Yasemin Ekinci Professor Gavin Richardson Professor Ioakim Spyridopoulos
| A Phase IIa Clinical Trial of KAND567, Fractalkine Receptor Inhibitor, in Patients with ST-Elevation Acute Myocardial Infarction after Percutaneous Coronary Intervention | 2024 |
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Dr Maria Camacho Encina Laura Booth Dr Rachael Redgrave Dr Omowumi Folaranmi Professor Ioakim Spyridopoulos et al. | Cellular Senescence, Mitochondrial Dysfunction, and Their Link to Cardiovascular Disease | 2024 |
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Dr Annette Meeson Dr Rachel Oldershaw Professor Gavin Richardson
| Differentiation, metabolism and cardioprotective secretory functions of human cardiac stromal cells from ischemic and endocarditis patients | 2024 |
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George Kelly Dr Tetsushi Kataura Dr Johan Panek Hanna Salmonowicz Hannah Kendall et al. | Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule | 2024 |
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Dr Rachael Redgrave Dr Anna Walaszczyk Micheylla Dewi Dr Maria Camacho Encina Professor Gavin Richardson et al. | The effect of varying irrigation flow-rate during irrigated radiofrequency ablation on optimising lesion shape | 2024 |
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Dr Bilal Bawamia Dr Luke Spray Vincent Wangsaputra Dr Karim Bennaceur Dr Sharareh Vahabi et al. | Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction Randomized Pilot Trial | 2023 |
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Dr Kateryna Sopova Dr Simon Tual-Chalot Dr Nikolaos Vlachogiannis Dr Georgios Georgiopoulos Dr Luke Spray et al. | Effector T cell chemokine IP-10 predicts cardiac recovery and clinical outcomes post-myocardial infarction | 2023 |
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Shu Xian Loh Yasemin Ekinci Dr Luke Spray Dr Visvesh Jeyalan Professor Gavin Richardson et al. | Fractalkine Signalling (CX3CL1/CX3CR1 Axis) as an Emerging Target in Coronary Artery Disease. | 2023 |
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Laura Booth Dr Rachael Redgrave Dr Simon Tual-Chalot Professor Ioakim Spyridopoulos Dr Helen Phillips et al. | Heart Disease and Ageing: The Roles of Senescence, Mitochondria, and Telomerase in Cardiovascular Disease | 2023 |
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Dr Maria Camacho Encina Dr Rachael Redgrave Professor Gavin Richardson
| Identifying older donor hearts suitable for transplantation: the use of senescence as a marker of biological age | 2023 |
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Professor Miles Witham Dr Antoneta Granic Dr Satomi Miwa Professor Gavin Richardson Professor Avan Sayer et al. | New Horizons in cellular senescence for clinicians | 2023 |
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Dr Rachael Redgrave Dr Emily Dookun Laura Booth Dr Maria Camacho Encina Dr Omowumi Folaranmi et al. | Senescent cardiomyocytes contribute to cardiac dysfunction following myocardial infarction | 2023 |
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Dr Rachael Redgrave Dr Maria Camacho Encina Dr Simon Tual-Chalot Dr Omowumi Folaranmi Dr Carmen Martin-Ruiz et al. | The senescence-associated secretory phenotype as a biomarker for age-related myocardial remodelling and cardiovascular disease | 2023 |
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Professor Ioakim Spyridopoulos Dr Bilal Bawamia Dr Luke Spray Vincent Wangsaputra Professor Konstantinos Stellos et al. | Activation of mitochondrial telomerase reverses relative lymphopenia post myocardial infarction: results from the randomised, double-blinded TACTIC phase IIa pilot trial | 2022 |
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Laura Booth Dr Rachael Redgrave Dr Omowumi Folaranmi Professor Gavin Richardson
| Anthracycline-induced cardiotoxicity and senescence | 2022 |
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Rachel Oldershaw Professor Gavin Richardson Pip Carling Dr Andrew Owens Dr Annette Meeson et al. | Cardiac Mesenchymal Stem Cell-like Cells Derived from a Young Patient with Bicuspid Aortic Valve Disease Have a Prematurely Aged Phenotype | 2022 |
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Dr Anna Walaszczyk Dr Emily Dookun Dr Rachael Redgrave Dr Pawel Palmowski Dr Simon Tual-Chalot et al. | Therapeutic potential of navitoclax in age-related cardiovascular diseases | 2022 |
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Emily Dookun Dr Joao Passos Professor Helen Arthur Professor Gavin Richardson
| Therapeutic Potential of Senolytics in Cardiovascular Disease | 2022 |
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Jose Coelho Lima Junior Dr Georgios Georgiopoulos Dr Jannath Ahmed David Gaskin Dr Konstantinos Bakogiannis et al. | Prognostic value of admission high-sensitivity troponin in patients with ST-elevation myocardial infarction | 2021 |
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Dr Andrew Owens Dr Anna Walaszczyk Professor Ioakim Spyridopoulos Dr Emily Dookun Professor Gavin Richardson et al. | Senescence and Senolytics in Cardiovascular disease: Promise and Potential Pitfalls | 2021 |
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Jedrzej Hoffmann Professor Gavin Richardson Professor Ioakim Spyridopoulos
| Telomerase As a Therapeutic Target in Cardiovascular Disease | 2021 |
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Dr Catherine Park Dr Suzanne Cormack Dr Ashfaq Mohammed Dr Stephen Boag Dr Karim Bennaceur et al. | The Fractalkine Receptor CX3CR1 Links Lymphocyte Kinetics in CMV-Seropositive Patients and Acute Myocardial Infarction With Adverse Left Ventricular Remodeling | 2021 |
