Publications by Emeritus Professor Harry Gilbert - ePrints

Browsing publications by Emeritus Professor Harry Gilbert.

Newcastle Authors	Title	Year
Dr Alan Cartmell Dr Jose Munoz Munoz Dr Jonathan Briggs Dr Didier Ndeh Dr Elisabeth Lowe et al.	Author Correction: A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation	2019
Dr Alan Cartmell Dr Jose Munoz Munoz Dr Jonathan Briggs Dr Didier Ndeh Dr Elisabeth Lowe et al.	A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status forarabinogalactan degradation	2018
Yan Zhu Emeritus Professor Harry Gilbert	Bacteroides thetaiotaomicron generates diverse α-mannosidase activities through subtle evolution of a distal substrate-binding motif	2018
Dr Didier Ndeh Emeritus Professor Harry Gilbert	Biochemistry of complex glycan depolymerisation by the human gut microbiota	2018
Dr Jonathan Briggs Xiaoyang Zhang Dr Didier Ndeh Dr Aurore Labourel Dr Arnaud Basle et al.	Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides	2018
Emeritus Professor Harry Gilbert	Expression system for structural and functional studies of human glycosylation enzymes	2018
Emeritus Professor Harry Gilbert	Expression system for structural and functional studies of human glycosylation enzymes	2018
Emeritus Professor Harry Gilbert	Higher order scaffoldin assembly in Ruminococcus flavefaciens cellulosome is coordinated by a discrete cohesin-dockerin interaction	2018
Emeritus Professor Harry Gilbert	PULDB: The expanded database of Polysaccharide Utilization Loci	2018
Kate Cameron Emeritus Professor Harry Gilbert	Structure-function analyses generate novel specificities to assemble the components of multienzyme bacterial cellulosome complexes	2018
Dr Arnaud Basle Emeritus Professor Harry Gilbert Dr Didier Ndeh	Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016)	2018
Dr Max Temple Dr Fiona Cuskin Dr Arnaud Basle Emeritus Professor Harry Gilbert Dr Elisabeth Lowe et al.	A Bacteroidetes locus dedicated to fungal 1,6-β-glucan degradation: unique substrate conformation drives specificity of the key endo-1,6-β-glucanase	2017
Dr Jose Munoz Munoz Dr Alan Cartmell Dr Arnaud Basle Emeritus Professor Harry Gilbert	An evolutionarily distinct family of polysaccharide lyases removes rhamnose capping of complex arabinogalactan proteins	2017
Emeritus Professor Harry Gilbert	Assembly of Ruminococcus flavefaciens cellulosome revealed by structures of two cohesin-dockerin complexes	2017
Dr Didier Ndeh Dr Artur Rogowski Dr Alan Cartmell Ana De Jesus Vaz Luís Dr Arnaud Basle et al.	Complex pectin metabolism by gut bacteria reveals novel catalytic functions	2017
Emeritus Professor Harry Gilbert	Complexity of the Ruminococcus flavefaciens FD-1 cellulosome reflects an expansion of family-related protein-protein interactions	2017
Dr Alan Cartmell Dr Elisabeth Lowe Dr Arnaud Basle Dr Susan Firbank Dr Didier Ndeh et al.	How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans	2017
Dr Artur Rogowski Carl Morland Emeritus Professor Harry Gilbert	Systems analysis in Cellvibrio japonicus resolves predicted redundancy of β-glucosidases and determines essential physiological functions	2017
Dr Jose Munoz Munoz Dr Alan Cartmell Emeritus Professor Harry Gilbert	Unusual active site location and catalytic apparatus in a glycoside hydrolase family	2017
Emeritus Professor Harry Gilbert	A Novel Carbohydrate-binding Module from Sugar Cane Soil Metagenome Featuring Unique Structural and Carbohydrate Affinity Properties	2016
Dr Fiona Cuskin Emeritus Professor Harry Gilbert	A β-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism	2016
Dr Alan Cartmell Dr Jose Munoz Munoz Emeritus Professor Harry Gilbert	Analysis Human Microbiome Reveals a New Glycoside Hydrolase Family, Which Lacks the Canonical Catalytic Apparatus	2016
Dr Jose Munoz Munoz Dr Alan Cartmell Emeritus Professor Harry Gilbert	Bacteroides thetaiotaomicron requires rhamnose release to grow with Gum Arabic	2016
Dr Imma Venditto Ana De Jesus Vaz Luís Dr Arnaud Basle Emeritus Professor Harry Gilbert Professor William Willats et al.	Complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition	2016
Benedita Pinheiro Kate Cameron Dr Fiona Cuskin Emeritus Professor Harry Gilbert	Diverse specificity of cellulosome attachment to the bacterial cell surface	2016
Emeritus Professor Harry Gilbert	Editorial overview: Carbohydrate–protein interactions and glycosylation: integrating structural biology, informatics and systems modelling to understand glycan structure and glycan-protein interactions	2016
