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Lookup NU author(s): Professor David Ellison
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April 2005. A woman aged 24 years presented with symptoms related to a tumor in the fourth ventricle. Cytologically, the tumor was biphasic with areas typical of a classic ependymoma, including rosettes, and other areas containing grossly atypical giant cells. Many tumor cells were GFAP-positive and ultrastructural examination revealed microvilli and cilia. The histopathologic abnormalities place this tumor among the ependymomas. Its focal giant cell phenotype is very rare, but has been reported in 4 intracranial or filum ependymomas.
Author(s): Pal P, Fernandes H, Ellison DW
Publication type: Article
Publication status: Published
Journal: Brain Pathology
ISSN (print): 1015-6305
ISSN (electronic): 1750-3639
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