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Browsing publications by Professor Miles Witham.

Newcastle AuthorsTitleYearFull text
Dr Claire McDonald
Matt Birkbeck
Dr Silvia Del Din
Dr Gráinne Gorman
Dr Kieren Hollingsworth
et al.
A study protocol to investigate if Acipimox improves muscle function and sarcopenia –an open-label, uncontrolled, before-and-after experimental medicine feasibility study in community dwelling older adults.2024
Dr Sue Bellass
Professor Thomas Scharf
Linda Errington
Dr Kelly Bowden Davies
Professor Miles Witham
et al.
Experiences of hospital care for people with multiple long-term conditions: a scoping review of qualitative research2024
Dr Chris Plummer
Professor Avan Sayer
Professor Miles Witham
How far back do we need to look to capture diagnoses in electronic health records? A retrospective observational study of hospital electronic health record data2024
Professor Avan Sayer
Professor Miles Witham
Nutritional screening, initial management and referral for older people with sarcopenia or frailty - results from a UK-wide survey2024
Professor Rachel Cooper
Dr Jonny Bunn
Dr Sarah Richardson
Susan Hillman
Professor Avan Sayer
et al.
Rising to the challenge of defining and operationalising multimorbidity in a UK hospital setting: the ADMISSION research collaborative2024
Dr Lorna Caulfield
Dr Philip Heslop
Dr Christopher Hurst
Professor Avan Sayer
Professor Miles Witham
et al.
The Benchmarking Exercise Programme for Older People (BEPOP): design, results and recommendations from the first wave of data collection2024
Dr Terry Aspray
Dr Gordon Duncan
Dr Simon Kerr
Professor Avan Sayer
Professor Miles Witham
et al.
ACE I/D genotype associates with strength in sarcopenic men but not with response to ACE inhibitor therapy in older adults with sarcopenia: Results from the LACE trial2023
Dr Terry Aspray
Dr Gordon Duncan
Dr Simon Kerr
Professor Avan Sayer
Professor Miles Witham
et al.
Activin type I receptor polymorphisms and body composition in older individuals with sarcopenia—Analyses from the LACE randomised controlled trial2023
Dr Antoneta Granic
Dr Christopher Hurst
Lorelle Dismore
Dr Richard Dodds
Professor Miles Witham
et al.
Advanced glycation end products in skeletal muscle health and sarcopenia: A systematic review of observational studies2023
Dr Christopher Hurst
Lorelle Dismore
Dr Antoneta Granic
Dr Ellen Tullo
Dr Jane Noble
et al.
Attitudes and barriers to resistance exercise training for older adults living with multiple long-term conditions, frailty, and a recent deterioration in health: Qualitative findings from the Lifestyle in Later Life – Older People’s Medicine (LiLL-OPM) study2023
Lou Whitehead
Professor Miles Witham
Professor James Wason
Bayesian borrowing for basket trials with longitudinal outcomes2023
Professor Miles Witham
Co-design of a behaviour change intervention to equip geriatricians and pharmacists to proactively deprescribe medicines that are no longer needed or are risky to continue in hospital2023
Professor Miles Witham
CompreHensive geriAtRician-led MEdication Review (CHARMER): Protocol for a feasibility study of a hospital deprescribing behaviour change intervention2023
Professor Avan Sayer
Professor Miles Witham
Development of a UK core dataset for geriatric medicine research: a position statement and results from a Delphi consensus process2023
Dr Christopher Hurst
Lorelle Dismore
Dr Antoneta Granic
Dr Ellen Tullo
Dr Jane Noble
et al.
