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Browsing publications by Professor Matthias Trost.

Newcastle AuthorsTitleYearFull text
Dr Olivier Govaere
Dr Rebecca Darlay
Dr Julien Peltier
Dr Jeremy Palmer
Dr Massimo Younes
et al.
Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease2022
Dr Marzena Kurzawa-Akanbi
Rachel Heap
Professor Matthias Trost
Dr Preeti Singh
Dr Florence Burte
et al.
Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body disorders2021
Dr Akshada Gajbhiye
Professor Matthias Trost
Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes2021
Catherine Hatton
Dr Rachel Botting
Dr Maria Duenas Fadic
Dr Iram Haq
Dr Bernard Verdon
et al.
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-22021
Rachel Heap
Dr Jose Marin Rubio
Dr Julien Peltier
Dr Tiaan Heunis
Dr Abeer Dannoura
et al.
Proteomics characterisation of the L929 cell supernatant and its role in BMDM differentiation2021
Dr Julien Peltier
Dr Tiaan Heunis
Professor Matthias Trost
TPL-2 kinase induces phagosome acidification to promote macrophage killing of bacteria2021
Dr Fatima Ulhuq
Dr Chriselle Mendonca
Dr Grant Buchanan
Dr Henrik Strahl von Schulten
Professor Matthias Trost
et al.
A membrane-depolarizing toxin substrate of the Staphylococcus aureus Type VII secretion system mediates intra-species competition2020
Dr Jack Leslie
Dr Marina Garcia Macia
Dr Saimir Luli
Dr Julie Worrell
William Reilly
et al.
c-Rel orchestrates energy-dependant epithelial and macrophage reprogramming in fibrosis2020
Professor Matthias Trost
High-throughput matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry–based deubiquitylating enzyme assay for drug discovery2020
Dr Tiaan Heunis
Professor Matthias Trost
Investigating Non-sterilizing Cure in TB Patients at the End of Successful Anti-TB Therapy2020
Dr Tiaan Heunis
Dr Frederic Lamoliatte
Dr Jose Marin Rubio
Dr Abeer Dannoura
Professor Matthias Trost
et al.
Technical report: Targeted proteomic analysis reveals enrichment of atypical ubiquitin chains in contractile murine tissues2020
Dr Akshada Gajbhiye
Professor Matthias Trost
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation2020
Dr Alan Cartmell
Dr Jose Munoz Munoz
Dr Jonathan Briggs
Dr Didier Ndeh
Dr Elisabeth Lowe
et al.
Author Correction: A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation2019
Professor Matthias Trost
Macrophage phosphoproteome analysis reveals MINCLE-dependent and-independent mycobacterial cord factor signaling2019
Nazma Malik
Dr Julien Peltier
Robert Gourlay
Professor Matthias Trost
Phosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR442019
Rachel Heap
Dr Alasdair Blain
Professor Matthias Trost
Profiling embryonic stem cell differentiation by MALDI TOF mass spectrometry: Development of a reproducible and robust sample preparation workflow2019
Dr Paul Dean
Dr Tiaan Heunis
Professor Matthias Trost
Regulation of phagosome functions by post-translational modifications: a new paradigm2019
Dr Julien Peltier
Professor Matthias Trost
Spatiotemporal Changes of the Phagosomal Proteome in Dendritic Cells in Response to LPS Stimulation2019
Professor Matthias Trost
Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages2019
Professor Matthias Trost
Unanchored tri-NEDD8 inhibits PARP-1 to protect from oxidative stress-induced cell death2019
Dr Alan Cartmell
Dr Jose Munoz Munoz
Dr Jonathan Briggs
Dr Didier Ndeh
Dr Elisabeth Lowe
et al.
A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status forarabinogalactan degradation2018
Dr Julien Peltier
Professor Matthias Trost
Activity-dependent bulk endocytosis proteome reveals a key presynaptic role for the monomeric GTPase Rab112018
Professor Matthias Trost
Inhibiting Multiple Deubiquitinases to Reduce Androgen Receptor Expression in Prostate Cancer Cells2018
Dr Giusy Mariano
Dr Julien Peltier
Professor Matthias Trost
Killing with proficiency: Integrated post-translational regulation of an offensive Type VI secretion system2018
Dr Julien Peltier
Professor Matthias Trost
LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages2018
Dr Julien Peltier
Professor Matthias Trost
Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase2018
Professor Matthias Trost
The MALDI-TOF E2/E3 Ligase Assay as Universal Tool for Drug Discovery in the Ubiquitin Pathway2018
Dr Katharina Trunk
Dr Julien Peltier
Professor Janet Quinn
Dr Henrik Strahl von Schulten
Professor Matthias Trost
et al.
The type VI secretion system deploys antifungal effectors against microbial competitors2018
Dr Julien Peltier
Professor Matthias Trost
Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib2018
Robert Gourlay
Professor Matthias Trost
A mutant O-GlcNAcase enriches Drosophila developmental regulators2017
Dr Julien Peltier
Dr Anetta Svitorka Hartlova
Professor Matthias Trost
Assessing the Phagosome Proteome by Quantitative Mass Spectrometry2017
Rachel Heap
Professor Matthias Trost
Identifying Inhibitors of Inflammation: A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs)2017
Dr Anetta Svitorka Hartlova
Dr Julien Peltier
Professor Matthias Trost
Isolation and Western Blotting of Latex-Bead Phagosomes to Track Phagosome Maturation2017
Professor Matthias Trost
Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a2017
Rachel Heap
Megan Gant
Frederic Lamoliatte
Dr Julien Peltier
Professor Matthias Trost
et al.
Mass spectrometry techniques for studying the ubiquitin system2017
Professor Matthias Trost
Patterns, Receptors, and Signals: Regulation of Phagosome Maturation2017
Professor Matthias Trost
USP7 small-molecule inhibitors interfere with ubiquitin binding2017
Professor Matthias Trost
Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation2016
Professor Matthias Trost
IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid2016
Professor Matthias Trost
mTORC1 and CK2 coordinate ternary and eIF4F complex assembly2016
Professor Matthias Trost
Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases2016
Dr Julien Peltier
Professor Matthias Trost
Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity2016
Dr Alexandra Solovyova
Professor Matthias Trost
UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome2016
Professor Matthias Trost
VgrG and PAAR proteins define distinct versions of a functional Type VI secretion system2016
Dr Julien Peltier
Professor Matthias Trost
Binding to serine 65‐phosphorylated ubiquitin primes Parkin for optimal PINK1‐dependent phosphorylation and activation2015
Professor Matthias Trost
High-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow-derived macrophages2015
Robert Gourlay
Professor Matthias Trost
Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK12015
Professor Matthias Trost
Quantitative proteome analysis of temporally-resolved phagosomes following uptake via key phagocytic receptors2015
Professor Matthias Trost
Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers2015
Professor Matthias Trost
A crucial role for β2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells2014
Professor Matthias Trost
Professor Tracy Palmer FRS FRSE FMedSci
Professor Frank Sargent
A holin and an endopeptidase are essential for chitinolytic protein secretion in Serratia marcescens2014
Robert Gourlay
Professor Matthias Trost
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Serine652014
Professor Matthias Trost
Protein kinase D2 is a digital amplifier of T cell receptor–stimulated diacylglycerol signaling in naïve CD8+ T cells2014
Professor Matthias Trost
Reproducible Automated Phosphopeptide Enrichment using Magnetic TiO2 and Ti-IMAC2014
Professor Matthias Trost
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry2014
Professor Matthias Trost
A combination of SILAC and nucleotide acyl phosphate labelling reveals unexpected targets of the Rsk inhibitor BI-D18702013