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Lookup NU author(s): Dr Arthur PrattORCiD, Professor John IsaacsORCiD, Dr Elena Nikiphorou
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© 2021 The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com.This systematic literature review aimed to analyse terms describing coexisting conditions in the RA literature, informing the need for an operationalized definition of multimorbidity. Articles discussing RA with multimorbidity, published 1946 until August 2020, were identified. The primary outcome was the use and/or definition of 'multimorbidity' in RA. Information extracted included terms defining coexisting conditions, the use of a comorbidity/multimorbidity score and the use of 'index disease' to describe RA (more applicable to comorbidity than multimorbidity). Thirty-nine articles were included. Eight articles used the term 'multimorbidity', 18 used 'comorbidity' and 12 used both terms, 7 synonymously. One used no term. Fourteen articles fully defined the term. The number of co-existing conditions described in included studies was one-121. Twelve articles used a comorbidity/multimorbidity score. Four articles described RA as the 'index disease'. Our results demonstrate inconsistent use of the term multimorbidity. Improved assessment of multimorbidity is indicated in RA patients, including an operationalized use and definition.
Author(s): Dey M, Busby A, Elwell H, Pratt A, Young A, Isaacs J, Nikiphorou E
Publication type: Review
Publication status: Published
Journal: Rheumatology
Year: 2021
Volume: 60
Issue: 7
Pages: 3058-3071
Print publication date: 01/07/2021
Online publication date: 03/03/2021
Acceptance date: 20/02/2021
ISSN (print): 1462-0324
ISSN (electronic): 1462-0332
Publisher: Oxford University Press
URL: https://doi.org/10.1093/rheumatology/keab214
DOI: 10.1093/rheumatology/keab214
PubMed id: 33682885