Dr Elisabeth Lowe Dr Fiona Cuskin Dr Max Temple Dr Arnaud Basle Emeritus Professor Harry Gilbert et al.	Fungal cell wall glucan metabolism by Bacteroides in the human gut	2016
Dr Fiona Cuskin Dr Lucy Crouch Dr Arnaud Basle Dr David Bolam Emeritus Professor Harry Gilbert et al.	Pivotal alpha mannosidase generates specificity for N-glycans through requirement for GlcNac at+2 subsite.	2016
Emeritus Professor Harry Gilbert	Single Binding Mode Integration of Hemicellulose-degrading Enzymes via Adaptor Scaffoldins in Ruminococcus flavefaciens Cellulosome	2016
Dr Imma Venditto Ana De Jesus Vaz Luís Dr Julia Schuckel Dr Arnaud Basle Emeritus Professor Harry Gilbert et al.	The complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition	2016
Dr Lucy Crouch Dr Aurore Labourel Emeritus Professor Harry Gilbert	The contribution of non-catalytic carbohydrate binding modules to the activity lytic polysaccharide monooxygenases	2016
Dr Aurore Labourel Dr Lucy Crouch Dr Adam Jackson Dr Artur Rogowski Dr Joseph Gray et al.	The Mechanism by Which Arabinoxylanases Can Recognize Highly Decorated Xylans	2016
Emeritus Professor Harry Gilbert Dr Didier Ndeh Dr Artur Rogowski Dr Fiona Cuskin Dr Elisabeth Lowe et al.	Understanding complex glycan utilization in the human microbiota	2016
Emeritus Professor Harry Gilbert	Automatic prediction of polysaccharide utilization loci in Bacteroidetes species	2015
Emeritus Professor Harry Gilbert	Carbohydrate-binding module assisting glycosynthase-catalysed polymerizations	2015
Kate Cameron Dr Helen Waller Emeritus Professor Harry Gilbert	Cell-surface Attachment of Bacterial Multienzyme Complexes Involves Highly Dynamic Protein-Protein Anchors	2015
Emeritus Professor Harry Gilbert Dr Fiona Cuskin Dr Elisabeth Lowe	Coevolution of yeast mannan digestion: Convergence of the civilized human diet, distal gut microbiome, and host immunity	2015
Kate Cameron Emeritus Professor Harry Gilbert	Combined Crystal Structure of a Type I Cohesin: Mutation and Affinity Binding Studies Reveal Structural Determinants of Cohesin-Dockerin Specificities	2015
Dr Max Temple Emeritus Professor Harry Gilbert	Evidence for a Boat Conformation at the Transition State of GH76 α Normal 0 false false false EN-GB X-NONE X-NONE -1,6-Mannanases-Key Enzymes in Bacterial and Fungal Mannoprotein Metabolism	2015
Dr Imma Venditto Ana De Jesus Vaz Luís Emeritus Professor Harry Gilbert	Family 46 Carbohydrate-binding Modules Contribute to the Enzymatic Hydrolysis of Xyloglucan and β-1,3–1,4-Glucans through Distinct Mechanisms	2015
Dr Artur Rogowski Jon Briggs Dr Elisabeth Lowe Dr Arnaud Basle Carl Morland et al.	Glycan complexity dictates microbial resource allocation in the large intestine	2015
Dr Fiona Cuskin Dr Elisabeth Lowe Dr Max Temple Dr Alan Cartmell Dr Artur Rogowski et al.	Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism	2015
Dr Artur Rogowski Carl Morland Dr Alan Cartmell Dr Lucy Crouch Dr Aurore Labourel et al.	Recognition of xyloglucan by the crystalline cellulose-binding site of a family 3a carbohydrate-binding module	2015
Dr Fiona Cuskin Emeritus Professor Harry Gilbert	Structure of the GH76 alpha-mannanase homolog, BT2949, from the gut symbiont Bacteroides thetaiotaomicron	2015
Dr Fiona Cuskin Dr Arnaud Basle Dr Alison Day Emeritus Professor Harry Gilbert Dr Elisabeth Lowe et al.	The GH130 Family of Mannoside Phosphorylases Contains Glycoside Hydrolases That Target β-1,2-Mannosidic Linkages in Candida Mannan	2015
Thabata Alvarez Emeritus Professor Harry Gilbert	Cloning, purification, crystallization and preliminary X-ray studies of a carbohydrate-binding module (CBM_E1) derived from sugarcane soil metagenome	2014
Dr Adam Jackson Dr Elisabeth Lowe Emeritus Professor Harry Gilbert	Combined Inhibitor Free-Energy Landscape and Structural Analysis Reports on the Mannosidase Conformational Coordinate	2014
Emeritus Professor Harry Gilbert	Editorial overview: Carbohydrate-protein interactions: The future is taking shape	2014
Dr Artur Rogowski Dr Arnaud Basle Dr Alexandra Solovyova Emeritus Professor Harry Gilbert Dr David Bolam et al.	Evidence That GH115 alpha-Glucuronidase Activity, Which Is Required to Degrade Plant Biomass, Is Dependent on Conformational Flexibility	2014
Emeritus Professor Harry Gilbert	Mechanistic Strategies for Catalysis Adopted by Evolutionary Distinct Family 43 Arabinanases	2014
Emeritus Professor Harry Gilbert	Recovery and fine structure variability of RGII sub-domains in wine (Vitis vinifera Merlot)	2014
