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A randomized controlled trial of implant-retained mandibular overdentures

Lookup NU author(s): Patrick Allen, Professor Mark Thomason, Dr Nick Jepson, Francis Nohl, Professor Janice EllisORCiD


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Evidence from randomized clinical trials of implant-retained overdentures is very limited at the present time. The aim of this study was to compare implant-retained mandibular overdentures and conventional complete dentures in a randomized controlled trial (RCT). Our a priori hypothesis was that implant-retained mandibular overdentures would be significantly better than conventional complete dentures. Edentulous patients (n = 118) were randomly allocated to either an Implant Group (n = 62) or a Denture Group (n = 56). Patients completed the Oral Health Impact Profile (OHIP) and a denture satisfaction scale pre-treatment and three months post-treatment. Upon completion of treatment, both groups reported improvement (p < 0.001, Wilcoxon Ranks Sum test) in oral-health-related quality of life and denture satisfaction. There were no significant post-treatment differences between the groups, but a treatment effect may be masked by application of "intention to treat" analysis. The OHIP change scores were significantly greater for patients receiving implants than for those who refused them.

Publication metadata

Author(s): Allen PF, Thomason JM, Jepson NJA, Nohl F, Smith DG, Ellis J

Publication type: Article

Publication status: Published

Journal: Journal of Dental Research

Year: 2006

Volume: 85

Issue: 6

Pages: 547-551

ISSN (print): 0022-0345

ISSN (electronic): 1544-0591

Publisher: Sage


DOI: 10.1177/154405910608500613

PubMed id: 16723653


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