sean Colloby
Pyroglutamylated amyloid-beta is associated with hyperphosphorylated tau in human post mortem brains2014
Dr Lauren Walker
Dr Peter Hanson
Dr Sean Colloby
Dr Christopher Morris
Professor Alan Thomas
et al.
Pyroglutamylated amyloid-β is associated with hyperphosphorylated tau and severity of Alzheimer’s disease2014
Professor Johannes Attems
Quantitative neuropathological assessment to investigate cerebral multi-morbidity2014
Professor Johannes Attems
Spreading of amyloid, tau, and microvascular pathology in alzheimer's disease: Findings from neuropathological and neuroimaging studies2014
Professor Johannes Attems
The overlap between vascular disease and Alzheimer's disease - lessons from pathology2014
Dr Francesco Vergani
Professor Johannes Attems
Dr Christopher Morris
Patrick Mitchell
White matter connections of the supplementary motor area in humans2014
Dr Kirsty McAleese
Dr Michael Firbank
Shane McParland
Professor Johannes Attems
Axonal degeneration secondary to cortical neurodegeneration; a potential cause for white matter lesions?2013
Yumi Yamamoto
Dr Lucinda Craggs
Professor Johannes Attems
Arthur Oakley
Professor Raj Kalaria
et al.
Brain microvascular accumulation and distribution of GOM and the NOTCH3 ectodomain in CADASIL2013
Yumi Yamamoto
Dr Lucinda Craggs
Dr Trevor Booth
Professor Johannes Attems
Arthur Oakley
et al.
Brain Microvascular Accumulation and Distribution of the NOTCH3 Ectodomain and Granular Osmiophilic Material in CADASIL2013
Dr Claire Troakes
Professor Johannes Attems
Annette King
Professor Derek Mann
Diagnostic approach to Argyrophilic Grain Disease (AGD): an UK BDR trial2013
Dr Kirsty McAleese
Dr Michael Firbank
Dr David Hunter
Dr Li Sun
Professor John O'Brien
et al.
Magnetic resonance imaging of fixed post mortem brains reliably reflects subcortical vascular pathology of frontal, parietal and occipital white matter2013
Professor Johannes Attems
Neurochemical mapping of the human hippocampus reveals perisynaptic matrix around functional synapses in Alzheimer's disease2013
Professor Johannes Attems
Pathology of clinical and preclinical alzheimer's disease2013
Lauren Walker
Professor Alan Thomas
Dr Christopher Morris
Professor Johannes Attems
Quantification of pathology in mixed Alzheimer's disease and Lewy body dementia2013
Shane McParland
Dr Kirsty McAleese
Dr Lauren Walker
Mary Johnson
Dr Edward Fielder
et al.
Tissue microarray in the quantification of hyper-phosphorylated tau, amyloid-beta and alpha-synuclein2013
Dr Rufus Akinyemi
Dr Elizabeta Mukaetova-Ladinska
Professor Johannes Attems
Dr Masafumi Ihara
Professor Raj Kalaria
et al.
Vascular Risk Factors and Neurodegeneration in Ageing related Dementias: Alzheimer's Disease and Vascular Dementia2013
Dr Lucinda Craggs
Janet Slade
Professor Johannes Attems
Arthur Oakley
Professor Raj Kalaria
et al.
Cerebral Accumulation, Distribution and Clearance of GOM and NOTCH3 fragments in CADASIL2012
Professor Johannes Attems
Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease2012
Professor Johannes Attems
Dr Laura Jardine
Shane McParland
Clusters of secretagogin-expressing neurons in the aged human olfactory tract lack terminal differentiation2012
Professor Johannes Attems
Comparative platelet proteome analysis reveals an increase of monoamine oxidase-B protein expression in Alzheimer's disease but not in non-demented Parkinson's disease patients2012
Dr Kirsty McAleese
Dr Michael Firbank
Mary Johnson
Dr Li Sun
Roslyn Hall
et al.