Emeritus Professor Harry Gilbert	Structure- and context-based analysis of the GxGYxYP family reveals a new putative class of Glycoside Hydrolase	2014
Dr Lucy Crouch Dr Aurore Labourel Emeritus Professor Harry Gilbert	Systems biology defines the biological significance of redox-active proteins during cellulose degradation in an aerobic bacterium	2014
Xiaoyang Zhang Dr Artur Rogowski Emeritus Professor Harry Gilbert	Understanding How the Complex Molecular Architecture of Mannan-degrading Hydrolases Contributes to Plant Cell Wall Degradation	2014
Emeritus Professor Harry Gilbert	Advances in understanding the molecular basis of plant cell wall polysaccharide recognition by carbohydrate-binding modules	2013
Dr Max Temple Emeritus Professor Harry Gilbert	Overproduction, purification, crystallization and preliminary X-ray characterization of the C-terminal family 65 carbohydrate-binding module (CBM65B) of endoglucanase Cel5A from Eubacterium cellulosolvens	2013
Dr Adam Jackson Emeritus Professor Harry Gilbert	The Structure of a Streptomyces avermitilis alpha-L-Rhamnosidase Reveals a Novel Carbohydrate-binding Module CBM67 within the Six-domain Arrangement	2013
Dr Max Temple Dr Artur Rogowski Dr Arnaud Basle Emeritus Professor Harry Gilbert	Understanding How Noncatalytic Carbohydrate Binding Modules Can Display Specificity for Xyloglucan	2013
Emeritus Professor Harry Gilbert	Escherichia coli Expression, Purification, Crystallization, and Structure Determination of Bacterial Cohesin–Dockerin Complexes	2012
Emeritus Professor Harry Gilbert	Designer-oligosaccharide microarrays to decipher ligands in mammalian and prokaryotic glucan-recognition systems	2012
Dr Fiona Cuskin Dr James Flint Carl Morland Dr Arnaud Basle Dr Alexandra Solovyova et al.	How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity	2012
Dr Adam Jackson Emeritus Professor Harry Gilbert	Influence of a Mannan Binding Family 32 Carbohydrate Binding Module on the Activity of the Appended Mannanase	2012
Dr Artur Rogowski Dr Adam Jackson Professor Rick Lewis Emeritus Professor Harry Gilbert Dr Jon Marles-Wright et al.	Introducing endo-xylanase activity into an exo-acting arabinofuranosidase that targets side chains	2012
Dr David Bolam Emeritus Professor Harry Gilbert	Novel Clostridium thermocellum Type I Cohesin-Dockerin Complexes Reveal a Single Binding Mode	2012
Emeritus Professor Harry Gilbert	The Reaction Coordinate of a Bacterial GH47 alpha-Mannosidase: A Combined Quantum Mechanical and Structural Approach	2012
Cedric Montanier Dr James Flint Dr Arnaud Basle Professor Rick Lewis Emeritus Professor Harry Gilbert et al.	A novel, noncatalytic carbohydrate-binding module displays specificity for galactose-containing polysaccharides through calcium-mediated oligomerization	2011
Dr Elisabeth Lowe Emeritus Professor Harry Gilbert Dr David Bolam	Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts	2011
Emeritus Professor Harry Gilbert	Structural and enzymatic characterization of a glycoside hydrolase family 31 alpha-xylosidase from Cellvibrio japonicus involved in xyloglucan saccharification	2011
Alan Cartmell Emeritus Professor Harry Gilbert	Structural insights into a unique cellulase fold and mechanism of cellulose hydrolysis	2011
Professor Rick Lewis Emeritus Professor Harry Gilbert	Structure and Function of an Arabinoxylan-specific Xylanase	2011
Dr Morten Nielsen Dr Louise Tailford Dr James Flint Dr Claire Dumon Emeritus Professor Harry Gilbert et al.	Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase	2011
Alan Cartmell Lauren McKee Professor Rick Lewis Emeritus Professor Harry Gilbert Dr Jon Marles-Wright et al.	The Structure and Function of an Arabinan-specific α-1,2-Arabinofuranosidase Identified from Screening the Activities of Bacterial GH43 Glycoside Hydrolases	2011
Dr Artur Rogowski Emeritus Professor Harry Gilbert	Carbohydrate-binding modules promote the enzymatic deconstruction of intact plant cell walls by targeting and proximity effects	2010
Cedric Montanier Dr James Flint Dr David Bolam He Fang Xie Ziyuan Liu et al.	Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-dependent Carbohydrate Binding Modules	2010
Dr Claire Dumon Emeritus Professor Harry Gilbert	Mechanistic insights into a Ca²⁺-dependent family of α-mannosidases in a human gut symbiont	2010
Professor Liam Donaldson Dr Artur Rogowski Emeritus Professor Harry Gilbert Professor William Willats	Restricted access of proteins to mannan polysaccharides in intact plant cell walls	2010
