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β-Cell and renal transplantation options for diabetes

Lookup NU author(s): Dr Anneliese Flatt, Steven White, Professor James Shaw


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© 2019 Diabetes UK. Despite major advances in structured education, insulin delivery and glucose monitoring, diabetes self-management remains an unremitting challenge. Insulin therapy is inextricably linked to risk of dangerous hypoglycaemia and sustained hyperglycaemia remains a leading cause of renal failure. This review sets out to demystify transplantation for diabetes multidisciplinary teams, facilitating consideration and incorporation within holistic overall person-centred management. Deceased and living donor kidney, whole pancreas and isolated islet transplant procedures, indications and potential benefits are described, in addition to outcomes within the integrated UK transplant programme.

Publication metadata

Author(s): Flatt AJS, Bennett D, Counter C, Brown AL, White SA, Shaw JAM

Publication type: Review

Publication status: Published

Journal: Diabetic Medicine

Year: 2019

Volume: 37

Issue: 4

Pages: 580-592

Print publication date: 01/04/2020

Online publication date: 08/11/2019

Acceptance date: 07/11/2019

ISSN (print): 0742-3071

ISSN (electronic): 1464-5491

Publisher: Blackwell Publishing Ltd


DOI: 10.1111/dme.14177

PubMed id: 31705689