Magnetic resonance imaging detects subcortical vascular pathology in post mortem brains2012
Dr Kirsty McAleese
Dr Michael Firbank
Dr David Hunter
Dr Li Sun
Roslyn Hall
et al.
Magnetic resonance imaging detects subcortical vascular pathology in post mortem brains2012
Emeritus Professor Elaine Perry
Mary Johnson
Emeritus Professor Robert Perry
Dr Clive Ballard
Professor Johannes Attems
et al.
Neurogenic abnormalities in Alzheimer's disease differ between stages of neurogenesis and are partly related to cholinergic pathology2012
Dr Sean Colloby
Shane McParland
Professor John O'Brien
Professor Johannes Attems
Neuropathological correlates of dopaminergic imaging in Alzheimer's disease and Lewy body dementias2012
Professor Johannes Attems
Neuropathology and general autopsy findings in nondemented aged subjects2012
Professor Johannes Attems
The renaissance of Ca(2+)-binding proteins in the nervous system: secretagogin takes center stage2012
Professor Johannes Attems
Age related changes in pancreatic beta cells: A putative extra-cerebral site of Alzheimer's pathology2011
Professor Johannes Attems
Capillary CAA defines a subtype of Alzheimer's disease while pericapillary A beta is a type of early A beta deposition2011
Professor Johannes Attems
Concordance between epidermal growth factor receptor status in primary non-small-cell lung cancer and metastases: still to be established [reply]2011
Professor Johannes Attems
Concordance between epidermal growth factor receptor status in primary non-small-cell lung cancer and metastases: still to be established: Author Reply2011
Professor Johannes Attems
In honor of the 80th birthday of Kurt Jellinger: a living legend in neuropathology2011
Professor Johannes Attems
Prevalence and pathology of dementia with Lewy bodies in the oldest old: a comparison with other dementing disorders2011
Professor Johannes Attems
Rapidly progressing diffuse Lewy body disease2011
Professor Johannes Attems
Reduced secretagogin expression in the hippocampus of P301L tau transgenic mice2011
Professor Johannes Attems
Sporadic cerebral amyloid angiopathy2011
Professor Johannes Attems
Tangle dominant dementia - comparison with classical Alzheimer disease2011
Professor Johannes Attems
Dr Vincent Deramecourt
Professor Raj Kalaria
The semi-quantitative assessment of subcortical small vessel disease pathology in elderly subjects: an initiative from the UK BD collaboration2011
Professor Johannes Attems
Unclassifiable tauopathy associated with an A152T variation in MAPT exon 72011
Professor Johannes Attems
Capillary CAA and perivascular A beta-deposition: Two distinct features of Alzheimer's disease pathology2010
Professor Johannes Attems
Capillary CAA and perivascular Abeta-deposition2010
Professor Johannes Attems
Capillary cerebral amyloid angiopathy identifies a distinct APOE epsilon4-associated subtype of sporadic Alzheimer's disease2010
Professor Johannes Attems
Concordance between epidermal growth factor receptor status in primary non-small-cell lung cancer and metastases: a post-mortem study2010
Professor Johannes Attems
ErbB2/CEP17 and total ErbB2 copy number as independent forecast factor for time to First Metastasis (TTM) and with a trastuzumab-based therapy in HER2 testing metasase breast cancer [abstract]2010
Professor Johannes Attems
Expression of TAU in insulin-secreting cells and its interaction with the calcium-binding protein secretagogin2010
Professor Johannes Attems
Is there pure vascular dementia in old age?2010
Professor Johannes Attems
Is there pure vascular dementia in old age?2010
Professor Johannes Attems
Prevalence and pathology of vascular dementia in the oldest old2010
Professor Johannes Attems
Prevalence of dementia disorders in the oldest-old: an autopsy study2010
Professor Johannes Attems
[abstract] A 18-year-old Girl with Fever, Cough, and cystic Lesions in the Lungs2009