Cedric Montanier Dr Claire Dumon Dr James Flint Emeritus Professor Harry Gilbert	Signature Active Site Architectures Illuminate the Molecular Basis for Ligand Specificity in Family 35 Carbohydrate Binding Module	2010
Yan Zhu Emeritus Professor Harry Gilbert	Structure and Kinetic Investigation of Streptococcus pyogenes Family GH38 alpha-Mannosidase	2010
Dr Artur Rogowski Alan Cartmell Emeritus Professor Harry Gilbert	Analysis of the Structural and Functional Diversity of Plant Cell Wall Specific Family 6 Carbohydrate Binding Modules	2009
Emeritus Professor Harry Gilbert	Developmental complexity of arabinan polysaccharides and their processing in plant cell walls	2009
Dr Artur Rogowski Emeritus Professor Harry Gilbert	Enzymatic treatments reveal differential capacities for xylan recognition and degradation in primary and secondary plant cell walls	2009
Dr Claire Dumon Dr James Flint Dr Susan Firbank Professor Rick Lewis Emeritus Professor Harry Gilbert et al.	Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function	2009
Emeritus Professor Harry Gilbert Dr David Bolam	Family 6 carbohydrate-binding modules display multiple beta 1,3-linked glucan-specific binding interfaces	2009
Benedita Pinheiro Emeritus Professor Harry Gilbert Dr David Bolam	Functional insights into the role of novel type I cohesin and dockerin domains from Clostridium thermocellum	2009
Dr Kaveh Emami Dr Topakas Topakas Tibor Nagy Joanna Henshaw Dr Kelly Jackson et al.	Regulation of the xylan-degrading apparatus of Cellvibrio japonicus by a novel two-component system	2009
Cedric Montanier Dr James Flint Benedita Pinheiro Carl Morland Alan Cartmell et al.	The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions	2009
Dr Louise Tailford Dr James Flint Carl Morland Emeritus Professor Harry Gilbert	Understanding How Diverse beta-Mannanases Recognize Heterogeneous Substrates	2009
Emeritus Professor Harry Gilbert	Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40T	2008
Dr Joseph Newman Professor Rick Lewis Emeritus Professor Harry Gilbert Dr James Flint	Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides insights into the mechanism of substrate recognition	2008
Dr Claire Dumon Dr James Flint Professor Rick Lewis Professor Jeremy Lakey Carl Morland et al.	Engineering hyperthermostability into a GH₁₁ xylanase is mediated by subtle changes to protein structure	2008
Emeritus Professor Harry Gilbert	How the walls come crumbling down: recent structural biochemistry of plant polysaccharide degradation	2008
Dr Louise Tailford Emeritus Professor Harry Gilbert	Insights into plant cell wall degradation from the genome sequence of the soil bacterium Cellvibrio japonicus	2008
Alan Cartmell Emeritus Professor Harry Gilbert	Probing the β-1,3:1,4 glucanase, CtLic26A, with a thio-oligosaccharide and enzyme variants	2008
Dr Louise Tailford Dr Claire Dumon Carl Morland Emeritus Professor Harry Gilbert	Structural and biochemical evidence for a boat-like transition state in β-mannosidases	2008
Emeritus Professor Harry Gilbert	Sus out Sugars in	2008
Alan Cartmell Dr Topakas Topakas Emeritus Professor Harry Gilbert	The Cellvibrio japonicus mannanase CjMan26C displays a unique exo-mode of action that is conferred by subtle changes to the distal region of the active site	2008
Benedita Pinheiro Dr Mark Proctor Emeritus Professor Harry Gilbert	The Clostridium cellulolyticum Dockerin Displays a Dual Binding Mode for Its Cohesin Partner	2008
Emeritus Professor Harry Gilbert	Cellulosomes: Microbial nanomachines that display plasticity in quaternary structure	2007
Tibor Nagy Emeritus Professor Harry Gilbert	Characterization of a Double Dockerin from the Cellulosome of the Anaerobic Fungus Piromyces equi	2007
Tibor Nagy Dr Mark Proctor Emeritus Professor Harry Gilbert	Evidence for a dual binding mode of dockerin modules to cohesins	2007
Dr Louise Tailford Dr Claire Dumon Emeritus Professor Harry Gilbert	Mannose foraging by Bacteroides thetaiotaomicron: Structure and specificity of the β-mannosidase, BtMan2A	2007
Emeritus Professor Harry Gilbert	Novel xylan-binding properties of an engineered family 4 carbohydrate-binding module	2007
Emeritus Professor Harry Gilbert	Promiscuous, non-catalytic, tandem carbohydrate-binding modules modulate the cell-wall structure and development of transgenic tobacco (Nicotiana tabacum) plants	2007
Dr David Bolam Dr Mark Proctor Emeritus Professor Harry Gilbert	The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity	2007
