Toggle Main Menu Toggle Search

Open Access padlockePrints

Browsing publications by Dr Janet Lindsey.

Newcastle AuthorsTitleYearFull text
Dr Stephen Crosier
Dr Debbie Hicks
Dr Ed Schwalbe
Dr Daniel Williamson
Amanda Smith
et al.
Advanced molecular pathology for rare tumours: A national feasibility study and model for centralised medulloblastoma diagnostics2021
Dr Debbie Hicks
Dr Reza Rafiee
Dr Ed Schwalbe
Dr Christopher Howell
Dr Janet Lindsey
et al.
The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second-generation subtypes2021
Dr Yura Grabovska
Dr Stephen Crosier
Dr Martina Finetti
Dr Ed Schwalbe
Dr Rebecca Hill
et al.
Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity2020
Dr Rebecca Hill
Dr Stacey Richardson
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Janet Lindsey
et al.
Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study2020
Dr Ed Schwalbe
Dr Daniel Williamson
Dr Janet Lindsey
Dr Rebecca Hill
Dr Debbie Hicks
et al.
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes2019
Professor Steven Clifford
Dr Debbie Hicks
Dr Janet Lindsey
Dr Rebecca Hill
Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours2017
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures2017
Dr Ed Schwalbe
Dr Janet Lindsey
Dr Sirintra Nakjang
Dr Stephen Crosier
Amanda Smith
et al.
Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study2017
Professor Simon Bailey
Dr Janet Lindsey
Professor Steven Clifford
Divergent clonal selection dominates medulloblastoma at recurrence2016
Dr Janet Lindsey
Dr Rebecca Hill
Dr Ed Schwalbe
Dr Christopher Howell
Dr Reza Rafiee
et al.
Molecular and Prognostic Heterogeneity within MYC and MYCN Amplified Medulloblastomas2016
Dr Debbie Hicks
Dr Reza Rafiee
Dr Ed Schwalbe
Dr Christopher Howell
Dr Janet Lindsey
et al.
Subgroup-Directed Stratification of Risk in Infant Medulloblastoma2016
Dr Daniel Williamson
Dr Janet Lindsey
Dr Debbie Hicks
Dr Stephen Crosier
Amanda Smith
et al.
The Transcriptional Landscape of Medulloblastoma: Group 3 and Group 4 Tumours Comprise a Single Clinically Significant Expression Continuum2016
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Karen Barker
Dr Daniel Williamson
et al.
Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease2015
Dr Janet Lindsey
Dr Ed Schwalbe
Matthew Selby
Dr James Hayden
Dr Daniel Williamson
et al.
Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance2015
Dr Janet Lindsey
Dr Ed Schwalbe
Sandeep Potluri
Professor Simon Bailey
Dr Daniel Williamson
et al.
TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours2014
Dr Janet Lindsey
Dr Ed Schwalbe
Dr James Hayden
Professor David Ellison
Dr Daniel Williamson
et al.
Cross-Species Epigenetics Identifies a Critial Role for VAV1 in the Maintenance of Sonic Hedgehog Subgroup Medulloblastomas2014
Professor Simon Bailey
Dr Janet Lindsey
Professor Steven Clifford
Cytogenetic Prognostication Within Medulloblastoma Subgroups2014
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Daniel Williamson
Dr Sarra Ryan
et al.
MYC and TP53 defects emerge and interact at medulloblastoma relapse, define rapidly progressive disease and can be targeted therapeutically2014
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Karen Barker
Dr Daniel Williamson
et al.
MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically2014
Dr Ed Schwalbe
Dr Daniel Williamson
Dr Janet Lindsey
Dolores Hamilton
Sarra Ryan
et al.
DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies2013
Dr Ed Schwalbe
Dr James Hayden
Dr Janet Lindsey
Dr Rebecca Hill
Sarah Nicholson
et al.