Feasibility of engaging older adults living with multiple long-term conditions, frailty, and a recent deterioration in health in a study of lifestyle: protocol for the LiLL-OPM study2023
Dr Claire McDonald
Professor Rachel Cooper
Professor Avan Sayer
Professor Miles Witham
Improving care for patients with multiple long-term conditions admitted to hospital – challenges and potential solutions British Journal of Hospital Medicine2023
Professor Miles Witham
Including older people in health and social care research: best practice recommendations based on the INCLUDE framework2023
Professor Miles Witham
Increasing physical activity levels in care homes for older people: a quantitative scoping review of intervention studies to guide future research2023
Fearnley Evison
Professor Rachel Cooper
Professor Paolo Missier
Professor Avan Sayer
Professor Miles Witham
et al.
Mapping inpatient care pathways for patients with COPD: an observational study using routinely-collected electronic hospital record data2023
Professor Anthony De Soyza
Professor Miles Witham
Multimorbidity in bronchiectasis: a systematic scoping review2023
Professor Miles Witham
Dr Antoneta Granic
Dr Satomi Miwa
Dr Gavin Richardson
Professor Avan Sayer
et al.
New Horizons in cellular senescence for clinicians2023
Mo Osman
Professor Miles Witham
Professor Avan Sayer
Professor Rachel Cooper
Optimising the use of SARC-F for the identification of muscle weakness by considering alternative cut-points: findings from the Newcastle SarcScreen project2023
Professor Miles Witham
Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study2023
Dr Christopher Hurst
Professor Avan Sayer
Professor Miles Witham
Remote collection of physical performance measures for older people: a systematic review2023
Professor Miles Witham
Dr Antoneta Granic
Professor Sian Robinson
Professor Avan Sayer
Repurposing drugs for diabetes mellitus as potential pharmacological treatments for sarcopenia – a narrative review2023
Professor Miles Witham
Professor Rachel Cooper
Professor Paolo Missier
Professor Sian Robinson
Professor Avan Sayer
et al.
Researching multimorbidity in hospital: can we deliver on the promise of health informatics?2023
Dr Richard Dodds
Dr Jonny Bunn
Susan Hillman
Dr Antoneta Granic
James Murray
et al.
Simple approaches to characterising multiple long-term conditions (multimorbidity) and rates of emergency hospital admission: Findings from 495,465 UK Biobank participants2023
Professor Miles Witham
Professor Lynn Rochester
Professor Avan Sayer
Spotlight on the academic multidisciplinary team: proposals from the 3rd NIHR Newcastle BRC Academic Geriatric Medicine Workshop2023
Dr Tamer El-Sayed
Dilraj Bhullar
Lauren Shelmerdine
Professor Miles Witham
Professor Gerard Stansby
et al.
The role of Braden scores in predicting outcomes following revascularisation for chronic limb threatening ischaemia and their association with frailty2023
Michael Reed
Professor Avan Sayer
Professor Miles Witham
Dr Tony Sorial
Using pre-fracture mobility to augment prediction of post-operative outcomes in hip fracture2023
Lorelle Dismore
Dr Christopher Hurst
Dr Antoneta Granic
Dr Ellen Tullo
Professor Miles Witham
et al.
Why are older adults living with the complexity of multiple long-term conditions, frailty and a recent deterioration in health under-served by research? A narrative synthesis review of the literature2023
Professor Miles Witham
Professor Rachel Cooper
Dr Kelly Bowden Davies
Professor Avan Sayer
Ageing Research Translation: a new era for UK geroscience2022
Professor Miles Witham
Professor Rachel Cooper
Dr Kelly Bowden Davies
Professor Teresa Orta Ledesma
Professor Avan Sayer
et al.
