ePrints

The Genetics of Cancer Survivorship

Lookup NU author(s): Professor James Allan

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.

Abstract

Constitutional (hereditary) genetic variation and somatic genetic alterations acquired during transformation to the neoplastic phenotype are both critical determinants of cancer outcome, and can ultimately have a significant effect on cancer survivorship. This article discusses the role of constitutional and somatic genetics in determining outcome and survivorship following a diagnosis of cancer using illustrative examples primarily from the hematologic malignancies. © 2008 Elsevier Inc. All rights reserved.

Publication metadata

Author(s): Allan JM

Publication type: Review

Publication status: Published

Journal: Hematology/Oncology Clinics of North America

Year: 2008

Volume: 22

Issue: 2

Pages: 257-269

ISSN (print): 0889-8588

ISSN (electronic): 1558-1977

URL: http://dx.doi.org/10.1016/j.hoc.2008.01.001

DOI: 10.1016/j.hoc.2008.01.001

PubMed id: 18395149

Share