Toggle Main Menu Toggle Search

Open Access padlockePrints

An International Validation of the "DECAF Score" to Predict Disease Severity and Hospital Mortality in Acute Exacerbation of COPD in the UAE

Lookup NU author(s): Khadeija Almarshoodi, Dr Carlos EchevarriaORCiD, Professor Christopher WardORCiD

Downloads


Licence

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).


Abstract

© The Author(s) 2023.The DECAF score (the Dyspnea, Eosinopenia, Consolidation, Academia, and Atrial fibrillation score) has been adopted in some hospitals to predict the severity of Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD). However, DECAF score has not been widely evaluated or used in Middle Eastern countries. The present study aimed to validate the DECAF score for predicting in-hospital mortality in patients with AECOPD in the United Arab Emirates (UAE). This was a retrospective, observational study conducted in 19 hospitals in the UAE. Data were retrieved from the electronic records of patients admitted for AECOPD in 17 hospitals across the country. Patients aged more than 35 years who were diagnosed with AECOPD were included in the study. The validation of the DECAF Score for inpatient death, 30-days death, and 90-day readmission was conducted using the Area Under the Receiver Operator curve (AUROC). The AUROCDECAF curves for inpatient death, 30-days death, and 90-day readmission were 0.8 (95% CI: 0.8-0.9), 0.8 (95% CI: 0.7-0.8), and 0.8 (95% CI: 0.8-0.8), respectively. The model was a satisfactory fit to the data (Hosmer–Lemeshow statistic = 0.195, Nagelkerke R2 = 31.7%). There were significant differences in means of length of stay across patients with different DECAF score (P =.008). Patients with a DECAF score of 6 had the highest mean length of stay, which was 29.8 ± 31.4 days. Patients with a DECAF score of 0 had the lowest mean length of stay, which was 3.6 ± 2.0 days. The DECAF score is a strong predictive tool for inpatient death, 30 days mortality and 90-day readmission in UAE hospital settings. The DECAF score is an effective tool for predicating mortality and other disease outcomes in patients with AECOPD in the UAE; hence, clinicians would be more empowered to make appropriate clinical decisions by using the DECAF score.


Publication metadata

Author(s): Almarshoodi K, Echevarria C, Kassem A, Mahboub B, Salameh L, Ward C

Publication type: Article

Publication status: Published

Journal: Hospital Pharmacy

Year: 2024

Volume: 59

Issue: 2

Pages: 234-240

Print publication date: 01/04/2024

Online publication date: 03/11/2023

Acceptance date: 02/04/2023

Date deposited: 21/11/2023

ISSN (print): 0018-5787

ISSN (electronic): 1945-1253

Publisher: SAGE Publications Ltd

URL: https://doi.org/10.1177/00185787231209218

DOI: 10.1177/00185787231209218


Altmetrics

Altmetrics provided by Altmetric


Share