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Plasticity of rodent and human hair follicle dermal cells: Implications for cell therapy and tissue engineering

Lookup NU author(s): Dr Gavin RichardsonORCiD, Dr Clifford Lawrence, Dr Nicholas Hole, Professor Colin Jahoda


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The dermal components of the hair follicle exhibit a number of stem cell properties, including regenerative potential, roles in wound healing and the ability to produce a functional dermis. Here we examine the stem cell phenomenon of plasticity, focusing on recent observations of in vitro plasticity of dermal papilla and sheath cells, including previously unpublished data of neuronal-like differentiation. We then briefly address the implications of the stem cell potential of hair follicle dermal cells for the field of tissue engineering.

Publication metadata

Author(s): Richardson GD, Arnott EC, Whitehouse CJ, Lawrence CM, Reynolds AJ, Hole N, Jahoda CAB

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: Journal of Investigative Dermatology Symposium Proceedings: 4th International Meeting of Hair Research Societies

Year of Conference: 2005

Pages: 180-183

ISSN: 1087-0024

Publisher: Nature Publishing Group


DOI: 10.1111/j.1087-0024.2005.10101.x

Library holdings: Search Newcastle University Library for this item

ISBN: 15291774