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Lookup NU author(s): Dr Ian Cowell
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The human glutathione S-transferase pi gene has been isolated from a cosmid library. The gene spans approximately 3 kb, is interrupted by six introns and the region around its 5' end has the high G + C and CpG content typical of an HTF (HpaII tiny fragment) island. In addition to a TATA box at position -28 relative to the transcription initiation site and two G + C boxes (GGGCGG), the promoter contains a sequence motif matching the phorbol ester- and ras-responsive element from the polyoma virus enhancer
Author(s): Cowell IG, Dixon KH, Pemble SE, Ketterer B, Taylor JB
Publication type: Article
Publication status: Published
Journal: Biochemical Journal
Print publication date: 01/10/1988
ISSN (print): 0264-6021
ISSN (electronic): 1470-8728
Publisher: Portland Press Ltd.
PubMed id: 3196325