Publications by Professor Gavin Richardson - ePrints

Browsing publications by Professor Gavin Richardson.

Newcastle Authors	Title	Year
Yasemin Ekinci Professor Gavin Richardson Professor Ioakim Spyridopoulos	A Phase IIa Clinical Trial of KAND567, Fractalkine Receptor Inhibitor, in Patients with ST-Elevation Acute Myocardial Infarction after Percutaneous Coronary Intervention	2024
Dr Maria Camacho Encina Laura Booth Dr Rachael Redgrave Dr Omowumi Folaranmi Professor Ioakim Spyridopoulos et al.	Cellular Senescence, Mitochondrial Dysfunction, and Their Link to Cardiovascular Disease	2024
Dr Annette Meeson Dr Rachel Oldershaw Professor Gavin Richardson	Differentiation, metabolism and cardioprotective secretory functions of human cardiac stromal cells from ischemic and endocarditis patients	2024
Dr Maria Camacho Encina Laura Booth Dr Rachael Redgrave Minna Honkanen-Scott Dr Bill Scott et al.	Identifying optimal reference genes for real-time quantitative polymerase chain reaction in human myocardial tissues	2024
Professor Gavin Richardson	Multimorbidity is associated with myocardial DNA damage, nucleolar stress, dysregulated energy metabolism, and senescence in cardiovascular disease	2024
George Kelly Dr Tetsushi Kataura Dr Johan Panek Hanna Salmonowicz Hannah Kendall et al.	Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule	2024
Dr Rachael Redgrave Dr Anna Walaszczyk Micheylla Dewi Dr Maria Camacho Encina Professor Gavin Richardson et al.	The effect of varying irrigation flow-rate during irrigated radiofrequency ablation on optimising lesion shape	2024
Dr Bilal Bawamia Dr Luke Spray Vincent Wangsaputra Dr Karim Bennaceur Dr Sharareh Vahabi et al.	Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction Randomized Pilot Trial	2023
Dr Kateryna Sopova Dr Simon Tual-Chalot Dr Nikolaos Vlachogiannis Dr Georgios Georgiopoulos Dr Luke Spray et al.	Effector T cell chemokine IP-10 predicts cardiac recovery and clinical outcomes post-myocardial infarction	2023
Shu Xian Loh Yasemin Ekinci Dr Luke Spray Dr Visvesh Jeyalan Professor Gavin Richardson et al.	Fractalkine Signalling (CX₃CL1/CX₃CR1 Axis) as an Emerging Target in Coronary Artery Disease.	2023
Laura Booth Dr Rachael Redgrave Dr Simon Tual-Chalot Professor Ioakim Spyridopoulos Dr Helen Phillips et al.	Heart Disease and Ageing: The Roles of Senescence, Mitochondria, and Telomerase in Cardiovascular Disease	2023
Dr Maria Camacho Encina Dr Rachael Redgrave Professor Gavin Richardson	Identifying older donor hearts suitable for transplantation: the use of senescence as a marker of biological age	2023
Professor Miles Witham Dr Antoneta Granic Dr Satomi Miwa Professor Gavin Richardson Professor Avan Sayer et al.	New Horizons in cellular senescence for clinicians	2023
Dr Rachael Redgrave Dr Emily Dookun Laura Booth Dr Maria Camacho Encina Dr Omowumi Folaranmi et al.	Senescent cardiomyocytes contribute to cardiac dysfunction following myocardial infarction	2023
Dr Rachael Redgrave Dr Maria Camacho Encina Dr Simon Tual-Chalot Dr Omowumi Folaranmi Dr Carmen Martin-Ruiz et al.	The senescence-associated secretory phenotype as a biomarker for age-related myocardial remodelling and cardiovascular disease	2023
Professor Ioakim Spyridopoulos Dr Bilal Bawamia Dr Luke Spray Vincent Wangsaputra Professor Konstantinos Stellos et al.	Activation of mitochondrial telomerase reverses relative lymphopenia post myocardial infarction: results from the randomised, double-blinded TACTIC phase IIa pilot trial	2022
Laura Booth Dr Rachael Redgrave Dr Omowumi Folaranmi Professor Gavin Richardson	Anthracycline-induced cardiotoxicity and senescence	2022
Rachel Oldershaw Professor Gavin Richardson Pip Carling Dr Andrew Owens Dr Annette Meeson et al.	Cardiac Mesenchymal Stem Cell-like Cells Derived from a Young Patient with Bicuspid Aortic Valve Disease Have a Prematurely Aged Phenotype	2022
Dr Anna Walaszczyk Dr Emily Dookun Dr Rachael Redgrave Dr Pawel Palmowski Dr Simon Tual-Chalot et al.	Therapeutic potential of navitoclax in age-related cardiovascular diseases	2022
Emily Dookun Dr Joao Passos Professor Helen Arthur Professor Gavin Richardson	Therapeutic Potential of Senolytics in Cardiovascular Disease	2022
Jose Coelho Lima Junior Dr Georgios Georgiopoulos Dr Jannath Ahmed David Gaskin Dr Konstantinos Bakogiannis et al.	Prognostic value of admission high-sensitivity troponin in patients with ST-elevation myocardial infarction	2021
