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Systems analysis of miR-199a/b-5p and multiple miR-199a/b-5p targets during chondrogenesis

Lookup NU author(s): Dr Krutik Patel, Dr Matthew Barter, Dr Jamie Soul, Dr Peter Clark, Dr Carole Proctor, Dr Ian Clark, Professor David YoungORCiD, Dr Daryl Shanley

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Publication metadata

Author(s): Patel K, Barter M, Soul J, Clark P, Proctor C, Clark I, Young D, Shanley DP

Publication type: Article

Publication status: Published

Journal: eLife

Year: 2024

Volume: 12

Online publication date: 14/10/2024

Acceptance date: 17/07/2024

Date deposited: 24/10/2024

ISSN (electronic): 2050-084X

Publisher: eLife Sciences Publications Ltd.

URL: https://doi.org/10.7554/eLife.89701.4

DOI: 10.7554/eLife.89701

Data Access Statement: All scripts will be found in the following GitHub repository: https://github.com/Krutik6/MIR199ab5pChondrogenesis-Modelling-Paper/ (copy archived at Patel, 2024). The enhanced kinetic model can be found in the following biomodels repository MODEL2305010001. RNAseq data generated in this project can be found in GSE274379.

PubMed id: 39401064


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Funding

Funder referenceFunder name
Dunhill Medical Trust (R476/0516)
MRC and Versus Arthritis as part of the Medical Research Council Versus Arthritis Centre for Integrated Research into Musculoskeletal Ageing (CIMA) (MR/P020941/1 and MR/R502182/1)
Novo Nordisk Fonden Challenge Programme: Harnessing the Power of Big Data to Address the Societal Challenge of Aging (NNF17OC0027812)
Versus Arthritis (22043)

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