Ageing Research Translation: a new era for UK Geroscience2022
Professor Miles Witham
Cardiovascular disease risk profile and management among people 40 years of age and above in Bo, Sierra Leone: A cross-sectional study2022
Professor Rachel Cooper
Professor Miles Witham
Professor Avan Sayer
Defining and measuring multiple long term conditions in research2022
Professor Miles Witham
Developing a core outcome set for hospital deprescribing trials for older people under the care of a geriatrician2022
Dr Terry Aspray
Dr Simon Kerr
Professor Avan Sayer
Professor Miles Witham
Effect of Perindopril or Leucine on physical performance in older people with sarcopenia: the LACE randomised controlled trial2022
Dr Fred Barker
Adam Hart
Professor Avan Sayer
Professor Miles Witham
Effects of nicotinamide adenine dinucleotide precursors on measures of physical performance and physical frailty: A systematic review2022
Professor Miles Witham
Erratum: Correction: Trial Forge Guidance 3: randomised trials and how to recruit and retain individuals from ethnic minority groups-practical guidance to support better practice2022
Professor Miles Witham
Exploring the lived experience of renal cachexia for individuals with end-stage renal disease and the interrelated experience of their carers: Study protocol2022
Dr Jake Gibbon
Dr Steve Parry
Professor Miles Witham
Professor Alison Yarnall
Dr James Frith
et al.
Feasibility, reliability and safety of self-assessed orthostatic blood pressure at home2022
Dr Kate Rennie
Professor Miles Witham
Penny Bradley
Professor Helen Hancock
Shaun Hiu
et al.
MET-PREVENT: metformin to improve physical performance in older people with sarcopenia and physical prefrailty/frailty - protocol for a double-blind, randomised controlled proof-of-concept trial2022
Professor Ngaire Kerse
Professor Miles Witham
New horizons in evidence-based care for older people: individual participant data meta-analysis2022
Professor Miles Witham
Dr Philip Heslop
Dr Richard Dodds
Dr Claire McDonald
Bryony Storey
et al.
Performance of the SarQoL quality of life tool in a UK population of older people with probable sarcopenia and implications for use in clinical trials: findings from the SarcNet Registry2022
Dr Christopher Hurst
Professor Sian Robinson
Professor Miles Witham
Dr Richard Dodds
Dr Antoneta Granic
et al.
Resistance exercise as a treatment for sarcopenia: prescription and delivery2022
Dr Richard Dodds
Dr Karen Davies
Dr Jane Noble
Dr Fiona Shaw
Professor Miles Witham
et al.
The assessment of sarcopenia and the frailty phenotype in the outpatient care of older people: implementation and typical values obtained from the Newcastle SarcScreen project2022
Dr Justin Presseau
Professor Miles Witham
The development of theory-informed participant-centred interventions to maximise participant retention in randomised controlled trials2022
Professor Miles Witham
Trial Forge Guidance 3: randomised trials and how to recruit and retain individuals from ethnic minority groups—practical guidance to support better practice2022
Professor Miles Witham
A randomized, controlled trial of the effect of allopurinol on left ventricular mass index in hemodialysis patients2021
Dr Sarah Richardson
Professor Miles Witham
Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study2021
Professor Miles Witham
Association between mitochondrial function measured by 31P Magnetic Resonance Spectroscopy and physical performance in older people with functional impairment2021
Professor Miles Witham
Associations between Frailty, Physical Performance, and Renal Biomarkers in Older People with Advanced Chronic Kidney Disease2021
Professor Miles Witham
Dr Patricia Kearney
Barriers and potential solutions in the recruitment and retention of older patients in clinical trials—lessons learned from six large multicentre randomized controlled trials2021
Professor Miles Witham
Dr Philip Heslop
Dr Richard Dodds
Dr Claire McDonald
Bryony Storey
et al.
Developing a UK sarcopenia registry: recruitment and baseline characteristics of the SarcNet pilot2021
Dr Fred Barker
Professor Fiona Matthews
Professor Richard Walker
Professor Miles Witham
Developing and evaluating a Frailty Index for older South Africans – findings from the HAALSI study2021
Irene Soulsby
Professor Miles Witham
Developing the INCLUDE Ethnicity Framework - a tool to help trialists design trials that better reflect the communities they serve2021
Dr Lorna Caulfield
Dr Philip Heslop
Professor Avan Sayer
Professor Miles Witham
Effect of Angiotensin System Inhibitors on Physical Performance in Older People – A Systematic Review and Meta-Analysis2021
Professor Miles Witham
Effect of multiple episodes of acute kidney injury on mortality: an observational study2021
Dr Rachel Stocker
Professor James Shaw
Dr Guy Taylor
Professor Miles Witham
Dr Daniel West
et al.
