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Catabolism of serine enantiomers represses enterohemorrhagic Escherichia coli virulence factors via modulation of the nitrogen stress response

Lookup NU author(s): Dr James ConnollyORCiD

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Author(s): Addington E, Wale KR, Horsburgh E, Fargeas M, Spathis L, Lesniak W, Flavin S, Rimbi PT, Mark DR, Sandalli S, Serrano E, Blackburn G, Regnault C, Whitfield PD, Connolly JPR, Roe AJ, O'Boyle N

Publication type: Article

Publication status: Published

Journal: Proceedings of the National Academy of Sciences of the United States of America

Year: 2026

Volume: 123

Issue: 12

Print publication date: 24/03/2026

Online publication date: 18/03/2026

Acceptance date: 19/02/2026

Date deposited: 14/04/2026

ISSN (print): 0027-8424

ISSN (electronic): 1091-6490

Publisher: National Academy of Sciences

URL: https://doi.org/10.1073/pnas.2532916123

DOI: 10.1073/pnas.2532916123

Data Access Statement: RNA sequencing data have been deposited at The European Nucleotide Archive [PRJEB101298 (64) and PRJEB89299 (65)]. The empty pSS XylS/Pm vector sequence has been deposited at NCBI (PX119074) (66). Study data are included in the article and/or supporting information. https://www.pnas.org/lookup/doi/10.1073/pnas.2532916123#supplementary-materials

PubMed id: 41849392

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