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The effects of a high-protein diet on markers of muscle damage following exercise in active older adults: A randomized, controlled trial

Lookup NU author(s): Tom Clifford, Ellie Hayes, Jadine Scragg, Guy Taylor, Kieran Smith, Dr Kelly Bowden Davies, Professor Emma Stevenson


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© 2020 Human Kinetics, Inc.Purpose: This study examined whether a higher protein diet following strenuous exercise can alter markers of muscle damage and inflammation in older adults. Methods: Using a double-blind, independent group design, 10 males and eight females (age 57 ± 4 years; mass 72.3 ± 5.6 kg; height 1.7 ± 6.5 m) were supplied with a higher protein (2.50 g·kg−1·day−1) or moderate protein (1.25 g·kg−1·day−1) diet for 48 hr after 140 squats with 25% of their body mass. Maximal isometric voluntary contractions, muscle soreness, creatine kinase, Brief Assessment of Mood Adapted, and inflammatory markers were measured preexercise, and 24 hr and 48 hr postexercise. Results: The maximal isometric voluntary contractions decreased postexercise (p = .001, η2p = .421), but did not differ between groups (p = .822, η2p = .012). Muscle soreness peaked at 24 hr post in moderate protein (44 ± 30 mm) and 48 hr post in higher protein (70 ± 46 mm; p = .005; η2p = .282); however, no group differences were found (p = .585; η2p = .083). Monocytes and lymphocytes significantly decreased postexercise, and eosinophils increased 24 hr postexercise (p < 0.05), but neutrophils, creatine kinase, interleukin-6, C-reactive protein, monocyte chemotactic protein-1, and Brief Assessment of Mood Adapted were unchanged by exercise or the intervention (p > .05). Conclusion: In conclusion, 2.50 g·kg−1·day−1 of protein is not more effective than 1.25 g·kg−1·day−1 for attenuating indirect markers of muscle damage and inflammation following strenuous exercise in older adults.

Publication metadata

Author(s): Clifford T, Hayes EJ, Scragg JH, Taylor G, Smith K, Bowden Davies KA, Stevenson EJ

Publication type: Article

Publication status: Published

Journal: International Journal of Sport Nutrition and Exercise Metabolism

Year: 2020

Volume: 30

Issue: 5

Pages: 323-329

Online publication date: 01/11/2020

Acceptance date: 02/04/2016

ISSN (print): 1526-484X

ISSN (electronic): 1543-2742

Publisher: Human Kinetics Publishers Inc.


DOI: 10.1123/IJSNEM.2020-0113

PubMed id: 32698121


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