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Lookup NU author(s): Dr Geoffrey Coxon,
Professor Del Besra,
Professor David Minnikin
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(11R, 12S)-Lactobacillic acid (1) has been prepared either from D- mannitol by asymmetric cyclopropanation or from cis-cyclopropane-1, 2- dimethanol by enzymatic desymmetrisation. The syntheses of (l1S 12R)- lactobacillic acid (2) and (1R, 2S) 1- (3'-methoxycarbonylpropyl)-2- octadecylcyclopropane (26) and related analogues (27 and 28) have also been achieved.
Author(s): Coxon GD, Knobl S, Roberts E, Baird MS, Al Dulayymi JR, Besra GS, Brennan PJ, Minnikin DE
Publication type: Article
Publication status: Published
Journal: Tetrahedron Letters
Print publication date: 03/09/1999
ISSN (print): 0040-4039
ISSN (electronic): 1873-3581
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