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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).
Increased left ventricular mass index (LVMI) is associated with mortality in end-stage renal disease. LVMI regression may improve outcomes. Allopurinol has reduced LVMI in randomized controlled trials in chronic kidney disease, diabetes, and ischemic heart disease. This study investigated whether allopurinol would regress LVMI in hemodialysis patients.
Author(s): Rutherford E, Ireland S, Mangion K, Stewart GA, MacGregor MS, Roditi G, Woodward R, Gandy SJ, Houston JG, Jardine AG, Rauchhaus P, Witham MD, Mark PB, Struthers AD
Publication type: Article
Publication status: Published
Journal: Kidney International Reports
Year: 2021
Volume: 6
Issue: 1
Pages: 146-155
Print publication date: 01/01/2021
Online publication date: 03/12/2020
Acceptance date: 02/10/2020
Date deposited: 13/12/2020
ISSN (electronic): 2468-0249
Publisher: Elsevier Inc.
URL: https://doi.org/10.1016/j.ekir.2020.10.025
DOI: 10.1016/j.ekir.2020.10.025
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