Professor Johannes Attems
[abstract] EGFR status of primary NSCLC remains unchanged in lymph node and organ metastases: An autopsy study2009
Professor Johannes Attems
[abstract] The abscess formation by Cryptococcus neoformans with underlying Sarcoide and distinct immunodeficiency2009
Professor Johannes Attems
Amyloid PET and MRI in Alzheimer's disease and mild cognitive impairment2009
Professor Johannes Attems
Different Neprilysin expression in vessels of occipital and frontal lobes2009
Professor Johannes Attems
Neuropathology of age-associated neurodegenerative diseases2009
Professor Johannes Attems
Neuropathology of Parkinson's disease dementia and dementia with Lewy bodies2009
Professor Johannes Attems
Sporadic cerebral amyloid angiopathy-No frequent cause of spontaneous brain hemorrhage in the aged2009
Professor Johannes Attems
Biomarkers for early diagnosis of Alzheimer disease: 'ALZheimer ASsociated gene'-a new blood biomarker?2008
Professor Johannes Attems
Calcium binding protein secretagogin and neuroprotection in Alzheimer's disease2008
Professor Johannes Attems
Calcium-binding protein secretagogin-expressing neurones in the human hippocampus are largely resistant to neurodegeneration in Alzheimer's disease2008
Professor Johannes Attems
Cerebral amyloid angiopathy in Lewy body disease2008
Professor Johannes Attems
Cerebral amyloid angiopathy in Lewy body disease2008
Professor Johannes Attems
Ewing's sarcoma and peripheral primitive neuroectodermal tumor in adults: different features of a rare neoplasm2008
Professor Johannes Attems
Neuropathology of Parkinson's disease Dementia (PDD) and Dementia with Lewy bodies (DLB)2008
Professor Johannes Attems
Prevalence and impact of vascular and Alzheimer pathologies in Lewy body disease2008
Professor Johannes Attems
Secretagogin is expressed in hippocampal neurones of wild type but not of tau-homocygote (P301L) mice2008
Professor Johannes Attems
The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease2008
Professor Johannes Attems
Unexpectedly low prevalence of intracerebral hemorrhages in sporadic cerebral amyloid angiopathy: an autopsy study2008
Professor Johannes Attems
Catheter-related Leuconostoc bacteremia secondary to pulmonary Mycobacterium xenopi infection2007
Professor Johannes Attems
Down-regulation of Sprouty2 in non-small cell lung cancer contributes to tumor malignancy via extracellular signal-regulated kinase pathway-dependent and -independent mechanisms2007
Professor Johannes Attems
Immunoreactivity of calcium binding protein secretagogin in the human hippocampus is restricted to pyramidal neurons2007
Professor Johannes Attems
Intratumoral IGF-I protein expression is selectively upregulated in breast cancer patients with BRCA1/2 mutations2007
Professor Johannes Attems
Mechanisms involved in the regulation of Sprouty4 expression2007
Professor Johannes Attems
Neurofibrillary tangle-predominant dementia: comparison with classical Alzheimer disease2007
Professor Johannes Attems
Neuropathological evaluation of mixed dementia2007
Professor Johannes Attems
Secretagogin expressing neurons in the human hippocampus are resistant to neurodegeneration in Alzheimer's disease2007
Professor Johannes Attems
Sporadic cerebral amyloid angiopathy is not a frequent cause of spontaneous brain hemorrhage2007
Professor Johannes Attems
Tau and alpha-synuclein brainstem pathology in Alzheimer disease: relation with extrapyramidal signs2007
Professor Johannes Attems
Topographical distribution of cerebral amyloid angiopathy and its effect on cognitive decline are influenced by Alzheimer disease pathology2007
Professor Johannes Attems
[abstract] Tau and alpha-syunclein brainstem lesions in Alzheimer disease2006
Professor Johannes Attems
Does striatal pathology distinguish Parkinson disease with dementia and dementia with Lewy bodies?2006