EXercise to Prevent frailty and Loss Of independence in insulin treated older people with DiabetEs (EXPLODE): protocol for a feasibility randomised controlled trial (RCT)2021
Professor Miles Witham
Dr Richard Dodds
Hip fracture and sarcopenia – the need for a new paradigm in therapeutics trials for older people?2021
Professor Miles Witham
Impairment in Activities of Daily Living and Unmet Need for Care Among Older Adults: A Population-Based Study From Burkina Faso2021
Professor Avan Sayer
Professor Miles Witham
Dr Tony Sorial
Implementing grip strength assessment in hip fracture patients: a feasibility project2021
Professor Miles Witham
Multimorbidity and mortality in an older, rural Black South African population cohort with high prevalence of HIV-findings from the HAALSI study2021
Professor Sheena Ramsay
Dr Antoneta Granic
Dr Christopher Hurst
Dr Nuno Mendonca
Esme Tuttiett
et al.
Nutrition and Frailty: Opportunities for Prevention and Treatment2021
Professor Miles Witham
Pandemic research for older people: doing it better next time2021
Michael Reed
Professor Avan Sayer
Professor Miles Witham
Dr Tony Sorial
Prediction of postoperative outcomes after hip fracture surgery: independent validation and recalibration of the Nottingham Hip Fracture Score2021
Professor Miles Witham
Prevalence and socio-demographic associations of diet and physical activity risk-factors for cardiovascular disease in Bo, Sierra Leone2021
Professor Miles Witham
Dr Terry Aspray
Professor Avan Sayer
Recruitment strategies for sarcopenia trials: lessons from the LACE randomized controlled trial2021
Professor Miles Witham
Research into ageing and frailty2021
Dr Ashwin Sivaharan
Dr Luke Boylan
Professor Miles Witham
Dr Sandip Nandhra
Sarcopenia in patients undergoing lower limb bypass surgery is associated with higher mortality and major amputation rates2021
Professor Miles Witham
The ViKTORIES trial: a randomised, double-blind, placebo-controlled trial of vitamin K supplementation to improve vascular health in kidney transplant recipients2021
Professor Miles Witham
Using a generic definition of cachexia to understand clinical characteristics and mortality in patients with kidney disease receiving haemodialysis: a longitudinal (pilot) study2021
Dr Matthew Bolland
Professor Miles Witham
Vitamin D supplementation and testing in the UK: costly but ineffective?2021
Professor Miles Witham
Vitamin K and vascular calcification2021
Dr Justin Presseau
Dr Jill Francis
Professor Miles Witham
Why trials lose participants: a multi-trial investigation of participants’ perspectives using the theoretical domains framework2021
Professor Miles Witham
An innovative model for management of cardiovascular disease risk factors in the low resource setting of Cambodia2020
Professor Miles Witham
Association between the use of Angiotensin-blocking medications with hip fracture and death in older people2020
Professor Miles Witham
Carotid intima-media thickness progression as surrogate marker for cardiovascular risk: Meta-analysis of 119 clinical trials involving 100,667 patients2020
Professor Miles Witham
Dr Karthik Balasubramaniam
Clinical and cost-effectiveness of oral sodium bicarbonate therapy for older patients with chronic kidney disease and low-grade acidosis (BiCARB): a pragmatic, randomised, double-blind, placebo-controlled trial.2020
Professor Miles Witham
Professor Avan Sayer
Content of exercise programmes targeting older people with sarcopenia or frailty – findings from a UK survey2020
Professor Miles Witham
Depressive symptoms and cardiovascular disease: a population-based study of older adults in rural Burkina Faso2020
Professor Miles Witham
Professor James Wason
Dr Richard Dodds
Professor Avan Sayer
Developing a composite outcome measure for frailty prevention trials – rationale, derivation and sample size comparison with other candidate measures2020
Professor Miles Witham
Ella Anderson
Kimberley Down
Rebecca Maier
Dr Gary Nestor
et al.
