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Lookup NU author(s): Dr Janet Lindsey
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Telomeric DNA in the skin cells of 21 human subjects aged between 0 and 92 years was quantified by determining the length of the telomeric smear and the relative amount of TTAGGG repeat sequences. Both telomere length and quantity of telomeric repeat sequences were found to decrease significantly with age. Telomere loss has previously been postulated to be a caused of cell senescence.
Author(s): Lindsey JC, McGill NI, Lindsey LA, Green DK, Cooke HJ
Publication type: Article
Publication status: Published
Journal: Mutation Research - DNAging
Print publication date: 01/01/1991
ISSN (print): 0921-8734
ISSN (electronic): 1568-7864
Publisher: Elsevier B.V.
PubMed id: PMID: 1944
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