Dr James Flint Dr David Bolam Emeritus Professor Harry Gilbert	Differential recognition of plant cell walls by microbial xylan-specific carbohydrate-binding modules	2006
Dr Louise Tailford Emeritus Professor Harry Gilbert	Enzymatic fingerprinting of Arabidopsis pectic polysaccharides using polysaccharide analysis by carbohydrate gel electrophoresis (PACE)	2006
Joanna Henshaw Dr David Bolam Emeritus Professor Harry Gilbert	Family 6 carbohydrate binding modules in β-agarases display exquisite selectivity for the non-reducing termini of agarose chains	2006
Carl Morland Dr Louise Tailford Emeritus Professor Harry Gilbert	Galactomannan hydrolysis and mannose metabolism in Cellvibrio mixtus	2006
Dr Mark Proctor Dr David Bolam Emeritus Professor Harry Gilbert	Insights into the Synthesis of Lipopolysaccharide and Antibiotics through the Structures of Two Retaining Glycosyltransferases from Family GT4	2006
Emeritus Professor Harry Gilbert	Novel modular enzymes encoded by a cellulase gene cluster in Cellvibrio mixtus	2006
He Fang Xie Dr James Flint Professor Jeremy Lakey Professor Rick Lewis Emeritus Professor Harry Gilbert et al.	Probing the Structural Basis for the Difference in Thermostability Displayed by Family 10 Xylanases	2006
Dr Edward Taylor Emeritus Professor Harry Gilbert	Structural insight into the ligand specificity of a thermostable family 51 arabinofuranosidase, Araf51, from Clostridium thermocellum	2006
Emeritus Professor Harry Gilbert	Substrate distortion by a lichenase highlights the different conformational itineraries harnessed by related glycoside hydrolases	2006
Dr James Flint Dr David Bolam Emeritus Professor Harry Gilbert	Understanding the biological rationale for the diversity of cellulose-directed carbohydrate-binding modules in prokaryotic enzymes	2006
Emeritus Professor Harry Gilbert Dr David Bolam	Xyloglucan is recognized by carbohydrate-binding modules that interact with β-glucan chains	2006
Dr James Flint Professor Rick Lewis Emeritus Professor Harry Gilbert Dr James Murray	A family 10 Thermoascus aurantiacus xylanase utilizes arabinose decorations of xylan as significant substrate specificity determinants	2005
Carl Morland Emeritus Professor Harry Gilbert	Family 6 carbohydrate binding modules recognize the non-reducing end of β-1,3-linked glucans by presenting a unique ligand binding surface	2005
Dr Natalie Ferry Carl Morland Emeritus Professor Harry Gilbert	How family 26 glycoside hydrolases orchestrate catalysis on different polysaccharides: Structure and activity of a Clostridium thermocellum lichenase, CtLic26A	2005
Dr Alexandra Carvalho Emeritus Professor Harry Gilbert	Insights into the structural determinants of cohesin - Dockerin specificity revealed by the crystal structure of the type II cohesin from Clostridium thermocellum SdbA	2005
Gavin Pell Emeritus Professor Harry Gilbert	Mycobacterium tuberculosis strains possess functional cellulases	2005
Dr Mark Proctor Dr David Bolam Emeritus Professor Harry Gilbert	Probing the breadth of macrolide glycosyltransferases: In vitro remodeling of a polyketide antibiotic creates active bacterial uptake and enhances potency	2005
Dr James Flint Dr David Bolam Dr Edward Taylor Emeritus Professor Harry Gilbert	Probing the mechanism of ligand recognition in family 29 carbohydrate-binding modules	2005
Dr James Flint Dr David Bolam Dr Louise Tailford Emeritus Professor Harry Gilbert	Structural dissection and high-throughput screening of mannosylglycerate synthase	2005
Dr David Bolam Gavin Pell Emeritus Professor Harry Gilbert	Structure of a mannan-specific family 35 carbohydrate-binding module: Evidence for significant conformational changes upon ligand binding	2005
Dr Mark Proctor Dr Edward Taylor Dr Ruth Lloyd Emeritus Professor Harry Gilbert	Tailored catalysts for plant cell-wall degradation: Redesigning the exo/endo preference of Cellvibrio japonicus arabinanase 43A	2005
Dr Mark Proctor Dr Edward Taylor Dr Ruth Lloyd Emeritus Professor Harry Gilbert	Tailored catalysts for plant cell-wall degradation: redesigning the exo/endo preference of Cellvibrio japonicus arabinanase 43A	2005
Dr Trudy Netherwood Professor Anthony O'Donnell Professor John Mathers Emeritus Professor Harry Gilbert	Assessing the survival of transgenic plant DNA in the human gastrointestinal tract	2004
Dr David Bolam Emeritus Professor Harry Gilbert	Carbohydrate-binding modules: Fine-tuning polysaccharide recognition	2004
