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Browsing publications by Professor James Allan.

Newcastle AuthorsTitleYearFull text
Dr Wei-yu Lin
Dr Sarah Fordham
Dr Nicola Sunter
Dr Claire Elstob
Dr Yaobo Xu
et al.
Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia (Nature Communications, (2021), 12, 1, (6233), 10.1038/s41467-021-26551-x)2022
Professor James Allan
Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility2021
Dr Wei-Yu Lin
Dr Sarah Fordham
Dr Nicola Sunter
Dr Claire Elstob
Dr Thahira Rahman
et al.
Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia2021
Dr Wei-Yu Lin
Dr Sarah Fordham
Dr Nicola Sunter
Dr Claire Elstob
Dr Yaobo Xu
et al.
Genome-wide association study identifies susceptibility loci for acute myeloid leukemia2021
Professor James Allan
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Author correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia2019
Dr Nicola Sunter
Professor Graham Jackson
Professor James Allan
Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology2019
Professor James Allan
Genetic susceptibility to breast cancer in lymphoma survivors2019
Professor James Allan
Professor Anthony Moorman
Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk2019
Professor James Allan
Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics2019
Professor James Allan
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK92019
Professor James Allan
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia2018
Dr Sarah Fordham
Dr Helen Blair
Dr Claire Elstob
Professor Ruth Plummer
Dr Yvette Drew
et al.
Inhibition of ATR acutely sensitises acute myeloid leukemia cells to nucleoside analogs that target ribonucleotide reductase2018
Dr Lynsey McKenzie
Hasan Issa
Sandeep Potluri
Dr Helen Blair
Asmida Isa
et al.
The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation2018
Professor Anthony Moorman
Professor Julie Irving
Professor James Allan
Professor Christine Harrison FRCPath FMedSci
A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.12017
Dr Aiste McCormick
Gavin Cuthbert
Dr Rachel O'Donnell
Dr Brian Wilson
Huw Thomas
et al.
Functional characterisation of a novel ovarian cancer cell line, NUOC-12017
Dr Nicola Sunter
Dr Andrew Hall
Dr Tryfonia Mainou-Fowler
Professor Graham Jackson
Dr Helen Marr
et al.
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia2017
Dr Nicola Sunter
Professor Graham Jackson
Dr Thahira Rahman
Professor James Allan
Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci2017
Dr David Jamieson
Dr Nicola Sunter
Sara Muro
Dr Nicola Cresti
Julieann Sludden
et al.
Pharmacogenetic association of MBL2 and CD95 polymorphisms with grade 3 infection following adjuvant therapy for breast cancer with doxorubicin and cyclophosphamide2017
Professor Graham Jackson
Professor James Allan
Telomere length is a critical determinant for survival in multiple myeloma2017
Professor James Allan
Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism2016
Dr Victoria Forster
Mohammed Nahari
Dr Natalia Martinez Soria
Amy Bradburn
Dr Sarah Fordham
et al.
The leukemia-associated RUNX1/ETO oncoprotein confers a mutator phenotype2016
Professor James Allan
Whole-exome Sequence Analysis Implicates Rare Il17REL Variants in Familial and Sporadic Inflammatory Bowel Disease2016
Dr Mark Wade
Dr Nicola Sunter
Dr Sarah Fordham
Anna Long
Dino Mašić
et al.
c-MYC is a radiosensitive locus in human breast cells2015
Professor James Allan
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis2015
Fiona Middleton
Dr Miranda Morton
Dr Claire Elstob
Dr Sarah Fordham
Dr Ashleigh Herriott
et al.
Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition2015
Dr Nicola Sunter
Dr Helen Marr
Dr Andrew Hall
Dr Tryfonia Mainou-Fowler
Professor Graham Jackson
et al.
Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk2015
Dr Sarah Fordham
Mike Cole
Professor Julie Irving
Professor James Allan
Cytarabine preferentially induces mutation at specific sequences in the genome which are identifiable in relapsed acute myeloid leukaemia2015
Professor Julie Irving
Elizabeth Matheson
Helen Blair
Marian Case
Isabella Swidenbank
et al.
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition. Blood. 2014;124(23):3420-34302015
Dr Helen Marr
Dr Luke Gaughan
Dr Susan Tudhope
Professor James Allan
Regulation of CD38 in IRF4 in Chronic Lymphocytic Leukaemia2015
Professor James Allan
Second cancers2015
Professor Anthony Moorman
Professor Julie Irving
Professor James Allan
Professor Christine Harrison FRCPath FMedSci
The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2A2015
Dr Victoria Forster
Mohammed Nahari
Dr Natalia Martinez Soria
Amy Bradburn
Hesta McNeill
et al.
