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Prevention and Reduction of Anxiety in Autistic Preschoolers Through an Autism-Specific Parent-Mediated Intervention: A Pilot Randomised Controlled Trial Evaluating Short and Longer Term Outcomes

Lookup NU author(s): Emerita Professor Jacqueline Rodgers

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

© The Author(s) 2024. Anxiety is a common co-occurring condition for autistic preschoolers. Whilst there has been extensive research evaluating anxiety prevention/reduction interventions for neurotypical preschoolers, such research is limited for autistic children. Fifty-seven parents of autistic 4–5-year olds, with varying levels of anxiety, participated in a randomised controlled trial of an autism-specific, parent-mediated intervention (CLK-CUES) to prevent or reduce anxiety in autistic preschoolers. Baseline, short-term (post-intervention) and longer term (12 months follow-up) assessments included child anxiety (ASC-ASD-P and PAS-R), intolerance of uncertainty, and parent well-being. (Trial registration ACTRN12620001322921). There were no reports of harmful effects of the intervention or trial. Linear mixed models show a significant group x time interaction for ASC-ASD-P Total score and the Uncertainty subscale with medium and large effect sizes. Post-hoc analyses show a significant decline for only the intervention group in anxiety (specifically, anxiety around uncertainty) from pre-post intervention, maintained at one year follow-up. There was no change on the PAS-R or other ASC-ASD-P subscales. CLK-CUES shows promise as a way to prevent and reduce anxiety in young autistic children, specifically anxiety related to uncertainty. Trials with larger samples are warranted. Findings also highlight the importance of using measures designed for autistic children.


Publication metadata

Author(s): Adams D, Malone S, Dargue N, Keen D, Rodgers J, Simpson K, Wicks R, Bullot A, Rapee R

Publication type: Article

Publication status: Published

Journal: Journal of Autism and Developmental Disorders

Year: 2024

Pages: ePub ahead of print

Online publication date: 26/09/2024

Acceptance date: 16/09/2024

Date deposited: 23/10/2024

ISSN (print): 0162-3257

ISSN (electronic): 1573-3432

Publisher: Springer Nature

URL: https://doi.org/10.1007/s10803-024-06570-5

DOI: 10.1007/s10803-024-06570-5

PubMed id: 39325290


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Funding

Funder referenceFunder name
Australian Research Council (Grant No.: LP180100318)

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