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Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Pawel Palmowski Dr Simon Tual-Chalot et al. | Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery | 2020 |
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Dr Carmen Martin-Ruiz Professor Thomas von Zglinicki Professor Gavin Richardson Lilia Draganova Dr Rachael Redgrave et al. | CMV-independent increase in CD27−CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians | 2020 |
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Danlin Liu Professor Gavin Richardson Fehmi Benli Dr Catherine Park Joao Victor de De Souza Cunha et al. | Inflammageing in the cardiovascular system: mechanisms, emerging targets, and novel therapeutic strategies | 2020 |
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Dr Catherine Park Dr Suzanne Cormack Dr Stephen Boag Dr Karim Bennaceur Professor Gavin Richardson et al. | Role of CMV-serostatus and CX3CR1 on lymphocyte kinetics and left ventricular remodelling in patients with acute myocardial infarction | 2020 |
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Micheylla Dewi Dr Anna Walaszczyk Professor Gavin Richardson
| Continuous Reduction In Irrigation Rate During Irrigated Radiofrequency Catheter Ablation Results In A More Optimised Lesion Shape Through Reduced Endocardial Sparing | 2019 |
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Dr Rachel Oldershaw Dr Andrew Owens Rachel Telfer-Sutherland Martin Linney Rachel Liddle et al. | Human Cardiac-Mesenchymal Stem Cell-Like Cells, a Novel Cell Population with Therapeutic Potential | 2019 |
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Rhys Anderson Anthony Lagnado Damien Maggiorani Dr Anna Walaszczyk Emily Dookun et al. | Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence | 2019 |
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Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot Oliver Yausep et al. | Navitoclax eliminates senescence attenuating remodelling and improving outcome to cardiac ischemia-reperfusion injury | 2019 |
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Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Dr Simon Tual-Chalot Professor Ioakim Spyridopoulos et al. | Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction. | 2019 |
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Clara Correia Melo Dr Jodie Birch Dr Ed Fielder Dr James Chapman Dr Anthony Lagnado et al. | Rapamycin improves healthspan but not inflammaging in nfkb1-/- mice | 2019 |
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Oliver Yausep Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot et al. | The Effects of Senolytics on Murine Cardiac Function and Morphology Post-Ischemia Reperfusion Injury | 2019 |
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Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot Oliver Yausep et al. | Accumulation of cardiomyocyte senescence following ischaemia-reperfusion injury (IRI); a potential therapeutic target? | 2018 |
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Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot Oliver Yausep et al. | Cardiomyocyte Senescence accumulates following Myocardial Infarction and Ischaemia-Reperfusion Injury. | 2018 |
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Rhys Anderson Professor Gavin Richardson Dr Joao Passos
| Mechanisms driving the ageing heart | 2018 |
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Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Dr Simon Tual-Chalot Rhys Anderson et al. | Senescence as a therapeutic target for myocardial ageing | 2018 |
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Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Professor Ioakim Spyridopoulos Professor Helen Arthur et al. | Senescence contributes age related cardiac dysfunction | 2018 |
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Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Professor Ioakim Spyridopoulos Professor Helen Arthur et al. | Senescence contributes to reduced survival and impaired cardiac function following myocardial infraction in aged mice. | 2018 |
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Professor Gavin Richardson Dr Karim Bennaceur Emily Dookun Lilia Draganova Dr Gabriele Saretzki et al. | Telomerase Mediates Lymphocyte Proliferation but Not the Atherosclerosis-Suppressive Potential of Regulatory T-Cells | 2018 |
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Damien Maggiorani Professor Gavin Richardson Dr Joao Passos
| Young vs Old mouse cardiomyocytes RNA-Seq. | 2018 |
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Kimberly Rockley Professor Gavin Richardson Dr Jason Gill
| Characterisation of novel molecular mechanisms involved in anthracycline-induced cardiotoxicity | 2016 |
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Professor Gavin Richardson Professor Colin Jahoda
| Contribution of GFP expressing Dermal Papillae cells to the formation of chimeric embryos and their survival in uterine environment. | 2016 |
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Professor Gavin Richardson
| Simultaneous Assessment of Cardiomyocyte DNA Synthesis and Ploidy: A Method to Assist Quantification of Cardiomyocyte Regeneration and Turnover | 2016 |
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Professor Bob Anderson Dr Simon Tual-Chalot Dr Rachael Redgrave Rebecca Dodds Dr Andrew Owens et al. | The role of cardiomyocyte senescence and regeneration in Ageing | 2016 |
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Professor Gavin Richardson Dr Steven Laval Dr Andrew Owens
