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Postponement of postmenopausal mortality acceleration in low-mortality populations

Lookup NU author(s): Emeritus Professor Eugene Milne


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Mortality analyses commonly disregard postmenopausal acceleration. This study examined period log mortality in World Health Organization (WHO) data for 34 low-mortality countries in 2000, demonstrating significant gradient increases for women (33/34 countries) and men (22/34), from a later age than previously reported, dividing the postmenopausal period into phases. "Break points" were identified as intersects of lines of best fit to these and the same approach was used in analysis of Human Mortality Database data for 19 countries. There has been an upward migration of about 10 years in female age at break point since 1850. Male data flipped from mortality acceleration to deceleration and back in the late 20th century with no apparent shift in break point. Altered age at mortality acceleration appears genuine, gender-specific, and internationally consistent. Its timing prompts the hypothesis that it may relate to falling fertility.

Publication metadata

Author(s): Milne EMG

Publication type: Article

Publication status: Published

Journal: Biogerontology

Year: 2007

Volume: 1100

Pages: 46-59

Print publication date: 01/01/2007

ISSN (print): 1389-5729

ISSN (electronic): 1573-6768

Publisher: Springer


DOI: 10.1196/annals.1395.004


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