Histologically defined central nervous system primitive neuro-ectodermal tumours (CNS-PNETs) display heterogeneous DNA methylation profiles and show relationships to other paediatric brain tumour types2013
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Professor Simon Bailey
Professor Steven Clifford
et al.
Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma2013
Dr Ed Schwalbe
Dr Janet Lindsey
Dr Daniel Williamson
Kieran O'Toole
Dr Meryl Lusher
et al.
Epigenetic sub-classification and risk-stratification of medulloblastoma using DNA methylomics2012
Dr Janet Lindsey
Professor Simon Bailey
Professor Steven Clifford
Subgroup-specific structural variation across 1,000 medulloblastoma genomes2012
Dr Ed Schwalbe
Dr Janet Lindsey
Debbie Straughton
Mike Cole
Dr Hisham Megahed
et al.
Rapid Diagnosis of Medulloblastoma Molecular Subgroups2011
Dr Meryl Lusher
Dr Janet Lindsey
Professor Steven Clifford
RASSF1A and the BH3-only mimetic ABT-737 promote apoptosis in pediatric medulloblastoma cell lines2011
Dr Janet Lindsey
Dr Rebecca Hill
Dr Hisham Megahed
Dr Meryl Lusher
Dr Ed Schwalbe
et al.
TP53 Mutations in Favorable-Risk Wnt/Wingless-Subtype Medulloblastomas2011
Dr Ed Schwalbe
Dr Janet Lindsey
Dr Meryl Lusher
Kieran O'Toole
Sarah Nicholson
et al.
DNA methylomics identifies clinically significant epigenetic subgroups of medulloblastoma2010
Dr James Hayden
Dr Matthew Allen
Dr Sarra Ryan
Sarah Nicholson
Dr Ed Schwalbe
et al.
Molecular Mechanisms in Supratentorial CNS-PNET development2010
Dr Janet Lindsey
Professor Steven Clifford
Professor David Ellison
Dr Richard Gilbertson
Subtypes of medulloblastoma have distinct developmental origins2010
Dr Janet Lindsey
Professor Steven Clifford
Methylation-Controlled J Protein2009
Jennifer Anderton
Dr Janet Lindsey
Dr Meryl Lusher
Dr Richard Gilbertson
Professor Simon Bailey
et al.
Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A22008
Professor Steven Clifford
Dr Meryl Lusher
Dr Janet Lindsey
Dr Jackie Langdon
Dr Richard Gilbertson
et al.
Wnt-pathway medulloblastomas2008
Professor David Ellison
Dr Janet Lindsey
Dr Meryl Lusher
Professor Steven Clifford
Beta-catenin status predicts favorable prognosis in childhood medulloblastoma2007
Dr Janet Lindsey
Dr Meryl Lusher
Jennifer Anderton
Dr Richard Gilbertson
Professor David Ellison
et al.
Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma2007
Olabisi Onilude
Dr Meryl Lusher
Dr Janet Lindsey
Professor Andrew Pearson
Professor David Ellison
et al.
APC and CTNNB1 mutations are rare in sporadic ependymomas2006
Dr Janet Lindsey
Dr Meryl Lusher
Dr Gordon Strathdee
Robert Brown
Dr Richard Gilbertson
et al.
Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours2006
Dr Janet Lindsey
Dr Meryl Lusher
Dr Gordon Strathdee
Dr Richard Gilbertson
Professor Simon Bailey
et al.
Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours2006
Professor Steven Clifford
Dr Meryl Lusher
Dr Janet Lindsey
Dr Jackie Langdon
Dr Richard Gilbertson
et al.
Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis2006
Professor David Ellison
Olabisi Onilude
Dr Janet Lindsey
Dr Meryl Lusher
Professor Andrew Pearson
et al.
β-catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour Committee2005
Dr Janet Lindsey
Jennifer Anderton
Dr Meryl Lusher
Professor Steven Clifford
Epigenetic events in medulloblastoma development2005
David Hamilton
Dr Meryl Lusher
Dr Janet Lindsey
Professor David Ellison
Professor Steven Clifford
et al.
