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Subjective hearing loss is not associated with an increased risk of Alzheimer's disease dementia

Lookup NU author(s): Dr Meher Lad, Professor John-Paul TaylorORCiD, Professor Tim GriffithsORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Abstract

© 2024 The AuthorsHearing loss is a risk-factor for dementia but the reasons for this are unclear. Subjective hearing loss is related to increased future dementia risk, however, this metric has not been previously examined with cognitive, neuroimaging and biochemical measures that are relevant to Alzheimer's disease. We assessed Cognitively Normal and Mild Cognitively Impaired participants from the Alzheimer's Disease Neuroimaging Initiative with subjective hearing loss to examine if they had faster decline in episodic memory scores, hippocampal volume and greater pTau positivity. The likelihood of a dementia diagnosis in hearing impaired participants over a 5-year period was also assessed. There were no statistically significant differences between the hearing subgroups over a 5-year period nor were there in conversions to a dementia diagnosis. Objective hearing loss metrics may provide a more reliable link between hearing loss and dementia risk.

Publication metadata

Author(s): Lad M, Taylor J-P, Griffiths TD

Publication type: Article

Publication status: Published

Journal: Heliyon

Year: 2024

Volume: 10

Issue: 9

Online publication date: 03/05/2024

Acceptance date: 25/04/2024

Date deposited: 24/05/2024

ISSN (electronic): 2405-8440

Publisher: Elsevier

URL: https://doi.org/10.1016/j.heliyon.2024.e30423

DOI: 10.1016/j.heliyon.2024.e30423

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