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Towards an e-biology of ageing: Integrating theory and data

Lookup NU author(s): Emeritus Professor Thomas Kirkwood, Professor Richard Boys, Dr Colin GillespieORCiD, Dr Carole Proctor, Dr Daryl Shanley, Professor Darren Wilkinson


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Ageing is a highly complex process; it involves interactions between numerous biochemical and cellular mechanisms that affect many tissues in an organism. Although work on the biology of ageing is now advancing quickly, this inherent complexity means that information remains highly fragmented. We describe how a new web-based modelling initiative is seeking to integrate data and hypotheses from diverse biological sources.

Publication metadata

Author(s): Kirkwood TBL, Boys RJ, Gillespie CJ, Proctor CJ, Shanley DP, Wilkinson DJ

Publication type: Review

Publication status: Published

Journal: Nature Reviews Molecular Cell Biology

Year: 2003

Volume: 4

Issue: 3

Pages: 243-249

Print publication date: 01/03/2003

ISSN (print): 1471-0072

ISSN (electronic): 1471-0080


DOI: 10.1038/nrm1051

PubMed id: 12612643