The Leukemia-Associated RUNX1/ETO Oncoprotein Confers a Mutator Phenotype2015
Dr Nicola Sunter
Dr Andrew Hall
Dr Tryfonia Mainou-Fowler
Professor Graham Jackson
Professor James Allan
et al.
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia2014
Dr Sarah Fordham
Mike Cole
Professor Julie Irving
Professor James Allan
Cytarabine leaves a mutational fingerprint in relapsing leukemia2014
Professor Julie Irving
Elizabeth Matheson
Dr Helen Blair
Marian Case
Isabella Swidenbank
et al.
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition2014
Professor James Allan
Second Malignant Neoplasms and Cardiovascular Disease Following Radiotherapy2014
Professor James Allan
Telomere dysfunction accurately predicts clinical outcome in chronic lymphocytic leukaemia, even in patients with early stage disease2014
Professor James Allan
Aetiology, genetics and prevention of secondary neoplasms in adult cancer survivors2013
Professor Graham Jackson
Professor Julie Irving
Professor James Allan
Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk2013
Dr Sarah Fordham
Dr Helen Marr
Professor James Allan
Searching for clarity in therapy-related myelodysplastic syndrome/acute myeloid leukemia prognostication2013
Professor Julie Irving
Professor James Allan
Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype2013
Dr Sarah Fordham
Dr Victoria Forster
Professor Graham Jackson
Dr Simon Bomken
Professor James Allan
et al.
A functional variant in the core promoter of the CD95 cell death receptor gene predicts prognosis in acute promyelocytic leukemia2012
Dr Andrea Beyerle
Professor Olaf Heidenreich
Professor James Allan
AML1/ETO Confers a Mutator Phenotype in AML2012
Professor Julie Irving
Professor James Allan
Common genetic variation contributes significantly to the risk of childhood B-cell precursor acute lymphoblastic leukemia2012
Professor James Allan
Second Malignant Neoplasms and Cardiovascular Disease Following Radiotherapy2012
Dr Victoria Forster
Dr Andrea Beyerle
Professor Olaf Heidenreich
Professor James Allan
AML1/ETO Confers a Mutator Phenotype In Acute Myeloid Leukemia Associated with Downregulation of the Base-Excision-Repair Gene OGG12011
Professor Julie Irving
Professor James Allan
DNA mismatch repair status affects cellular response to Ara-C and other anti-leukemic nucleoside analogs2011
Dr Victoria Forster
Amy Bradburn
Professor James Allan
Professor Olaf Heidenreich
The Angiogenic Factor Angiopoietin-1 Is Regulated by the Acute Myeloid Leukemia Fusion Protein AML1/ETO2011
Professor Graham Jackson
Dr Simon Bomken
Professor James Allan
A Functional Polymorphism In the CD95 Cell Death Receptor Associated with Prognosis In Acute Promyelocytic Leukemia2010
Dr Nicola Sunter
Professor Graham Jackson
Dr Simon Bomken
Professor James Allan
A Functional Polymorphism In the CD95 Cell Death Receptor Associated with Prognosis In Acute Promyelocytic Leukemia2010
Professor Graham Jackson
Dr Nicola Sunter
Dr Andrew Hall
Professor Julie Irving
Professor James Allan
et al.
A polymorphism in the 3' UTR of IRF4 linked to susceptibility and pathogenesis in chronic lymphocytic leukaemia and Hodgkin lymphoma has limited impact in multiple myeloma2010
Professor Julie Irving
Professor James Allan
Cellular Response to Cytarabine Is Modulated by the DNA Mismatch Repair Pathway: Implications for Treatment of Acute Myeloid Leukemia2010
Dr Sarah Fordham
Emeritus Professor Keith Scott
Professor Julie Irving
Professor James Allan
Cellular Response to Cytarabine is Modulated by the DNA Mismatch Repair Pathway: Implications for Treatment of Acute Myeloid Leukemia2010
Dr Nicola Sunter
Dr Andrew Hall
Dr Tryfonia Mainou-Fowler
Professor Graham Jackson
Professor James Allan
et al.
Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk2010
Professor James Allan
Genetic variation in the folate metabolic pathway and risk of childhood leukemia2010
Professor Julie Irving
Professor James Allan
Genome-wide homozygosity signatures and childhood acute lymphoblastic leukemia risk2010
Dr Rachel Crossland
Professor Stephen Proctor
Professor James Allan
Mature MicroRNAs Mir 18, 19a, 19b, 17 5p and 92 of the Mir 17 92 Cluster Predict for Treatment Free Survival In Patients with Chronic Lymphocytic Leukaemia2010
Dr Rachel Crossland
Professor Stephen Proctor
Professor James Allan
Dr Tryfonia Mainou-Fowler
Mature MicroRNAs Mir-18,-19a,-19b,-17-5p and-92 of the Mir-17-92 Cluster Predict for Treatment Free Survival In Patients with Chronic Lymphocytic Leukaemia2010
Professor James Allan
Melanocortin 1 receptor (MC1R), pigmentary characteristics and sun exposure: findings from a case-control study of diffuse large B-cell and follicular lymphoma2010
Professor Julie Irving
Professor James Allan
MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukaemia2010
Professor James Allan
Non-Homologous End-Joining Gene Profiling Reveals Distinct Expression Patterns Associated with Lymphoma and Multiple Myeloma2010
Professor James Allan
Testicular Cancer Survivorship: Research Strategies and Recommendations2010
Dr Victoria Forster
Professor James Allan
Professor Olaf Heidenreich
The t(8,21) Fusion Protein AML1/ETO Promotes Susceptibility to Mutation In Acute Myeloid Leukemia2010
Dr Victoria Forster
Professor James Allan
Professor Olaf Heidenreich
The t(8;21) Fusion Protein AML1/ETO Promotes Susceptibility to Mutation In Acute Myeloid Leukemia2010
Professor James Allan
Dr Nicola Sunter
Dr Andrew Hall
Dr Christopher Bacon
Jonathan Pointon
et al.
Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia2010
Professor Julie Irving
Professor James Allan
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk2010
Professor James Allan
[Meeting Abstract] DNA repair dysfunction and genomic instability in therapy-related malignancy2009
Professor James Allan
Association of Molecular Markers With Toxicity Outcomes in a Randomized Trial of Chemotherapy for Advanced Colorectal Cancer: The FOCUS Trial2009
Professor James Allan
Genome-wide association study to identify novel loci associated with therapy-related myeloid leukemia susceptibility2009
Professor Julie Irving
Professor James Allan
Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia2009
Professor James Allan
Polymorphisms in the nucleotide excision repair gene ERCC2/XPD and risk of non-Hodgkin lymphoma2009
Professor James Allan
MDM2 SNP309 and TP53 Arg72Pro interact to alter therapy-related acute myeloid leukemia susceptibility2008
Professor James Allan
Dr Nicola Sunter
Dr Andrew Hall
Dr Tryfonia Mainou-Fowler
Professor Graham Jackson
et al.
A Common Genetic Variant in the 3'UTR of IRF4/MUM1 Associates with Risk of Disease and Poor Prognosis in Chronic Lymphocytic Leukaemia2008
Professor James Allan
A Genome-Wide Analysis to Identify Novel Susceptibility Loci for Therapy-Related Acute Myeloid Leukemia2008
Dr Nicola Sunter
Dr Andrew Hall
Dr Tryfonia Mainou-Fowler
Professor Graham Jackson
Professor James Allan
et al.
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia2008
Professor James Allan
Genetic susceptibility to radiogenic cancer in humans2008
Professor James Allan
Genetic variation in genes expressed in the germinal center and risk of B cell lymphoma among Caucasians2008
Professor James Allan
Influence of DNA repair gene polymorphisms on the initial repair of MMS-induced DNA damage in human lymphocytes as measured by the alkaline comet assay2008
Professor James Allan
MLH1 -93G>A promoter polymorphism and risk of mismatch repair deficient colorectal cancer2008
Professor Graham Jackson
Professor James Allan
Polymorphic MLH1 and risk of cancer after methylating chemotherapy for Hodgkin lymphoma2008
Professor James Allan
Risk of Leukemia Among Survivors of Testicular Cancer: A Population-based Study of 42,722 Patients2008
Professor James Allan
The Genetics of Cancer Survivorship2008
Professor James Allan
A common genetic variant in XPD associates with risk of 5q- and 7q-deleted acute myeloid leukemia2007
Professor James Allan
Deregulation of homologous recombination DNA repair in alkylating agent-treatedstem cell clones: a possible role in the aetiology of chemotherapy-induced leukaemia2006
Professor James Allan
Mechanisms of therapy-related carcinogenesis2005
Professor James Allan
Genetic variation in XPD predicts treatment outcome and risk of acute myeloid leukemia following chemotherapy2004
Professor James Allan
An Intron Splice Acceptor Polymorphism in hMSH2 and Risk of Leukemia after Treatment with Chemotherapeutic Alkylating Agents2003
Professor James Allan
Genetic alterations in bronchial mucosa and plasma DNA from individuals at high risk of lung cancer2001
Professor James Allan
Professor Anthony Moorman
Polymorphism in glutathione S-transferase PI is associated with susceptibility to chemotherapy-induced leukaemia2001