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Browsing publications by Dr Ian Cowell

Newcastle AuthorsTitleYearFull text
Dr Ian Cowell
Emerita Professor Caroline Austin
Myeloperoxidase inhibition protects bone marrow mononuclear cells from DNA damage induced by the TOP2 poison anti-cancer drug etoposide2024
Dr Ian Cowell
Emerita Professor Caroline Austin
DNA fragility at the KMT2A/MLL locus: insights from old and new technologies2023
Dr Ian Cowell
John Casement
Emerita Professor Caroline Austin
To Break or Not to Break: The Role of TOP2B in Transcription2023
Elise Ling
Dr Arnaud Basle
Dr Ian Cowell
Professor Bert van den Berg
Emerita Professor Caroline Austin
A comprehensive structural analysis of the ATPase domain of Human DNA topoisomerase II Beta bound to AMPPNP, ADP and the bisdioxopiperazine, ICRF1932022
Dr Ian Cowell
Emerita Professor Caroline Austin
Disease-associated Mutations in Topoisomerase IIβ Result in Defective NK cells2022
Rebecca Swan
Dr Ian Cowell
Emerita Professor Caroline Austin
Mechanisms to Repair Stalled Topoisomerase II-DNA Covalent Complexes2022
Mushtaq Khazeem
John Casement
Dr Niall Kenneth
Jade McGow
Dr Ian Cowell
et al.		TOP2B Is Required to Maintain the Adrenergic Neural Phenotype and for ATRA‑Induced Differentiation of SH‑SY5Y Neuroblastoma Cells2022
Dr Katja Menger
Dr James Chapman
Mushtaq Khazeem
Dr Dasha Deen
John Casement
et al.		Two type I topoisomerases maintain DNA topology in human mitochondria2022
Rebecca Swan
Dr Ian Cowell
Emerita Professor Caroline Austin
A role for VCP/p97 in the processing of drug-stabilized TOP2-DNA covalent complexes2021
Emerita Professor Caroline Austin
Dr Ian Cowell
Mushtaq Khazeem
Dawn Lok
Huei Teng Ng
TOP2B’s contributions to transcription2021
Rebecca Swan
Luke Poh
Dr Ian Cowell
Emerita Professor Caroline Austin
Small molecule inhibitors confirm ubiquitin-dependent removal of TOP2-DNA covalent complexes2020
Mushtaq Khazeem
Dr Ian Cowell
Lauren Harkin
John Casement
Emerita Professor Caroline Austin
Transcription of carbonyl reductase 1 is regulated by DNA topoisomerase II beta2020
Dr Mandeep Atwal
Rebecca Swan
Ka Lee
Dr David Lee
Professor Lyle Armstrong
et al.		Intercalating TOP2 poisons attenuate topoisomerase action at higher concentrations2019
Dr Ian Cowell
Emerita Professor Caroline Austin
Mutations in topoisomerase IIβ result in a B cell immunodeficiency2019
Dr Ian Cowell
Elise Ling
Becky Swan
Emerita Professor Caroline Austin
The Deubiquitinating Enzyme Inhibitor PR-619 is a Potent DNA Topoisomerase II Poison s2019
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