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IL-18 Binding Protein, a biomarker of strength maintenance after surgery but reduced physical performance in age-related sarcopenia

Lookup NU author(s): Professor Miles WithamORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Publication metadata

Author(s): Paul R, Rossios C, Hinken AC, Neil D, Russell A, Witham MD, Griffiths MJ, Kemp PR

Publication type: Article

Publication status: Published

Journal: PLoS ONE

Year: 2026

Volume: 21

Issue: 1

Online publication date: 27/01/2026

Acceptance date: 22/12/2025

Date deposited: 08/01/2026

ISSN (electronic): 1932-6203

Publisher: Public Library of Science

URL: https://doi.org/10.1371/journal.pone.0340493

DOI: 10.1371/journal.pone.0340493


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Funding

Funder referenceFunder name
he Principal Investigator of the award was MW with PK, as a co applicant.
The SOMAscan analysis was funded by a GSK award (40453995) to PK with AR, AH and DN contributing to the design of this aspect of the work.
The LACE trial (proj ref 13/53/03) funded by Efficacy & Mechanism Evaluation (EME) Programme, an MRC & NIHR partnership funded CR.
The surgery cohort study was funded by the NIHR Respiratory Diseases Biomedical Research Unit at the Royal Brompton and Harefield NHS Trust (BRU 6279) which funded RP with MG and PK as applicants.

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