Carl Morland Emeritus Professor Harry Gilbert	Common inhibition of both β-glucosidases and β-mannosidases by isofagomine lactam reflects different conformational itineraries for pyranoside hydrolysis	2004
Emeritus Professor Harry Gilbert Dr David Bolam	Glycoside hydrolase carbohydrate-binding modules as molecular probes for the analysis of plant cell wall polymers	2004
Emeritus Professor Harry Gilbert	Inactivated enzymes as probes of the structure of arabinoxylans as observed by atomic force microscopy	2004
Emeritus Professor Harry Gilbert Professor Anthony O'Donnell Professor John Mathers	'Informative' horizontal gene transfer	2004
Gavin Pell Dr Louise Tailford Emeritus Professor Harry Gilbert	Insights into the molecular determinants of substrate specificity in glycoside hydrolase family 5 revealed by the crystal structure and kinetics of Cellvibrio mixtus mannosidase 5A	2004
Dr James Flint Emeritus Professor Harry Gilbert Dr David Bolam	Ligand-mediated dimerization of a carbohydrate-binding module reveals a novel mechanism for protein-carbohydrate recognition	2004
Dr David Bolam Emeritus Professor Harry Gilbert	Reduction of starch granule size by expression of an engineered tandem starch-binding domain in potato plants	2004
Gavin Pell Lorand Szabo He Fang Xie Emeritus Professor Harry Gilbert	Structural and biochemical analysis of Cellvibrio japonicus Xylanase 10C: How variation in substrate-binding cleft influences the catalytic profile of family GH-10 xylanases	2004
Joanna Henshaw Dr David Bolam Emeritus Professor Harry Gilbert	The crystal structure of the family 6 carbohydrate binding module from Cellvibrio mixtus endoglucanase 5A in complex with oligosaccharides reveals two distinct binding sites with different ligand specificities	2004
Emeritus Professor Harry Gilbert	The dual nature of the wheat xylanase protein inhibitor XIP-I: Structural basis for the inhibition of family 10 and family 11 xylanases	2004
Dr David Bolam Emeritus Professor Harry Gilbert	The family 11 carbohydrate-binding module of Clostridium thermocellum Lic26A-Cel5E accommodates β-1,4- and β-1,3-1,4-mixed linked glucans at a single binding site	2004
Joanna Henshaw Dr David Bolam Emeritus Professor Harry Gilbert	The family 6 carbohydrate binding module CmCBM6-2 contains two ligand-binding sites with distinct specificities	2004
Gavin Pell Dr Edward Taylor Tibor Nagy Emeritus Professor Harry Gilbert	The Mechanisms by Which Family 10 Glycoside Hydrolases Bind Decorated Substrates	2004
Emeritus Professor Harry Gilbert	The N-terminal family 22 carbohydrate-binding module of xylanase 10B of Clostridium themocellum is not a thermostabilizing domain	2004
Simon Andrews Dr Edward Taylor Gavin Pell Professor Jeremy Lakey Emeritus Professor Harry Gilbert et al.	The use of forced protein evolution to investigate and improve stability of family 10 xylanases: The production of Ca^₂₊independent stable xylanases	2004
Dr David Bolam Gavin Pell Deborah Hogg Greta Galbraith Emeritus Professor Harry Gilbert et al.	X4 modules represent a new family of carbohydrate-binding modules that display novel properties	2004
Emeritus Professor Harry Gilbert	Cel6A, a major exoglucanase from the cellulosome of the anaerobic fungi Piromyces sp. E2 and Piromyces equi	2003
Emeritus Professor Harry Gilbert	Cell, a noncellulosomal family 9 enzyme from Clostridium thermocellum, is a processive endoglucanase that degrades crystalline cellulose	2003
Tibor Nagy Emeritus Professor Harry Gilbert	Cellulosome assembly revealed by the crystal structure of the cohesin-dockerin complex	2003
Gavin Pell Emeritus Professor Harry Gilbert	Distortion of a cellobio-derived isofagomine highlights the potential conformational itinerary of inverting β-glucosidases	2003
Lorand Szabo Emeritus Professor Harry Gilbert	Expansion of the glycosynthase repertoire to produce defined manno-oligosaccharides	2003
Emeritus Professor Harry Gilbert	How carbohydrate binding modules overcome ligand complexity	2003
Gavin Pell Huamao Du Emeritus Professor Harry Gilbert Dr David Bolam	Importance of hydrophobic and polar residues in ligand binding in the family 15 carbohydrate-binding module from Cellvibrio japonicus Xyn10C	2003
Gavin Pell Emeritus Professor Harry Gilbert	Multifunctional xylooligosaccharide/cephalosporin C deacetylase revealed by the hexameric structure of the Bacillus subtilis enzyme at 1.9 Å resolution	2003
