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Re-emergence of tuberculosis: strategies and treatment

Lookup NU author(s): Dr Laurent Kremer, Professor Del Besra


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Tuberculosis (TB) was declared a global emergency by the WHO in 1993. Approximately one third of the world's population is infected with Mycobacterium tuberculosis. Despite the availability of effective chemotherapy, 3.5 million TB deaths occur each year. In addition to this human cost, TB also represents a significant economic burden for developing countries. The worldwide spread of TB is mainly caused by the emergence of multidrug-resistant (MDR) M. tuberculosis strains, thus underlining the need for novel antimycobacterial drugs with improved efficacy. Research in TB chemotherapy, as well as in vaccine development, has entered an intense phase in an attempt to combat this disease.

Publication metadata

Author(s): Kremer L, Besra GS

Publication type: Editorial

Publication status: Published

Journal: Expert Opinion on Investigational Drugs

Year: 2002

Volume: 11

Issue: 2

Pages: 153-157

ISSN (print): 1354-3784

ISSN (electronic): 1744-7658

Publisher: Informa Healthcare


DOI: 10.1517/13543784.11.2.153