Publications by Professor David Ellison - ePrints

Browsing publications by Professor David Ellison.

Newcastle Authors	Title	Year
Professor Steven Clifford Professor David Ellison	Medulloblastoma	2019
Professor Simon Bailey Professor David Ellison Professor Steven Clifford	An Exploration of Associations between Health Related Quality of Life and Medulloblastoma Molecular Subgroup Status in Survivors from the SIOP UKCCSG PNET3 Trial	2014
Dr Janet Lindsey Dr Ed Schwalbe Dr James Hayden Professor David Ellison Dr Daniel Williamson et al.	Cross-Species Epigenetics Identifies a Critial Role for VAV1 in the Maintenance of Sonic Hedgehog Subgroup Medulloblastomas	2014
Professor Simon Bailey Professor David Ellison Professor Steven Clifford	Improved health-related quality of life outcomes associated with SHH subgroup medulloblastoma in SIOP-UKCCSG PNET3 trial survivors	2014
Dr Sarra Ryan Dr Ed Schwalbe Mike Cole Yuan Lu Dr Meryl Lusher et al.	MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma	2012
Dr Ed Schwalbe Dr Janet Lindsey Dr Daniel Williamson Kieran O'Toole Dr Meryl Lusher et al.	Epigenetic sub-classification and risk-stratification of medulloblastoma using DNA methylomics	2012
Professor Steven Clifford Professor David Ellison Dr Richard Gilbertson	Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas	2012
Professor Steven Clifford Professor David Ellison Dr Richard Gilbertson	Molecular subgroups of medulloblastoma: the current consensus	2012
Professor David Ellison Dr Hisham Megahed Dr Meryl Lusher Dr Sarra Ryan Professor Simon Bailey et al.	Definition of Disease-Risk Stratification Groups in Childhood Medulloblastoma Using Combined Clinical, Pathologic, and Molecular Variables	2011
Professor David Ellison Sarah Nicholson Professor Simon Bailey Professor Steven Clifford Dr Richard Gilbertson et al.	Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups	2011
Dr Ed Schwalbe Dr Janet Lindsey Debbie Straughton Mike Cole Dr Hisham Megahed et al.	Rapid Diagnosis of Medulloblastoma Molecular Subgroups	2011
Dr Janet Lindsey Dr Rebecca Hill Dr Hisham Megahed Dr Meryl Lusher Dr Ed Schwalbe et al.	TP53 Mutations in Favorable-Risk Wnt/Wingless-Subtype Medulloblastomas	2011
Professor David Ellison Dr Hisham Megahed Dr Sarra Ryan Dr Meryl Lusher Sarah Nicholson et al.	Clinical, pathological, and molecular variables define risk-stratification groups in childhood medulloblastoma	2010
Dr Vikki Rand Professor David Ellison Dr Richard Gilbertson	Cross-species genomics matches driver mutations and cell compartments to model ependymoma	2010
Dr Jun Ma Professor Simon Bailey Professor David Ellison	MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas	2010
Professor Steven Clifford Dr Sarra Ryan Mike Cole Dr Meryl Lusher Kieran O'Toole et al.	MYC gene family amplification and expression in childhood medulloblastoma: Biological significance and utility for high-risk disease stratification	2010
Dr Janet Lindsey Professor Steven Clifford Professor David Ellison Dr Richard Gilbertson	Subtypes of medulloblastoma have distinct developmental origins	2010
Professor David Ellison Professor Simon Bailey	Activation of the MAPK Pathway: A Signature Genetic Defect in Posterior Fossa Pilocytic Astrocytomas	2009
Dr Sarra Ryan Professor David Elliott Professor David Ellison Professor Simon Bailey Professor Steven Clifford et al.	Amplification and overexpression of Hsa-miR-3ob, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma	2009
Professor Steven Clifford Kieran O'Toole Professor David Ellison	Chromosome 1q gain is not associated with a poor outcome in childhood medulloblastoma: requirements for the validation of potential prognostic biomarkers	2009
Dr James Hayden Professor David Ellison Professor Simon Bailey Professor Steven Clifford	Frequent IDH1 mutations in supratentorial primitive neuroectodermal tumors (sPNET) of adults but not children	2009
Dr Helen Lucraft Professor David Ellison	Impact of radiotherapy parameters on outcome for patients with supratentorial primitive neuro-ectodermal tumours entered into the SIOP/UKCCSG PNET 3 study	2009
Professor Steven Clifford Professor David Ellison Kieran O'Toole	Improved Stratification of Standard Risk Medulloblastoma Patients by Clinical and Biological Prognostic Factors	2009
Professor Steven Clifford Professor David Ellison	Novel mechanisms of gene disruption at the medulloblastoma isodicentric 17p11 breakpoint	2009
Jennifer Anderton Dr Janet Lindsey Dr Meryl Lusher Dr Richard Gilbertson Professor Simon Bailey et al.	Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A2	2008
Professor David Ellison Professor Steven Clifford	Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features	2008
Professor Steven Clifford Dr Meryl Lusher Dr Janet Lindsey Dr Jackie Langdon Dr Richard Gilbertson et al.	Wnt-pathway medulloblastomas	2008
Professor David Ellison Dr Janet Lindsey Dr Meryl Lusher Professor Steven Clifford	Beta-catenin status predicts favorable prognosis in childhood medulloblastoma	2007
