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Browsing publications by
Dr James Connolly.
Newcastle Authors
Title
Year
Full text
Dr James Connolly
Andrew Roe
A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens
2024
Karla Helena Bueno
Chinenye Ekemezie
Charlotte Brown
Charlotte Dingwall
Dr Arnaud Basle
et al.
A new family of bacterial ribosome hibernation factors
2024
Dr Curtis Cottam
Dr Lauren Beck
Professor Christopher Stewart
Dr Elisabeth Lowe
Dr James Connolly
et al.
Metabolism of l-arabinose converges with virulence regulation to promote enteric pathogen fitness
2024
Andrew Roe
Dr James Connolly
Distinct ecological fitness factors coordinated by a conserved
Escherichia coli
regulator during systemic bloodstream infection
2023
Elliot Macdonald
Dr James Connolly
Professor Henrik Strahl von Schulten
Dr Giusy Mariano
The novel anti-phage system Shield co-opts an RmuC domain to mediate phage defense across
Pseudomonas
species.
2023
Elliot Macdonald
Dr James Connolly
Professor Henrik Strahl von Schulten
Professor Tracy Palmer FRS FRSE FMedSci
Dr Giusy Mariano
et al.
The novel anti-phage system Shield co-opts an RmuC domain to mediate phage defense across
Pseudomonas
species
2023
Dr James Connolly
Control of resistance against bacteriophage killing by a metabolic regulator in meningitis-associated
Escherichia coli
2022
Dr James Connolly
d-Serine induces distinct transcriptomes in diverse
Escherichia coli
pathotypes
2021
Dr James Connolly
Going virtual: A report from the sixth Young Microbiologists Symposium on ‘Microbe Signalling, Organisation and Pathogenesis’
2021
Dr James Connolly
Prokaryotic life finds a way: insights from evolutionary experimentation in bacteria
2021
Dr James Connolly
Genomic plasticity of pathogenic
Escherichia coli
mediates D-serine tolerance via multiple adaptive mechanisms
2020
Dr James Connolly
Plastic Circuits: Regulatory Flexibility in Fine Tuning Pathogen Success
2020
Dr James Connolly
Propionic Acid Promotes the Virulent Phenotype of Crohn’s Disease-Associated Adherent-Invasive
Escherichia coli
2020
Dr James Connolly
Widespread strain-specific distinctions in chromosomal binding dynamics of a highly conserved E
scherichia coli
transcription factor
2020
Dr James Connolly
Characterization of the mode of action of aurodox, a type III secretion system inhibitor from S
treptomyces goldiniensis
2019
Dr James Connolly
Distinct intraspecies virulence mechanisms regulated by a conserved transcription factor
2019
Dr James Connolly
Genomic and transcriptomic characterization of
Pseudomonas aeruginosa
small colony variants derived from a chronic infection model
2019
Dr James Connolly
Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis
2018
Dr James Connolly
Author correction: Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion (
Nature Communications
, (2018), 9, 1, (4187), 10.1038/s41467-018-06701-4)
2018
Dr James Connolly
Control freaks—signals and cues governing the regulation of virulence in attaching and effacing pathogens
2018
Dr James Connolly
Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion
2018
Dr James Connolly
Postgenomics characterization of an essential genetic determinant of mammary pathogenic
Escherichia coli
2018
Dr James Connolly
Tracking elusive cargo: Illuminating spatio-temporal Type 3 effector protein dynamics using reporters
2018
Dr James Connolly
Novel compounds targeting the enterohemorrhagic
Escherichia coli
type three secretion system reveal insights into mechanisms of secretion inhibition
2017
Dr James Connolly
A Highly Conserved Bacterial D-Serine Uptake System Links Host Metabolism and Virulence
2016
Dr James Connolly
Identification and characterization of novel compounds blocking Shiga toxin expression in
Escherichia coli
O157:H7
2016
Dr James Connolly
Intracellular D-serine accumulation promotes genetic diversity via modulated induction of RecA in enterohemorrhagic
Escherichia coli
2016
Dr James Connolly
The highly conserved
Escherichia coli
transcription factor YhaJ regulates aromatic compound degradation
2016
Dr James Connolly
When and where? Pathogenic
Escherichia coli
differentially sense host D-serine using a universal transporter system to monitor their environment
2016
Dr James Connolly
Erratum: The host metabolite D-serine contributes to bacterial niche specificity through gene selection (
ISME Journal
(2015) 9 (1039-1051) DOI: 10.1038/ismej.2014.242)
2015
Dr James Connolly
From ingestion to colonization: The influence of the host environment on regulation of the LEE encoded type III secretion system in enterohaemorrhagic
Escherichia coli
2015
Dr James Connolly
Professor Waldemar Vollmer
The host metabolite D-serine contributes to bacterial niche specificity through gene selection
2015
Dr Kate Beckham
Dr James Connolly
The metabolic enzyme AdhE controls the virulence of
Escherichia coli
O157: H7
2014