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SPIRIT–Children and Adolescents (SPIRIT-C) 2026 Extension Statement: Enhancing the Reporting and Usefulness of Pediatric Randomized Trial Protocols

Lookup NU author(s): Professor Niina KolehmainenORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


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Author(s): Baba A, Smith M, Potter BK, Chan A, Moher D, Toulany A, Doherty-Kirby A, Nafria Escalera B, Stratton C, Gale C, Macarthur C, Purper-Ouakil D, Juszczak E, Cohen E, Reggiardo G, Preston J, Cohen JF, Upton J, Allegaert K, Boerner K, Mehta K, Nguyen KA, Courtney K, Hartling L, Konstantinidis M, Odermarsky M, Butcher NJ, Kolehmainen N, Longmuir PE, Gill PJ, Leroy P, Feneberg R, Poluru R, Morris S, Friedrichsdorf SJ, Nagy TJ, Klassen TP, Lacaze-Masmonteil T, Onland W, Offringa M

Publication type: Article

Publication status: Published

Journal: JAMA Pediatrics

Year: 2026

Pages: Epub ahead of print

Online publication date: 24/02/2026

Acceptance date: 15/01/2026

Date deposited: 05/12/2025

ISSN (print): 2168-6203

ISSN (electronic): 2168-6211

Publisher: American Medical Association

URL: https://doi.org/10.1001/jamapediatrics.2026.0113

DOI: 10.1001/jamapediatrics.2026.0113

ePrints DOI: 10.57711/vjdd-k588

Data Access Statement: All data supporting the findings of this study are available within the article and the online web appendices. Individual, anonymized responses from panelists or pilot testers are available from the corresponding author upon reasonable request.


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Funding

Funder referenceFunder name
CIHR Strategy for Patient-Oriented Research Innovative Clinical Trial multiyear grant from the CIHR (MYG 171 684)
Canadian Institutes of Health Research (CIHR) knowledge synthesis grant (KRS 329021)
Ontario Child Health Support Unit

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