Deborah Hogg Gavin Pell Emeritus Professor Harry Gilbert	The modular architecture of Cellvibrio japonicus mannanases in glycoside hydrolase families 5 and 26 points to differences in their role in mannan degradation	2003
Tibor Nagy Professor Jeremy Lakey Dr David Bolam Emeritus Professor Harry Gilbert	The α-Glucuronidase, GlcA67A, of Cellvibrio japonicus utilizes the carboxylate and methyl groups of aldobiouronic acid as important substrate recognition determinants	2003
Emeritus Professor Harry Gilbert Dr David Bolam	Calcium binding and thermostability of carbohydrate binding module CBM4-2 of Xyn10A from Rhodothermus marinus	2002
Emeritus Professor Harry Gilbert	Cellvibrio japonicus alpha-L-arabinanase 43A has a novel five-blade beta-propeller fold	2002
Professor Anthony O'Donnell Dr Trudy Netherwood Emeritus Professor Harry Gilbert Professor John Mathers	Degradation of transgenic DNA from genetically modified soya and maize in human intestinal simulations	2002
Dr Kaveh Emami Tibor Nagy Emeritus Professor Harry Gilbert	Evidence for temporal regulation of the two Pseudomonas cellulosa xylanases belonging to glycoside hydrolase family 11	2002
Dr David Bolam Lorand Szabo Dr Vincent McKie Emeritus Professor Harry Gilbert	Promiscuity in ligand-binding: The three-dimensional structure of a Piromyces carbohydrate-binding module, CBM29-2, in complex with cello-and mannohexaose	2002
Emeritus Professor Harry Gilbert Lorand Szabo	Substrate distortion by β-mannanase: Snapshots of the Michaelis and covalent-intermediate complexes suggest a B2,5 conformation for the transition state	2002
Emeritus Professor Harry Gilbert	The major component of the cellulosomes of anaerobic fungi from the genus Piromyces is a family 48 glycoside hydrolase	2002
Tibor Nagy Dr Kaveh Emami Emeritus Professor Harry Gilbert	The membrane-bound α-glucuronidase from Pseudomonas cellulosa hydrolyzes 4-O-methyl-D-glucuronoxylooligosaccharides but not 4-O-methyl-D-glucuronoxylan	2002
Emeritus Professor Harry Gilbert	The solution structure of the CBM4-2 carbohydrate binding module from a thermostable Rhodothermus marinus xylanase	2002
Tibor Nagy Emeritus Professor Harry Gilbert	The structural basis for catalysis and specificity of the Pseudomonas cellulosa alpha-glucuronidase, GlcA67A	2002
Marie-helene Beylot Dr Kaveh Emami Dr Vincent McKie Emeritus Professor Harry Gilbert Gavin Pell et al.	Pseudomonas cellulosa expresses a single membrane-bound glycoside hydrolase family 51 arabinofuranosidase	2001
Dr Vincent McKie Emeritus Professor Harry Gilbert	A new family of rhamnogalacturonan lyases contains an enzyme that binds to cellulose	2001
Dr David Bolam Emeritus Professor Harry Gilbert	A Novel Carbohydrate-binding Protein Is a Component of the Plant Cell Wall-degrading Complex of Piromyces equi	2001
Tibor Nagy Emeritus Professor Harry Gilbert	Characterization of a cellulosome dockerin domain from the anaerobic fungus Piromyces equi	2001
He Fang Xie Emeritus Professor Harry Gilbert Dr David Bolam	Clostridium thermocellum Xyn10B carbohydrate-binding module 22-2: The role of conserved amino acids in ligand binding	2001
Deborah Hogg Dr David Bolam Dr Vincent McKie Emeritus Professor Harry Gilbert	Crystal Structure of Mannanase 26A from Pseudomonas cellulosa and Analysis of Residues Involved in Substrate Binding	2001
Dr David Bolam Emeritus Professor Harry Gilbert	Evidence for synergy between family 2b carbohydrate binding modules in Cellulomonas fimi Xylanase 11A	2001
Simon Andrews Emeritus Professor Harry Gilbert	Influence of the aglycone region of the substrate binding cleft of Pseudomonas xylanase 10A on catalysis	2001
Lorand Szabo He Fang Xie Dr David Bolam Emeritus Professor Harry Gilbert	Structure of a Family 15 Carbohydrate-binding Module in Complex with Xylopentaose	2001
Lorand Szabo He Fang Xie Dr David Bolam Emeritus Professor Harry Gilbert	Structure of a family 15 carbohydrate-binding module in complex with xylopentaose: Evidence that xylan binds in an approximate 3-fold helical conformation	2001
Marie-helene Beylot Dr Vincent McKie Emeritus Professor Harry Gilbert	The Pseudomonas cellulosa glycoside hydrolase family 51 arabinofuranosidase exhibits wide substrate specificity	2001
Dr David Bolam Emeritus Professor Harry Gilbert	The Location of the Ligand-binding Site of Carbohydrate-binding Modules That Have Evolved from a Common Sequence Is Not Conserved	2001
Emeritus Professor Harry Gilbert	A comparison of enzyme-aided bleaching of softwood paper pulp using combinations of xylanase, mannanase and α-galactosidase	2000