Professor Johannes Attems
Her-2/neu and EGFR tyrosine kinase activation predict the efficacy of trastuzumab-based therapy in patients with metastatic breast cancer2006
Professor Johannes Attems
Hippocampal sclerosis in Alzheimer disease and other dementias2006
Professor Johannes Attems
Intratumoral IGF-1 protein expression is selectively up-regulated in breast cancer patients with BRCA1/2 mutations2006
Professor Johannes Attems
Lung disease 35 years after aspiration of activated charcoal in combination with pulmonary lymphangioleiomyomatosis. A histological and clinicopathological study with scanning electron microscopic evaluation and element analysis2006
Professor Johannes Attems
Olfactory tau pathology in Alzheimer disease and mild cognitive impairment2006
Professor Johannes Attems
Prevalence and impact of cerebrovascular pathology in Alzheimer's disease and parkinsonism2006
Professor Johannes Attems
Tau and alpha-synuclein brainstem pathology in Alzheimer disease2006
Professor Johannes Attems
Alzheimer pathology in the olfactory bulb2005
Professor Johannes Attems
Alzheimer's disease pathology influences severity and topographical distribution of cerebral amyloid angiopathy2005
Professor Johannes Attems
Cause of death in demented and non-demented elderly inpatients; an autopsy study of 308 cases2005
Professor Johannes Attems
Expression of a piggy-back-gene determines Alzheimer disease pathology?2005
Professor Johannes Attems
Multidrug resistance markers P-glycoprotein, multidrug resistance protein 1, and lung resistance protein in non-small cell lung cancer: prognostic implications2005
Professor Johannes Attems
Olfactory involvement in ageing and Alzheimer disease2005
Professor Johannes Attems
Olfactory involvement in aging and Alzheimer's disease: an autopsy study2005
Professor Johannes Attems
Olfactory pathology in aging and Alzheimer disease2005
Professor Johannes Attems
Prevalence and pathogenic role of cerebrovascular lesions in Alzheimer disease2005
Professor Johannes Attems
Sporadic cerebral amyloid angiopathy: pathology, clinical implications, and possible pathomechanisms2005
Professor Johannes Attems
Tau and alpha-synuclein brainstem pathology in Alzheimer disease2005
Professor Johannes Attems
The efficacy of trastuzumab in Her-2/neu-overexpressing metastatic breast cancer is independent of p53 status2005
Professor Johannes Attems
[correction] Amyloid beta peptide 1-42 highly correlates with capillary cerebral amyloid angiopathy and Alzheimer disease pathology (vol 107, pg 283, 2004)2004
Professor Johannes Attems
A proteomic and immunhistochemical approach to the study of Alzheimer disease2004
Professor Johannes Attems
Active Her-2/neu signal transduction in breast cancer - relevance of a ligand-independent activation mechanism and impact an the efficacy of trastuzumab-based treatment2004
Professor Johannes Attems
Amyloid beta peptide 1-42 highly correlates with capillary cerebral amyloid angiopathy and Alzheimer disease pathology2004
Professor Johannes Attems
Only cerebral capillary amyloid angiopathy correlates with Alzheimer pathology-a pilot study2004
Professor Johannes Attems
Relations between cerebral amyloid angiopathy and Alzheimer's disease pathology2004
Professor Johannes Attems
The clinical diagnostic accuracy rate regarding the immediate cause of death in a hospitalized geriatric population; an autopsy study of 1594 patients2004
Professor Johannes Attems
Her-2/neu-triggered intracellular tyrosine kinase activation: in vivo relevance of ligand-independent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment2003
Professor Johannes Attems
Incidence of cerebrovascular lesions in Alzheimer's disease: a postmortem study2003
Professor Johannes Attems
Pseudomesotheliomatous adenocarcinoma of the lung with rhabdoid features2001