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Telomeres and cardiovascular diseases: Facts, controversies and limitations

Lookup NU author(s): Professor Ioakim Spyridopoulos

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Abstract

© 2017 by Taylor & Francis Group, LLC. Despite advances in diagnosis and treatment, CVD remains the major cause of morbidity and mortality in industrialized countries and is expected to become so worldwide by 2020. The economic, social and human costs associated with CVD treatment are immense. To improve diagnosis, prevention and treatment, it is thus urgent to refine classic CVD risk scores and identify new genetic, cellular and molecular mechanisms underlying disease initiation and early progression. This chapter examines advances in our understanding of the role of telomere shortening in the etiopathogenesis of CVD, and discusses limitations and perspectives for future research.


Publication metadata

Author(s): Andres V, Dorado B, Spyridopoulos I

Publication type: Book Chapter

Publication status: Published

Book Title: Mechanisms Linking Aging, Diseases and Biological Age Estimation

Year: 2017

Pages: 150-160

Print publication date: 21/12/2016

Online publication date: 27/03/2017

Acceptance date: 02/04/2016

Publisher: CRC Press

Place Published: Boca Raton, FL, USA

URL: https://doi.org/10.1201/9781315371382

DOI: 10.1201/9781315371382

Library holdings: Search Newcastle University Library for this item

ISBN: 9781498709705


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