Emeritus Professor Harry Gilbert Dr Vincent McKie Tibor Nagy Helen Fernandes	A novel Cellvibrio mixtus family 10 xylanase that is both intracellular and expressed under non-inducing conditions	2000
Emeritus Professor Harry Gilbert	Carbohydrate-binding modules from a thermostable Rhodothermus marinus xylanase: Cloning, expression and binding studies	2000
Emeritus Professor Harry Gilbert	Primary sequence and enzymic properties of two modular endoglucanases, Cel5A and Cel45A, from the anaerobic fungus Piromyces equi	2000
Lorand Szabo Tibor Nagy Emeritus Professor Harry Gilbert	Solution structure of the CBM10 cellulose binding module from Pseudomonas Xylanase A	2000
Simon Andrews Professor Jeremy Lakey Emeritus Professor Harry Gilbert	Substrate specificity in glycoside hydrolase family 10: Tyrosine 87 and leucine 314 play a pivotal role in discriminating between glucose and xylose binding in the proximal active site of pseudomonas cellulosa xylanase 10A	2000
He Fang Xie Dr David Bolam Emeritus Professor Harry Gilbert	The structural basis for the ligand specificity of family 2 carbohydrate-binding modules	2000
Dr David Bolam Emeritus Professor Harry Gilbert	The X6 'thermostabilizing' domains of xylanases are carbohydrate-binding modules: Structure and biochemistry of the Clostridium thermocellum X6b domain	2000
Lorand Szabo Tibor Nagy Emeritus Professor Harry Gilbert	Trp22, Trp24, and Tyr8 play a pivotal role in the binding of the family 10 cellulose-binding module from Pseudomonas xylanase A to insoluble ligands	2000
Dr Alison Park Emeritus Professor Harry Gilbert	α-Galactosidase A from Pseudomonas fluorescens subsp. cellulosa: Cloning, high level expression and its role in galactomannan hydrolysis	2000
Emeritus Professor Harry Gilbert	A family 26 mannanase produced by Clostridium thermocellum as a component of the cellulosome contains a domain which is conserved in mannanases from anaerobic fungi	1999
Dr David Bolam Emeritus Professor Harry Gilbert	A family IIb xylan-binding domain has a similar secondary structure to a homologous family IIa cellulose-binding domain but different ligand specificity	1999
Emeritus Professor Harry Gilbert	A modular cinnamoyl ester hydrolase from the anaerobic fungus Piromyces equi acts synergistically with xylanase and is part of a multiprotein cellulose-binding cellulase-hemicellulase complex	1999
Professor Simi Ali Emeritus Professor Harry Gilbert Emeritus Professor Barry Hirst Dr Judith Hall	Bacterial xylanase expression in mammalian cells and transgenic mice	1999
Emeritus Professor Harry Gilbert	Crystallization and preliminary X-ray analysis of arabinanase A from Pseudomonas fluorescens subspecies cellulosa	1999
Dr Trudy Netherwood Professor Anthony O'Donnell Emeritus Professor Harry Gilbert	Gene transfer in the gastrointestinal tract	1999
Emeritus Professor Harry Gilbert	Homologous xylanases from Clostridium thermocellum: evidence for bi-functional activity, synergism between xylanase catalytic modules and the presence of xylan-binding domains in enzyme complexes	1999
Dr Trudy Netherwood Emeritus Professor Harry Gilbert Professor Anthony O'Donnell	Probiotics shown to change bacterial community structure in the avian gastrointestinal tract	1999
Emeritus Professor Harry Gilbert	The starch-binding domain from glucoamylase disrupts the structure of starch	1999
Dr David Bolam Emeritus Professor Harry Gilbert	The type II and X cellulose-binding domains of Pseudomonas xylanase A potentiate catalytic activity against complex substrates by a common mechanism	1999
Dr David Bolam Emeritus Professor Harry Gilbert	Pseudomonas cellulose-binding domains mediate their effects by increasing enzyme substrate proximity	1998
Professor Dianne Ford Professor David Thwaites Professor Nicholas Simmons Emeritus Professor Harry Gilbert Emeritus Professor Barry Hirst et al.	Substrate upregulation of the human small intestinal peptide transporter, hPepT1	1998
Carl Morland Professor Anthony O'Donnell Emeritus Professor Harry Gilbert	Calcium protects a mesophilic xylanase from proteinase inactivation and thermal unfolding	1997
Dr David Bolam Emeritus Professor Harry Gilbert	Cellulose binding domains and linker sequences potentiate the activity of hemicellulases against complex substrates	1997
Dr David Bolam Dr Richard Virden Professor Jeremy Lakey Emeritus Professor Harry Gilbert	Mannanase A from Pseudomonas fluorescens ssp. cellulosa is a retaining glycosyl hydrolase in which E212 and E320 are the putative catalytic residues	1996