Developing a roadmap to improve trial delivery for under-served groups: results from a UK multi-stakeholder process2020
Professor Miles Witham
Development and external validation of an acute kidney injury risk score for use in the general population2020
Professor Miles Witham
Paul McNamee
Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis? A multicentre randomized placebo controlled trial2020
Professor Miles Witham
Effect of Allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function – a randomised controlled trial2020
Professor Miles Witham
Ella Anderson
Kimberley Down
Rebecca Maier
Dr Gary Nestor
et al.
Ensuring that COVID-19 research is inclusive: guidance from the NIHR INCLUDE project2020
Sarah Moore
Nina Hrisos
Linda Errington
Professor Lynn Rochester
Emerita Professor Helen Rodgers
et al.
Exercise as a treatment for sarcopenia; An umbrella review of systematic review evidenc2020
Professor Miles Witham
Frailty and physical performance in the context of extreme poverty: a population-based study of older adults in rural Burkina Faso2020
Professor Miles Witham
Impairment in activities of daily living, care receipt and unmet needs in a middle-aged and older rural South African population: findings from the HAALSI study2020
Professor Miles Witham
Knowledge and understanding of cardiovascular disease risk factors in Sierra Leone: a qualitative study of patients' and community leaders' perceptions2020
Dr Philip Heslop
Dr Karen Davies
Professor Avan Sayer
Professor Miles Witham
Making consent for electronic health and social care data research fit for purpose in the 21st century2020
Dr Antoneta Granic
Dr Christopher Hurst
Lorelle Dismore
Dr Terry Aspray
Professor Emma Stevenson
et al.
Milk for skeletal muscle health and sarcopenia in older adults: a narrative review2020
Professor Miles Witham
John Davies
Prevalence and access to care for cardiovascular risk factors in older people in Sierra Leone: a cross-sectional survey2020
Professor Miles Witham
Quality of life in advanced renal disease managed either by haemodialysis or conservative care in older patients2020
Dr Sarah Richardson
Professor John O'Brien
Professor Lynn Rochester
Professor Avan Sayer
Professor Miles Witham
et al.
Research with older people in a world with COVID-19: identification of current and future priorities, challenges and opportunities2020
Professor Miles Witham
Self-reported physical activity in middle-aged and older adults in rural South Africa: levels and correlates2020
Professor Miles Witham
Paul McNamee
Sodium bicarbonate to improve physical function in patients over 60 years with advanced chronic kidney disease: the BiCARB RCT2020
Professor Miles Witham
Tackling immunosenescence to improve COVID-19 outcomes and vaccine response in older adults2020
Professor Miles Witham
The COVID-19 Rehabilitation Pandemic2020
Professor Miles Witham
The epidemiology of multimorbidity in conditions of extreme poverty: a population-based study of older adults in rural Burkina Faso2020
Dr Naweed Sattar
Professor Miles Witham
The Prospective Studies of Atherosclerosis (Proof-ATHERO) consortium: Design and rationale2020
Professor Miles Witham
Vitamin K for kidney transplant Organ Recipients: investigating vEssel Stiffness (ViKTORIES): Study rationale and protocol of a randomised controlled trial2020
Professor Miles Witham
Vitamin K supplementation to improve vascular stiffness in chronic kidney disease - the K4Kidneys randomised controlled trial2020
Professor Miles Witham
A new dawn for sarcopenia2019
Professor Miles Witham
Ability of verbal autopsy data to detect deaths due to uncontrolled hyperglycaemia: testing existing methods and development and validation of a novel weighted score2019
Professor Miles Witham
Bridging the gap between the laboratory and the clinic for patients with sarcopenia2019
Professor Miles Witham
Clinical research methods for studies of older people2019
Dr Richard Dodds
Professor Avan Sayer
Professor Miles Witham
Current practice in the diagnosis and management of sarcopenia and frailty – results from a UK-wide survey2019
Professor Miles Witham