Dr Andrew Owens Dr Anna Walaszczyk Professor Ioakim Spyridopoulos Dr Emily Dookun Professor Gavin Richardson et al.	Senescence and Senolytics in Cardiovascular disease: Promise and Potential Pitfalls	2021
Jedrzej Hoffmann Professor Gavin Richardson Professor Ioakim Spyridopoulos	Telomerase As a Therapeutic Target in Cardiovascular Disease	2021
Dr Luke Spray Dr Catherine Park Dr Suzanne Cormack Dr Ashfaq Mohammed Dr Stephen Boag et al.	The Fractalkine Receptor CX3CR1 Links Lymphocyte Kinetics in CMV-Seropositive Patients and Acute Myocardial Infarction With Adverse Left Ventricular Remodeling	2021
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Pawel Palmowski Dr Simon Tual-Chalot et al.	Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery	2020
Dr Carmen Martin-Ruiz Professor Thomas von Zglinicki Professor Gavin Richardson Lilia Draganova Dr Rachael Redgrave et al.	CMV-independent increase in CD27−CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians	2020
Danlin Liu Professor Gavin Richardson Dr Fehmi Benli Dr Catherine Park Joao Victor de De Souza Cunha et al.	Inflammageing in the cardiovascular system: mechanisms, emerging targets, and novel therapeutic strategies	2020
Dr Catherine Park Dr Suzanne Cormack Dr Stephen Boag Dr Karim Bennaceur Professor Gavin Richardson et al.	Role of CMV-serostatus and CX3CR1 on lymphocyte kinetics and left ventricular remodelling in patients with acute myocardial infarction	2020
Micheylla Dewi Dr Anna Walaszczyk Professor Gavin Richardson	Continuous Reduction In Irrigation Rate During Irrigated Radiofrequency Catheter Ablation Results In A More Optimised Lesion Shape Through Reduced Endocardial Sparing	2019
Dr Rachel Oldershaw Dr Andrew Owens Rachel Telfer-Sutherland Martin Linney Rachel Liddle et al.	Human Cardiac-Mesenchymal Stem Cell-Like Cells, a Novel Cell Population with Therapeutic Potential	2019
Rhys Anderson Anthony Lagnado Damien Maggiorani Dr Anna Walaszczyk Emily Dookun et al.	Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence	2019
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot Oliver Yausep et al.	Navitoclax eliminates senescence attenuating remodelling and improving outcome to cardiac ischemia-reperfusion injury	2019
Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Dr Simon Tual-Chalot Professor Ioakim Spyridopoulos et al.	Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction.	2019
Clara Correia Melo Dr Jodie Birch Dr Edward Fielder Dr James Chapman Dr Anthony Lagnado et al.	Rapamycin improves healthspan but not inflammaging in nfkb1-/- mice	2019
Oliver Yausep Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot et al.	The Effects of Senolytics on Murine Cardiac Function and Morphology Post-Ischemia Reperfusion Injury	2019
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot Oliver Yausep et al.	Accumulation of cardiomyocyte senescence following ischaemia-reperfusion injury (IRI); a potential therapeutic target?	2018
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot Oliver Yausep et al.	Cardiomyocyte Senescence accumulates following Myocardial Infarction and Ischaemia-Reperfusion Injury.	2018
Rhys Anderson Professor Gavin Richardson Dr Joao Passos	Mechanisms driving the ageing heart	2018
Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Dr Simon Tual-Chalot Rhys Anderson et al.	Senescence as a therapeutic target for myocardial ageing	2018
Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Professor Ioakim Spyridopoulos Professor Helen Arthur et al.	Senescence contributes age related cardiac dysfunction	2018
Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Professor Ioakim Spyridopoulos Professor Helen Arthur et al.	Senescence contributes to reduced survival and impaired cardiac function following myocardial infraction in aged mice.	2018
Professor Gavin Richardson Dr Karim Bennaceur Emily Dookun Lilia Draganova Dr Gabriele Saretzki et al.	Telomerase Mediates Lymphocyte Proliferation but Not the Atherosclerosis-Suppressive Potential of Regulatory T-Cells	2018
Damien Maggiorani Professor Gavin Richardson Dr Joao Passos	Young vs Old mouse cardiomyocytes RNA-Seq.	2018
Kimberly Rockley Professor Gavin Richardson Dr Jason Gill	Characterisation of novel molecular mechanisms involved in anthracycline-induced cardiotoxicity	2016
Professor Gavin Richardson Professor Colin Jahoda	Contribution of GFP expressing Dermal Papillae cells to the formation of chimeric embryos and their survival in uterine environment.	2016
