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Lookup NU author(s): Dr Meher Lad, Professor John-Paul TaylorORCiD, Professor Tim GriffithsORCiD
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© 2024 The AuthorsHearing loss is a risk-factor for dementia but the reasons for this are unclear. Subjective hearing loss is related to increased future dementia risk, however, this metric has not been previously examined with cognitive, neuroimaging and biochemical measures that are relevant to Alzheimer's disease. We assessed Cognitively Normal and Mild Cognitively Impaired participants from the Alzheimer's Disease Neuroimaging Initiative with subjective hearing loss to examine if they had faster decline in episodic memory scores, hippocampal volume and greater pTau positivity. The likelihood of a dementia diagnosis in hearing impaired participants over a 5-year period was also assessed. There were no statistically significant differences between the hearing subgroups over a 5-year period nor were there in conversions to a dementia diagnosis. Objective hearing loss metrics may provide a more reliable link between hearing loss and dementia risk.
Author(s): Lad M, Taylor J-P, Griffiths TD
Publication type: Article
Publication status: Published
Journal: Heliyon
Year: 2024
Volume: 10
Issue: 9
Online publication date: 03/05/2024
Acceptance date: 25/04/2024
Date deposited: 24/05/2024
ISSN (electronic): 2405-8440
Publisher: Elsevier
URL: https://doi.org/10.1016/j.heliyon.2024.e30423
DOI: 10.1016/j.heliyon.2024.e30423
Data Access Statement: Data from the manuscript was taken from the ADNI database and is available to registered and approved researchers.
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