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HLA-DRB1*01:03 in patients with inflammatory bowel disease: a genotype-phenotype association study

Lookup NU author(s): Dr Nicola WyattORCiD, Dr Robert Lees, Dr Robert MulliganORCiD, Professor Chris LambORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


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Author(s): Zhang Q, Shakweh E, Sharip MT, Zare B, Roberts C, Wyatt NJ, Clough J, Bewshea C, Garwany OE, Lees R, Mukhtar S, Rehman H, Thistle H, Mulligan R, Taylor M, Raymode P, Hamilton B, Noor NM, Morda F, Taylor M, Gyanwali M, Tobi O, Kateroglou S, Von Hagt S, Sebastian S, Hart A, Keylock L, Pele L, Lees CW, Raine T, Lamb CA, Anderson CA, Ahmad T, Uhlig H, Parkes M, Fachal L, Kennedy NA, Lee JC

Publication type: Article

Publication status: Published

Journal: Lancet Gastroenterology and Hepatology

Year: 2026

Pages: Epub ahead of print

Online publication date: 15/06/2026

Acceptance date: 02/04/2018

Date deposited: 03/07/2026

ISSN (print): 2468-1253

ISSN (electronic): 2468-1156

Publisher: The Lancet Publishing Group

URL: https://doi.org/10.1016/S2468-1253(26)00113-5

DOI: 10.1016/S2468-1253(26)00113-5

Data Access Statement: Genotype data from UKIBDGC have been deposited in the European Genome-phenome Archive (https://ega-archive.org), which is hosted by the European Bioinformatics Institute and the Centre for Genomic Regulation, and are available under accessions EGAD00000000005, EGAS00000000084, and EGAS00001000924.


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Funding

Funder referenceFunder name
AstraZeneca's Centre for Genomics Research who funded the clinical data refresh.
NIHR, the Medical Research Council, Open Targets, Crohn's & Colitis UK, the Helmsley Charitable Trust, Crohn's in Childhood Research Association,
Wellcome Trust (grant numbers 206194 and 220540/Z/20/A)

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