Professor Gavin Richardson	Simultaneous Assessment of Cardiomyocyte DNA Synthesis and Ploidy: A Method to Assist Quantification of Cardiomyocyte Regeneration and Turnover	2016
Professor Bob Anderson Dr Simon Tual-Chalot Dr Rachael Redgrave Rebecca Dodds Dr Andrew Owens et al.	The role of cardiomyocyte senescence and regeneration in Ageing	2016
Professor Gavin Richardson Dr Steven Laval Dr Andrew Owens	Cardiomyocyte regeneration in the mdx mouse model of non-ischemic cardiomyopathy	2015
Dr Karim Bennaceur Mark Atwill Nayef Al Zhrany Jedrzej Hoffmann Professor Bernard Keavney et al.	Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism	2014
Dr Andrew Owens Professor Gavin Richardson	Cardiomyocyte regeneration in non-ischaemic cardiomyopathy	2014
Dr Annette Meeson Andrew Fuller Dr Andrew Owens Professor Gavin Richardson	Optimised Protocols for the Identification of the Murine Cardiac Side Population	2013
Dr Annette Meeson Dr Steven Laval Dr Andrew Owens Professor Gavin Richardson	The Cardiac Side Population is Dynamic during the Progression of Cardiomyopathy in the mdx Model of DMD	2013
Professor Gavin Richardson Dr Annette Meeson Dr Steven Laval Andrew Fuller Dr Andrew Owens et al.	mTert Expression is Increased in the mdx Model of Cardiomyopathy	2012
Dr Emma Bell Professor Gavin Richardson Professor Colin Jahoda Dr Helen Phillips Professor Deborah Henderson et al.	Dermal stem cells can differentiate down an endothelial lineage	2012
Professor Gavin Richardson Dr Annette Meeson Dr Steven Laval Dr Andrew Owens	mTert Expression is Increased in the MDX Model of Cardiomyopathy	2012
Craig Higgins Professor Gavin Richardson Professor Colin Jahoda	Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells	2012
Professor Gavin Richardson Dr Suzanne Cormack Dr Andrew Owens	Telomerase expression in the mammalian heart	2012
Professor Gavin Richardson Professor Colin Jahoda	Modelling the hair follicle dermal papilla using spheroid cell cultures	2010
Professor Gavin Richardson Dr Nicholas Hole Dr Andrew Owens	The Identification of Native Cardiac Stem Cells Based on Telomerase Activity	2010
Professor Gavin Richardson	Dynamic expression of Syndecan-1 during hair follicle morphogenesis	2009
Professor Gavin Richardson	Exogen involves gradual release of the hair club fibre in the vibrissa follicle model	2009
Professor Gavin Richardson	Keratin 10 (K10) is expressed suprabasally throughout the limbus of embryonic and neonatal rat corneas, with interrupted expression in the adult limbus.	2009
Professor Gavin Richardson	KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin	2009
Professor Gavin Richardson	Multiple Properties of Hair Follicle Dermis Include Stem Cell Potential, Stem Cell Support, and Epithelial Reprogramming	2009
Professor Gavin Richardson	Activation of EGF and FGF signaling in developing mouse skin inhibits hair follicle morphogenesis	2007
Professor Gavin Richardson Dr Amy Fearn Professor Colin Jahoda	Hair and skin differentiation from the transit amplifying cells of the central cornea	2007
Professor Gavin Richardson	Hair follicle stem cells	2007
Dr Amy Fearn Professor Gavin Richardson Professor Colin Jahoda	Stem and developmental potential of the hair follicle – induction, regeneration, wound healing and stem cells	2007
Professor Gavin Richardson	The Wnt inhibitor, Dickkopf 4, is induced by canonical Wnt signaling during ectodermal appendage morphogenesis	2007
Professor Gavin Richardson	Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression	2007
Professor Gavin Richardson	Determining the molecular basis of hair follicle induction.	2006
Professor Gavin Richardson	Analysing the mechanisms of follicle dermal cell aggregation and induction: a cell and molecular study	2005
Professor Gavin Richardson Dr Clifford Lawrence Dr Nicholas Hole Professor Colin Jahoda	Cultured cells from the adult human hair follicle dermis can be directed toward adipogenic and osteogenic differentiation.	2005
Professor Gavin Richardson Dr Clifford Lawrence Dr Nicholas Hole Professor Colin Jahoda	Plasticity of rodent and human hair follicle dermal cells: Implications for cell therapy and tissue engineering	2005
Professor Gavin Richardson Professor Craig Robson Professor David Neal Dr Anne Collins	CD133, a novel marker for human prostatic epithelial stem cells	2004
Professor Gavin Richardson Dr Nicholas Hole	Stem cell potential of adult hair follicle dermal cells	2004