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Overactive mitochondrial DNA replication disrupts perinatal cardiac maturation

Lookup NU author(s): Dr Jim StewartORCiD

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Author(s): Landoni JC, Erkul S, Laalo T, Goffart S, Kivela R, Skube K, Jokitalo E, Nieminen A, Wickstrom S, Stewart J, Suomalainen A

Publication type: Article

Publication status: Published

Journal: Nature Communications

Year: 2024

Volume: 15

Online publication date: 14/09/2024

Acceptance date: 28/08/2024

Date deposited: 15/09/2024

ISSN (electronic): 2041-1723

Publisher: Nature Publishing Group

URL: https://www.nature.com/articles/s41467-024-52164-1

DOI: 10.1038/s41467-024-52164-1

Data Access Statement: All data generated or analyzed during this study are included in this published article, its supplementary files, source data, or available in the following repositories: Sequencing data have been deposited at the NCBI SRA database; accession: PRJNA830670. The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PXD047603. Other supplementary data including the detailed results of the omics analyzes and representative videos of echocardiograms can be found in the Mendeley Data repository with the identifier https://doi.org/10.17632/wm2dhwpghm.145. Source data are provided with this paper.

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