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MALDI-TOF mass spectrometry in the 21st century

Lookup NU author(s): Dr Maria Duenas FadicORCiD, Professor Matthias TrostORCiD



This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).


© The Authors. Published by Portland Press Limited under the Creative Commons Attribution License 4.0 (CC BY-NC-ND)This year marks the 20th anniversary of Koichi Tanaka securing the Nobel Prize in chemistry, shared with John Fenn and Kurt Wüthrich, for demonstrating the applicability of laser technology to analyze biological macromolecules. The principle of laser desorption is fundamental for many of today’s analytical methods such as matrix-assisted laser desorption/ionization (MALDI). In this article, we provide an overview of MALDI and highlight the power, versatility and range of applications within the biochemistry community.

Publication metadata

Author(s): Duenas ME, Trost M

Publication type: Article

Publication status: Published

Journal: Biochemist

Year: 2022

Volume: 44

Issue: 5

Pages: 2-4

Online publication date: 27/10/2022

Acceptance date: 02/04/2018

Date deposited: 28/11/2022

ISSN (print): 0954-982X

ISSN (electronic): 1740-1194

Publisher: Portland Press Ltd


DOI: 10.1042/bio_2022_130


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