| Cardiomyocyte regeneration in the mdx mouse model of non-ischemic cardiomyopathy | 2015 |
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Dr Karim Bennaceur Mark Atwill Nayef Al Zhrany Jedrzej Hoffmann Professor Bernard Keavney et al. | Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism | 2014 |
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Dr Andrew Owens Professor Gavin Richardson
| Cardiomyocyte regeneration in non-ischaemic cardiomyopathy | 2014 |
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Dr Annette Meeson Andrew Fuller Dr Andrew Owens Professor Gavin Richardson
| Optimised Protocols for the Identification of the Murine Cardiac Side Population | 2013 |
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Dr Annette Meeson Dr Steven Laval Dr Andrew Owens Professor Gavin Richardson
| The Cardiac Side Population is Dynamic during the Progression of Cardiomyopathy in the mdx Model of DMD | 2013 |
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Professor Gavin Richardson Dr Annette Meeson Dr Steven Laval Andrew Fuller Dr Andrew Owens et al. | mTert Expression is Increased in the mdx Model of Cardiomyopathy | 2012 |
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Dr Emma Bell Professor Gavin Richardson Professor Colin Jahoda Dr Helen Phillips Professor Deborah Henderson et al. | Dermal stem cells can differentiate down an endothelial lineage | 2012 |
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Professor Gavin Richardson Dr Annette Meeson Dr Steven Laval Dr Andrew Owens
| mTert Expression is Increased in the MDX Model of Cardiomyopathy | 2012 |
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Craig Higgins Professor Gavin Richardson Professor Colin Jahoda
| Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells | 2012 |
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Professor Gavin Richardson Dr Suzanne Cormack Dr Andrew Owens
| Telomerase expression in the mammalian heart | 2012 |
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Professor Gavin Richardson Professor Colin Jahoda
| Modelling the hair follicle dermal papilla using spheroid cell cultures | 2010 |
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Professor Gavin Richardson Dr Nicholas Hole Dr Andrew Owens
| The Identification of Native Cardiac Stem Cells Based on Telomerase Activity | 2010 |
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Professor Gavin Richardson
| Dynamic expression of Syndecan-1 during hair follicle morphogenesis | 2009 |
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Professor Gavin Richardson
| Exogen involves gradual release of the hair club fibre in the vibrissa follicle model | 2009 |
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Professor Gavin Richardson
| Keratin 10 (K10) is expressed suprabasally throughout the limbus of embryonic and neonatal rat corneas, with interrupted expression in the adult limbus. | 2009 |
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Professor Gavin Richardson
| KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin | 2009 |
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Professor Gavin Richardson
| Multiple Properties of Hair Follicle Dermis Include Stem Cell Potential, Stem Cell Support, and Epithelial Reprogramming | 2009 |
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Professor Gavin Richardson
| Activation of EGF and FGF signaling in developing mouse skin inhibits hair follicle morphogenesis | 2007 |
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Professor Gavin Richardson Dr Amy Fearn Professor Colin Jahoda
| Hair and skin differentiation from the transit amplifying cells of the central cornea | 2007 |
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Professor Gavin Richardson
| Hair follicle stem cells | 2007 |
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Dr Amy Fearn Professor Gavin Richardson Professor Colin Jahoda
| Stem and developmental potential of the hair follicle – induction, regeneration, wound healing and stem cells | 2007 |
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Professor Gavin Richardson
| The Wnt inhibitor, Dickkopf 4, is induced by canonical Wnt signaling during ectodermal appendage morphogenesis | 2007 |
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Professor Gavin Richardson
| Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression | 2007 |
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Professor Gavin Richardson
| Determining the molecular basis of hair follicle induction. | 2006 |
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Professor Gavin Richardson
| Analysing the mechanisms of follicle dermal cell aggregation and induction: a cell and molecular study | 2005 |
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Professor Gavin Richardson Dr Clifford Lawrence Dr Nicholas Hole Professor Colin Jahoda
| Cultured cells from the adult human hair follicle dermis can be directed toward adipogenic and osteogenic differentiation. | 2005 |
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Professor Gavin Richardson Dr Clifford Lawrence Dr Nicholas Hole Professor Colin Jahoda
| Plasticity of rodent and human hair follicle dermal cells: Implications for cell therapy and tissue engineering | 2005 |
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Professor Gavin Richardson Professor Craig Robson Professor David Neal Dr Anne Collins
| CD133, a novel marker for human prostatic epithelial stem cells | 2004 |
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Professor Gavin Richardson Dr Nicholas Hole
| Stem cell potential of adult hair follicle dermal cells | 2004 |
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