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Repression versus activation in the control of gene transcription

Lookup NU author(s): Dr Ian Cowell

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Abstract

Studies on the regulation of transcription often focus on mechanisms of transcriptional activation. However, transcriptional repression is also an important factor in the regulation of many genes. Transcription of specific genes can be downregulated in various ways, and examination of a number of different systems has revealed that most or all steps required for transcriptional activation can be interfered with by transcriptional repressors


Publication metadata

Author(s): Cowell IG

Publication type: Review

Publication status: Published

Journal: Trends in Biochemical Sciences

Year: 1994

Volume: 19

Issue: 1

Pages: 38-42

Print publication date: 01/01/1994

ISSN (print): 0968-0004

ISSN (electronic): 0167-7640

URL: http://dx.doi.org/10.1016/0968-0004(94)90172-4

DOI: 10.1016/0968-0004(94)90172-4

PubMed id: 8140620


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