Professor Steven Clifford Yuan Lu Dr Debbie Scott Professor David Ellison	Chromosome 8 contains multiple independent loci involved in medulloblastoma development	2007
Professor David Ellison Dr Richard Gilbertson	Clinical and molecular characteristics of malignant transformation of low-grade glioma in children	2007
Dr Janet Lindsey Dr Meryl Lusher Jennifer Anderton Dr Richard Gilbertson Professor David Ellison et al.	Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma	2007
Professor Steven Clifford Professor David Ellison	Identification of novel mechanisms for gene disruption at the medulloblastoma isochromosome breakpoint locus	2007
Charles McManamy Dr Jane Pears Professor Steven Clifford Professor David Ellison	Nodule formation and desmoplasia in medulloblastomas - Defining the nodular/desmoplastic variant and its biological behavior	2007
Professor David Ellison	Presence of factors predictive of response to anti-EGFR therapy in pediatric high-grade gliomas	2007
Professor David Ellison	Primary postoperative chemotherapy without radiotherapy for intracranial ependymoma in children: the UKCCSG/SIOP prospective study	2007
Professor David Ellison Beth Gibson Dr Pamela Kearns	The childhood tumour and leukaemia banks - A national protocol for collecting and banking childhood cancer tissue samples for research - On behalf of the CCLG Biological Studies Steering Group	2007
Professor David Ellison	Trisomy 19 ependymoma, a newly recognized genetico-histological association, including clear cell ependymoma	2007
Dr Vankateswara Ramesh Dr Anil Gholkar OBE Professor David Ellison	Alexander disease - Ventricular garlands and abnormalities of the medulla and spinal cord	2006
Olabisi Onilude Dr Meryl Lusher Dr Janet Lindsey Professor Andrew Pearson Professor David Ellison et al.	APC and CTNNB1 mutations are rare in sporadic ependymomas	2006
Professor David Ellison Emeritus Professor David Mendelow	Cathepsin S expression: An independent prognostic factor in glioblastoma tumours - A pilot study	2006
Dr Jackie Langdon Dr Jayne Lamont Dr Debbie Scott Dr Nicholas Bown Professor David Ellison et al.	Combined genome-wide allelotyping and copy number analysis identify frequent genetic losses without copy number reduction in medulloblastoma	2006
Dr Janet Lindsey Dr Meryl Lusher Dr Gordon Strathdee Robert Brown Dr Richard Gilbertson et al.	Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours	2006
Dr Janet Lindsey Dr Meryl Lusher Dr Gordon Strathdee Dr Richard Gilbertson Professor Simon Bailey et al.	Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours	2006
Dr Debbie Scott Debbie Straughton Mike Cole Professor Simon Bailey Professor David Ellison et al.	Identification and analysis of tumor suppressor loci at chromosome 10q23.3-10q25.3 in medulloblastoma	2006
Professor David Ellison	Identification of candidate tumor-suppressor genes on chromosome 8p in medulloblastomas by expression profiling	2006
Professor Steven Clifford Dr Meryl Lusher Dr Janet Lindsey Dr Jackie Langdon Dr Richard Gilbertson et al.	Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis	2006
Professor David Ellison Olabisi Onilude Dr Janet Lindsey Dr Meryl Lusher Professor Andrew Pearson et al.	β-catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour Committee	2005
Dr Jayne Lamont Professor Deborah Tweddle Professor Andrew Pearson Professor Steven Clifford Professor David Ellison et al.	A 7-year-old boy with midline cerebellar mass	2005
Professor David Ellison Dr Timothy Williams	A beta-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy	2005
David Hamilton Dr Meryl Lusher Dr Janet Lindsey Professor David Ellison Professor Steven Clifford et al.	Epigenetic inactivation of the RASSF1A tumour suppressor gene in ependymoma	2005
Professor David Ellison	Outcome for patients with metastatic (M2-3) medulloblastoma treated with SIOP/UKCCSG PNET-3 chemotherapy	2005
Patrick Mitchell Professor David Ellison Emeritus Professor David Mendelow	Surgery for malignant gliomas: mechanistic reasoning and slippery statistics	2005
Professor David Ellison	Woman aged 24 years with fourth ventricular mass	2005
Helen Fernandes Professor David Ellison	Woman aged 24 years with fourth ventricular mass	2005
Professor David Ellison Professor Andrew Pearson Professor Steven Clifford Dr Jayne Lamont Charles McManamy et al.	Combined histopathological and molecular cytogenetic stratification defines a high-risk subset of patients with medulloblastoma - A United Kingdom Children's Cancer Group Study	2004
Dr Jayne Lamont Charles McManamy Professor Andrew Pearson Professor Steven Clifford Professor David Ellison et al.	Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients	2004
Professor David Ellison	Genetic and expression profiles of cerebellar liponeurocytomas	2004
Professor David Ellison	Genomic imbalances in high- and low-grade paediatric astrocytomas	2004