Epigenetic inactivation of the RASSF1A tumour suppressor gene in ependymoma2005
Professor Steven Clifford
Dr Janet Lindsey
Dr Meryl Lusher
Dr Richard Gilbertson
Professor Andrew Pearson
et al.
Identification of tumour suppressor genes in childhood medulloblastoma by promoter hypermethylation profiling2004
Dr Janet Lindsey
Dr Meryl Lusher
Jennifer Anderton
Professor Simon Bailey
Dr Richard Gilbertson
et al.
Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling2004
Dr Adrian Frank
Roberto Hernan
Dr Janet Lindsey
Dr Meryl Lusher
Professor Steven Clifford
et al.
The TP53-ARF tumor suppressor pathway is frequently disrupted in large/cell anaplastic medulloblastoma2004
Dr Janet Lindsey
Dr Meryl Lusher
Professor Mark Birch-Machin
Current pitfalls in the measurement of the 4977 bp mitochondrial DNA common deletion in human skin2003
Dr Janet Lindsey
Dr Meryl Lusher
Professor Andrew Pearson
Professor David Ellison
Professor Steven Clifford
et al.
Identification of tumour suppressor genes in childhood medulloblastoma by promoter hypermethylation profiling2003
Dr Debbie Scott
Dr Janet Lindsey
Dr Meryl Lusher
Professor Andrew Pearson
Professor David Ellison
et al.
Identification of tumour suppressor loci on chromosome 10q in medulloblastoma2003
Dr Meryl Lusher
Dr Janet Lindsey
Professor Andrew Pearson
Professor David Ellison
Professor Steven Clifford
et al.
Biallelic epigenetic inactivation of the RASSF1A tumor suppressor gene in medulloblastoma development2002
Dr Janet Lindsey
Dr Meryl Lusher
Emerita Professor Katherine Bushby
Professor Pamela Shaw
Genotype-phenotype correlation in hereditary spastic paraparesis2001
Dr Meryl Lusher
Dr Janet Lindsey
Emeritus Professor Doug Turnbull
Emerita Professor Katherine Bushby
Professor Pamela Shaw
et al.
Paraplegin gene analysis in hereditary spastic paraparesis (HSP) pedigrees in northeast England.2001
Dr Kathleen White
Dr Meryl Lusher
Dr Janet Lindsey
Professor Pamela Shaw
Emerita Professor Katherine Bushby
et al.
Clinical and pathologic findings in hereditary spastic paraparesis with spastin mutation2000
Dr Janet Lindsey
Dr Meryl Lusher
Dr Kathleen White
Dr Rumaisa Bashir
Professor Pamela Shaw
et al.
Mutation analysis of the spastin gene (SPG4) in patients with hereditary spastic paraparesis2000
Dr Janet Lindsey
Replication strand preference for deletions associated with DNA palindromes1998
Simon Carter
Dr Janet Lindsey
Dr Rumaisa Bashir
A new locus for autosomal dominant retinitis pigmentosa on chromosome 7p1993
Dr Janet Lindsey
Dr Surinder Papiha
Exclusion of chromosome 6 and 8 locations in nonrhodopsin autosomal dominant retinitis pigmentosa families: further locus heterogeneity in adRP1992
Dr Janet Lindsey
Recombination between rhodopsin and locus D3S47 (C17) in rhodopsin retinitis pigmentosa families1992
Dr Janet Lindsey
In vivo loss of telomeric repeats with age in humans1991
Dr Janet Lindsey
The structure of a subterminal repeated sequence present on many human chromosomes1990
Dr Janet Lindsey
Slow replication of palindrome-containing DNA1989
Dr Janet Lindsey
Genome interactions which influence DNA palindrome mediated instability and inviability in Escherichia coli1987
Dr Janet Lindsey
In vivo loss of supercoiled DNA carrying a palindromic sequence1986