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Lookup NU author(s): Emeritus Professor Jan Scott
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© The Author(s) 2025. This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). People impacted by bipolar disorder are confronted by many unmet needs that contribute to the overall burden associated with the disorder. We do not have a good understanding of the underlying pathology of bipolar disorder, so we do not have biomarkers to accurately identify those who are at risk of developing the disorder. Delayed diagnosis is the norm, and it can take a decade or more for an individual to receive a diagnosis and to start appropriate treatment. We have evidence-based treatments such as lithium and psychosocial therapies; however, their availability and use are limited. We need a consolidated approach to advance indicated prevention and early intervention for bipolar disorder. In this viewpoint article, we describe these barriers in detail as well as introduce international and national work that is being done to progress the field. At the national level, we introduce the National Health and Medical Research Council Centre for Research Excellence in Bipolar Disorder. The Centre for Research Excellence in Bipolar Disorder comprises a multidisciplinary team of experts from Australia and internationally who are working together to develop a better understanding of opportunities for indicated prevention and early intervention as well as to improve interventions for those impacted by the disorder. Here we describe our research framework, stakeholder engagement activities and strategies for workforce development and capacity building. Ultimately by working together we will attempt to address many of issues faced by individuals impacted by bipolar disorder.
Author(s): Cotton SM, Hasty M, Mitchell P, Murray G, Hickie IB, McGorry PD, Walder K, Dean OM, Mihalopoulos C, Yung AR, Van Rheenen TE, Nierenberg AA, Scott J, Williams LJ, Berk L, Davey CG, Crouse JJ, Scott E, Iorfino F, Filia K, Chatterton ML, Macneil C, Perich T, Morton E, Ratheesh A, Berk M
Publication type: Article
Publication status: Published
Journal: Australian and New Zealand Journal of Psychiatry
Year: 2025
Pages: Epub ahead of print
Online publication date: 12/09/2025
Acceptance date: 02/04/2018
Date deposited: 07/10/2025
ISSN (print): 0004-8674
ISSN (electronic): 1440-1614
Publisher: SAGE Publications Inc.
URL: https://doi.org/10.1177/00048674251361727
DOI: 10.1177/00048674251361727
PubMed id: 40940688
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