Publications by Professor Del Besra - ePrints

Browsing publications by Professor Del Besra.

Newcastle Authors	Title	Year
Dr Laurent Kremer Kevin Gibson Professor David Minnikin Professor Del Besra	Identification and structural characterization of an unusual mycobacterial monomeromycolyl-diacylglycerol	2005
Suzanne Senior Dr Petr Illarionov Dr Sudagar Gurcha Professor David Minnikin Professor Del Besra et al.	Acetylene-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme	2004
Dr Geoffrey Coxon Professor Del Besra Professor David Minnikin	Synthesis and properties of methyl 5-(1′R,2′S)-(2- octadecylcycloprop-1-yl)pentanoate and other ω-19 chiral cyclopropane fatty acids and esters related to mycobacterial mycolic acids	2004
Professor David Minnikin Professor Del Besra	A type II pathway for fatty acid biosynthesis presents drug targets in Plasmodium falciparum	2003
Professor Del Besra	Activation of V alpha 14i NKT cells requires a unique kinetics for the TCR interaction	2003
Suzanne Senior Dr Petr Illarionov Dr Sudagar Gurcha Professor David Minnikin Professor Del Besra et al.	Biphenyl-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme	2003
Kevin Gibson Dr Jerome Nigou Professor Del Besra	Identification of a novel mannose-capped lipoarabinomannan from Amycolatopsis sulphurea	2003
Kevin Gibson Dr Jerome Nigou Professor Del Besra	Structural and functional features of Rhodococcus ruber lipoarabinomannan	2003
Suzanne Senior Professor Del Besra Professor David Minnikin	Analogues of thiolactomycin: potential drugs with enhanced anti-mycobacterial activity	2002
Professor Del Besra	Characterization and regulation of inositol monophosphatase activity in Mycobacterium smegmatis	2002
Dr Laurent Kremer Dr Sudagar Gurcha Professor Del Besra	Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis	2002
Dr Sudagar Gurcha Dr Jerome Nigou Professor Del Besra	Characterization of mycobacterial protein glycosyltransferase activity using synthetic peptide acceptors in a cell-free assay	2002
Dr Jerome Nigou Professor Del Besra	Cytidine diphosphate-diacylglycerol synthesis in Mycobacterium smegmatis	2002
Dr Sudagar Gurcha Professor Del Besra	Disaccharides as photoaffinity probes for arabinosyl and galactosyl transferase activities in Mycobacterium tuberculosis	2002
Professor Del Besra	Fine specificity of TCR complementarity-determining region residues and lipid antigen hydrophilic moieties in the recognition of a CD1-lipid complex	2002
Professor Del Besra	Ligation of arabinogalactan to peptidoglycan in the cell wall of Mycobacterium smegmatis requires concomitant synthesis of the two wall polymers	2002
Mark Guy Professor Del Besra	Lipid length controls antigen entry into endosomal and nonendosomal pathways for CDIb presentation	2002
Dr Laurent Kremer Dr Lynn Dover Dr Severine Carrere Dr Madhavan Nampoothiri Dr Alistair Brown et al.	Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis	2002
Dr Sudagar Gurcha Dr Laurent Kremer Professor Del Besra	Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis	2002
Dr Jerome Nigou Dr Lynn Dover Professor Del Besra	Purification and biochemical characterization of Mycobacterium tuberculosis suhB, an inositol monophosphatase involved in inositol biosynthesis	2002
Dr Laurent Kremer Professor Del Besra	Re-emergence of tuberculosis: strategies and treatment	2002
Dr Sudagar Gurcha Professor Del Besra	Studies on n-octyl-5-(alpha-D-arabinofuranosyl)-beta-D-galactofuranosides for mycobacterial glycosyltransferase activity	2002
Dr Sudagar Gurcha Professor Del Besra	Synthesis of an arabinofuranosyl disaccharide photoaffinity probe for arabinosyltransferase activity in Mycobacterium tuberculosis	2002
Dr Sudagar Gurcha Professor Del Besra	The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis	2002
Dr Laurent Kremer Dr William Maughan Rosalind Wilson Dr Lynn Dover Professor Del Besra et al.	The M-tuberculosis antigen 85 complex and mycolyltransferase activity	2002
Dr Laurent Kremer Dr Madhavan Nampoothiri Dr Lynn Dover Professor David Minnikin Professor Del Besra et al.	Biochemical Characterization of Acyl Carrier Protein (AcpM) and Malonyl-CoA:AcpM Transacylase (mtFabD), Two Major Components of Mycobacterium tuberculosis Fatty Acid Synthase II	2001
Dr Laurent Kremer Dr Lynn Dover Professor Del Besra	Galactan biosynthesis in Mycobacterium tuberculosis: Identification of a bifunctional UDP-galactofuranosyltransferase	2001
Professor Del Besra	Glycolipid targets of CD1-mediated T-cell responses	2001
Dr Sudagar Gurcha Professor Del Besra	Studies on (beta,1 -> 5) and (beta,1 -> 6) linked octyl Gal(f) disaccharides as substrates for mycobacterial galactosyltransferase activity	2001
Dr Sudagar Gurcha Professor Del Besra	Studies on alpha(1 -> 5) linked octyl arabinofuranosyl disaccharides for mycobacterial arabinosyl transferase activity	2001
Mark Guy Professor Del Besra	Synthetic mannosides act as acceptors for mycobacterial α1-6 mannosyltransferase	2001
Joanne Betts Professor Del Besra	Activation of the pro-drug ethionamide is regulated in mycobacteria	2000
Professor Del Besra	Biosynthesis of the galactan component of the mycobacterial cell wall	2000
Mark Guy Professor Del Besra	Cd1b-mediated T cell recognition of a glycolipid antigen generated from mycobacterial lipid and host carbohydrate during infection	2000
Dr Sudagar Gurcha Professor Del Besra	CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection	2000
Professor Del Besra	Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines	2000
Dr Laurent Kremer Professor Del Besra	Identification and substrate specificity of β-Ketoacyl (Acyl carrier protein) synthase III (mtFabH) from mycobacterium tuberculosis	2000
Professor Del Besra	Polyprenyl phosphate biosynthesis in Mycobacterium tuberculosis and Myobacterium smegmatis	2000
Professor David Minnikin Professor Del Besra	Antimycobacterial activities of isoxyl and new derivatives through the inhibition of mycolic acid synthesis	1999
Professor Del Besra	CD1c mediates B cell presentation of self and foreign isoprenoid glycolipids to T cells	1999
Dr Laurent Kremer Professor Del Besra	Lipoarabinomannan: Structure and functions of a glycolipid involved in tuberculosis pathogenicity	1999
Professor Del Besra	Phosphatidylinositol synthesis in mycobacteria	1999
Professor Del Besra	Studies on β-D-Gal(f)-(1→4)-α-L-Rha(p) octyl analogues as substrates for mycobacterial galactosyl transferase activity	1999
Professor Del Besra	The molecular basis of CD1-mediated presentation of lipid antigens	1999
Professor Del Besra	The pimB gene of Mycobacterium tuberculosis encodes a mannosyltransferase involved in lipoarabinomannan biosynthesis	1999
Dr Geoffrey Coxon Professor Del Besra Professor David Minnikin	The synthesis of both enantiomers of lactobacillic acid and mycolic acid analogues	1999
Professor Del Besra	Uptake and processing of glycosylated mycolates for presentation to CD1b-restricted T cells	1999