Browse by author
Lookup NU author(s): Dr Louise HayesORCiD, Dr Lynne Forrest, Dr Jean Adams, Professor Martin White, Professor Linda Sharp
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
© Author(s) (or their employer(s)) 2018. No commercial re-use. See rights and permissions. Published by BMJ. Background: Older people experience poorer outcomes from colon cancer. We examined if treatment for colon cancer was related to age and if inequalities changed over time. Methods: Data from the UK population-based Northern and Yorkshire Cancer Registry on 31 910 incident colon cancers (ICD10 C18) diagnosed between 1999-2010 were obtained. Likelihood of receipt of: (1) cancer-directed surgery, (2) chemotherapy in surgical patients, (3) chemotherapy in non-surgical patients by age, adjusting for sex, area deprivation, cancer stage, comorbidity and period of diagnosis, was examined. Results: Age-related inequalities in treatment exist after adjustment for confounding factors. Patients aged 60- 69, 70-79 and 80+ years were significantly less likely to receive surgery than those aged <60 years (multivariable ORs (95% CI) 0.84(0.74 to 0.95), 0.54(0.48 to 0.61) and 0.19(0.17 to 0.21), respectively). Age-related differences in receipt of surgery and adjuvant chemotherapy (but not chemotherapy in non-surgical patients) narrowed over time for the 'younger old' (aged <80 years) but did not diminish for the oldest patients. Conclusions: Age inequality in treatment of colon cancer remains after adjustment for confounders, suggesting age remains a major factor in treatment decisions. Research is needed to better understand the cancer treatment decision-making process, and how to influence this, for older patients.
Author(s): Hayes L, Forrest L, Adams J, Hidajat M, Ben-Shlomo Y, White M, Sharp L
Publication type: Article
Publication status: Published
Journal: Journal of Epidemiology and Community Health
Year: 2018
Volume: 73
Issue: 1
Pages: 34-41
Print publication date: 11/12/2018
Online publication date: 08/11/2018
Acceptance date: 31/07/2018
ISSN (print): 0143-005X
ISSN (electronic): 1470-2738
Publisher: BMJ Publishing Group
URL: .https:/doi.org/10.1136/jech-2018-210842
DOI: 10.1136/jech-2018-210842
Altmetrics provided by Altmetric