Effect of vitamin K2 on postural sway in older people who fall: a randomised controlled trial2019
Professor Miles Witham
Professor Avan Sayer
Growing research in geriatric medicine2019
Professor Miles Witham
Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure: Individual Participant Meta-Analysis2019
Professor Miles Witham
Impact of exercise-based rehabilitation in patients with heart failure (ExTraMATCH II) on exercise capacity and health-related quality of life: a meta-analysis of individual participant data from randomised trials 2019
Professor Miles Witham
Oral Bicarbonate Therapy in Non-Haemodialysis Dependent Chronic Kidney Disease Patients: A Systematic Review and Meta-Analysis of Randomised Controlled Trials2019
Professor Miles Witham
Serum sodium level variability as a prognosticator in older adults2019
Dr Catherine Douglas
Professor Miles Witham
The impact of a renal support care service on symptom control, advance care planning and place of death for patients with advanced chronic kidney disease managed without dialysis2019
Professor Miles Witham
Variability in the clinical management of iron-deficiency anaemia in older adults: results from a survey of UK specialists in the care of older people2019
Professor Miles Witham
Vitamin K status, supplementation and vascular disease: A systematic review and meta-analysis2019
Professor Miles Witham
Acceptability and feasibility of magnetic femoral nerve stimulation in older, functionally impaired patients.2018
Professor Falko Sniehotta
Professor Miles Witham
Association Between Objectively Measured Physical Activity and Opioid, Hypnotic, or Anticholinergic Medication Use in Older People: Data from the Physical Activity Cohort Scotland Study2018
Professor Miles Witham
Causes and correlates of 30 day and 180 day readmission following discharge from a Medicine for the Elderly Rehabilitation unit2018
Professor Miles Witham
Collaboration for impact in global health2018
Professor Miles Witham
Cross-sectional relationship between haemoglobin concentration and measures of physical and cognitive function in an older rural South African population2018
Professor Miles Witham
Effect of two different participant information sheets on recruitment to a falls trial: an embedded randomised recruitment trial2018
Professor Miles Witham
Effect of Vitamin D Supplementation on Markers of Vascular Function: A Systematic Review and Individual Participant Meta-Analysis2018
Professor Miles Witham
Leucine and ACE inhibitors as therapies for sarcopenia (LACE trial): study protocol for a randomised controlled trial2018
Professor Miles Witham
Variations in disability and quality of life with age and sex between eight lower and middle-income countries: data from the INDEPTH WHO-SAGE collaboration2017
Professor Miles Witham
Effect of vitamin D supplementation on blood pressure: a systematic review and meta-analysis incorporating individual patient data2015
Dr Paul Gellert
Professor Miles Witham
Professor Falko Sniehotta
The role of perceived barriers and objectively measured physical activity in adults aged 65-1002015
Professor Miles Witham
Professor Avan Sayer
ACE inhibitors, statins and thiazides: no association with change in grip strength among community dwelling older men and women from the Hertfordshire Cohort Study2014
Professor Miles Witham
Professor Falko Sniehotta
Association of Day Length and Weather Conditions with Physical Activity Levels in Older Community Dwelling People2014
Professor Miles Witham
Vitamin D therapy to reduce blood pressure and left ventricular hypertrophy in resistant hypertension: randomised, controlled trial2014
Professor Falko Sniehotta
Dr Paul Gellert
Professor Miles Witham
Psychological theory in an interdisciplinary context: psychological, demographic, health-related, social, and environmental correlates of physical activity in a representative cohort of community-dwelling older adults2013
Professor Falko Sniehotta
Professor Miles Witham
Social, Environmental and Psychological Factors Associated with Objective Physical Activity Levels in the Over 65s2012