Professor David Ellison	Genomic imbalances in supratentorial primitive neuroectodermal tumours (stPNETS)	2004
Professor Steven Clifford Dr Janet Lindsey Dr Meryl Lusher Dr Richard Gilbertson Professor Andrew Pearson et al.	Identification of tumour suppressor genes in childhood medulloblastoma by promoter hypermethylation profiling	2004
Dr Janet Lindsey Dr Meryl Lusher Jennifer Anderton Professor Simon Bailey Dr Richard Gilbertson et al.	Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling	2004
Professor David Ellison Dr Helen Lucraft Dr Richard Gilbertson	Impact of radiotherapy parameters on outcome in the International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 study of preradiotherapy chemotherapy for M0-M1 medulloblastoma	2004
Professor David Ellison Charles McManamy Professor Andrew Pearson Professor Steven Clifford	The clinical utility of stratifying medulloblastomas (MBs) by a combination of detailed histopathologic evaluation and molecular cytogenetic analysis	2004
Dr Janet Lindsey Dr Meryl Lusher Professor Andrew Pearson Professor David Ellison Professor Steven Clifford et al.	Identification of tumour suppressor genes in childhood medulloblastoma by promoter hypermethylation profiling	2003
Dr Debbie Scott Dr Janet Lindsey Dr Meryl Lusher Professor Andrew Pearson Professor David Ellison et al.	Identification of tumour suppressor loci on chromosome 10q in medulloblastoma	2003
Dr Jayne Lamont Charles McManamy Professor Andrew Pearson Professor Steven Clifford Professor David Ellison et al.	Molecular cytogenetic analysis of a cohort of medulloblastomas	2003
Charles McManamy Dr Jayne Lamont Mike Cole Professor Andrew Pearson Professor Steven Clifford et al.	Morphophenotypic variation predicts clinical behavior in childhood non-desmoplastic medulloblastomas	2003
Professor David Ellison Dr Helen Lucraft Dr Richard Gilbertson	Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: The International Society of Paediatric Oncology United Kingdom Children's Cancer Study Group PNET-3 study	2003
Professor David Ellison Dr Daniel Birchall	Use of serial proton magnetic resonance spectroscopy to differentiate low grade glioma from tumefactive plaque in a patient with multiple sclerosis	2003
Professor David Ellison Professor Steven Clifford Dr Richard Gilbertson	What's new in neuro-oncology? Recent advances in medulloblastoma	2003
Dr Meryl Lusher Dr Janet Lindsey Professor Andrew Pearson Professor David Ellison Professor Steven Clifford et al.	Biallelic epigenetic inactivation of the RASSF1A tumor suppressor gene in medulloblastoma development	2002
Professor David Ellison	Classifying the medulloblastoma: insights from morphology and molecular genetics	2002
Dr Richard Gilbertson Roberto Hernan Dr Adrian Frank Professor David Ellison	ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease	2002
Emeritus Professor Robert Perry Dr David Walker Dr Richard Gilbertson Professor David Ellison	Genetic abnormalities detected in ependymomas by comparative genomic hybridisation	2002
Emeritus Professor Robert Perry Professor David Ellison	Genetic abnormalities detected in genomic hybridisation epenclymomas by comparative	2002
Professor David Ellison	Genomic imbalances in pediatric intracranial ependymomas define clinically relevant groups	2002
Dr Richard Gilbertson Roberto Hernan Emeritus Professor Robert Perry Professor John Lunec Professor Andrew Pearson et al.	Clinical and molecular stratification of disease risk in medulloblastoma	2001
Professor David Ellison	Genomic imbalances in paediatric ependymomas; A United Kingdom Childrens Cancer Study Group (UKCCSG) approved study	2001
Professor David Ellison	Genomic imbalances in paediatric ependymomas; A United Kingdom Children's Cancer Study Group (UKCCSG) approved study	2001
Professor David Ellison Dr Bridget Wilkins	Lymphoma and the nervous system	2001
Dr Richard Gilbertson Professor David Ellison	Molecular stratification of disease risk in childhood medulloblastoma	2001
Dr Richard Gilbertson Roberto Hernan Professor David Ellison Emeritus Professor Robert Perry Professor Andrew Pearson et al.	Novel ErbB4 juxtamembrane splice variants and the truncated ErbB2 receptor isoform are frequently expressed in childhood medulloblastoma	2001
Dr Richard Gilbertson Roberto Hernan Professor David Ellison Emeritus Professor Robert Perry Professor Andrew Pearson et al.	Novel ERBB4 juxtamembrane splice variants are frequently expressed in childhood medulloblastoma	2001
Dr David Walker Professor David Ellison	Analysis of ependymomas using comparative genomic hybridisation	2000
Professor David Ellison	Comparative genomic hybridization and histological variation in primitive neuroectodermal tumours	1999
Professor David Ellison	V-H gene sequences from primary central nervous system lymphomas indicate derivation from highly mutated germinal cancer B cells with ongoing mutational activity	1999
Professor David Ellison Professor John Lunec Dr Evelyn Jaros	Accumulation of wild-type p53 in meningiomas	1995