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Browsing publications by Dr James Connolly.

Newcastle AuthorsTitleYearFull text
Dr James Connolly
Andrew Roe
A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens2024
Karla Helena Bueno
Chinenye Ekemezie
Charlotte Brown
Charlotte Dingwall
Dr Arnaud Basle
et al.
A new family of bacterial ribosome hibernation factors2024
Dr Curtis Cottam
Dr Lauren Beck
Professor Christopher Stewart
Dr Elisabeth Lowe
Dr James Connolly
et al.
Metabolism of l-arabinose converges with virulence regulation to promote enteric pathogen fitness2024
Andrew Roe
Dr James Connolly
Distinct ecological fitness factors coordinated by a conserved Escherichia coli regulator during systemic bloodstream infection2023
Elliot Macdonald
Dr James Connolly
Professor Henrik Strahl von Schulten
Dr Giusy Mariano
The novel anti-phage system Shield co-opts an RmuC domain to mediate phage defense across Pseudomonas species.2023
Elliot Macdonald
Dr James Connolly
Professor Henrik Strahl von Schulten
Professor Tracy Palmer FRS FRSE FMedSci
Dr Giusy Mariano
et al.
The novel anti-phage system Shield co-opts an RmuC domain to mediate phage defense across Pseudomonas species2023
Dr James Connolly
Control of resistance against bacteriophage killing by a metabolic regulator in meningitis-associated Escherichia coli2022
Dr James Connolly
d-Serine induces distinct transcriptomes in diverse Escherichia coli pathotypes2021
Dr James Connolly
Going virtual: A report from the sixth Young Microbiologists Symposium on ‘Microbe Signalling, Organisation and Pathogenesis’2021
Dr James Connolly
Prokaryotic life finds a way: insights from evolutionary experimentation in bacteria2021
Dr James Connolly
Genomic plasticity of pathogenic Escherichia coli mediates D-serine tolerance via multiple adaptive mechanisms2020
Dr James Connolly
Plastic Circuits: Regulatory Flexibility in Fine Tuning Pathogen Success2020
Dr James Connolly
Propionic Acid Promotes the Virulent Phenotype of Crohn’s Disease-Associated Adherent-Invasive Escherichia coli 2020
Dr James Connolly
Widespread strain-specific distinctions in chromosomal binding dynamics of a highly conserved Escherichia coli transcription factor2020
Dr James Connolly
Characterization of the mode of action of aurodox, a type III secretion system inhibitor from Streptomyces goldiniensis2019
Dr James Connolly
Distinct intraspecies virulence mechanisms regulated by a conserved transcription factor2019
Dr James Connolly
Genomic and transcriptomic characterization of Pseudomonas aeruginosa small colony variants derived from a chronic infection model2019
Dr James Connolly
Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis2018
Dr James Connolly
Author correction: Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion (Nature Communications, (2018), 9, 1, (4187), 10.1038/s41467-018-06701-4)2018
Dr James Connolly
Control freaks—signals and cues governing the regulation of virulence in attaching and effacing pathogens2018
Dr James Connolly
Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion2018
Dr James Connolly
Postgenomics characterization of an essential genetic determinant of mammary pathogenic Escherichia coli2018
Dr James Connolly
Tracking elusive cargo: Illuminating spatio-temporal Type 3 effector protein dynamics using reporters2018
Dr James Connolly
Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition2017
Dr James Connolly
A Highly Conserved Bacterial D-Serine Uptake System Links Host Metabolism and Virulence2016
Dr James Connolly
Identification and characterization of novel compounds blocking Shiga toxin expression in Escherichia coli O157:H72016
Dr James Connolly
Intracellular D-serine accumulation promotes genetic diversity via modulated induction of RecA in enterohemorrhagic Escherichia coli2016
Dr James Connolly
The highly conserved Escherichia coli transcription factor YhaJ regulates aromatic compound degradation2016
Dr James Connolly
When and where? Pathogenic Escherichia coli differentially sense host D-serine using a universal transporter system to monitor their environment2016
Dr James Connolly
Erratum: The host metabolite D-serine contributes to bacterial niche specificity through gene selection (ISME Journal (2015) 9 (1039-1051) DOI: 10.1038/ismej.2014.242)2015
Dr James Connolly
From ingestion to colonization: The influence of the host environment on regulation of the LEE encoded type III secretion system in enterohaemorrhagic Escherichia coli2015
Dr James Connolly
Professor Waldemar Vollmer
The host metabolite D-serine contributes to bacterial niche specificity through gene selection2015
Dr Kate Beckham
Dr James Connolly
The metabolic enzyme AdhE controls the virulence of Escherichia coli O157: H72014