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How the walls come crumbling down: recent structural biochemistry of plant polysaccharide degradation

Lookup NU author(s): Emeritus Professor Harry Gilbert


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The recent years have witnessed considerable developments in the interpretation of the three-dimensional structures of plant polysaccharide-degrading enzymes in the context of their functional specificity. A plethora of new structures of catalytic, carbohydrate-binding and protein-scaffolding modules involved in (hemi)cellulose catabolism has emerged in harness with sophisticated biochemical analysis. Despite significant advances, a full understanding of the intricacies of substrate recognition and catalysis by these diverse and specialised enzymes remains an important goal, especially if the application potential of these biocatalysts is to be fully realised. © 2008 Elsevier Ltd. All rights reserved.

Publication metadata

Author(s): Gilbert HJ, Stalbrand H, Brumer H

Publication type: Article

Publication status: Published

Journal: Current Opinion in Plant Biology

Year: 2008

Volume: 11

Issue: 3

Pages: 338-348

ISSN (print): 1369-5266

ISSN (electronic): 1879-0356

Publisher: Elsevier Ltd., Current Opinion Journals


DOI: 10.1016/j.pbi.2008.03.004


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Funder referenceFunder name
BB/E015190/1Biotechnology and Biological Sciences Research Council
BB/C005074/1Biotechnology and Biological Sciences Research Council