Dr Ian Hardcastle Professor Nicola Curtin Justin John James Leahy Martin Stockley Emeritus Professor Bernard Golding et al. | Discovery of potent chromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK) using a small-molecule library approach | 2005 |
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Professor Roger Griffin Emeritus Professor Bernard Golding Sophie Guiard Dr Ian Hardcastle Justin John James Leahy et al. | Selective benzopyranone and pyrimido[2,1-alpha]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: Synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro | 2005 |
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Justin John James Leahy Emeritus Professor Bernard Golding Professor Roger Griffin Dr Ian Hardcastle Dr Laurent Rigoreau et al. | Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries | 2004 |
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Jonathan Hollick Emeritus Professor Bernard Golding Professor Roger Griffin Dr Ian Hardcastle Justin John James Leahy et al. | Application of combinatorial chemistry for the identification of pyran-4-one and thiopyran-4-one inhibitors of DNA-dependent protein kinase | 2002 |
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Professor Roger Griffin Dr Ian Hardcastle Dr Laurent Rigoreau Martin Stockley Justin John James Leahy et al. | Cassette dosing iv and ip of novel DNA dependent protein kinase inhibitors | 2002 |
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Professor Roger Griffin Dr Ian Hardcastle Dr Laurent Rigoreau Martin Stockley Justin John James Leahy et al. | High throughput pharmacokinetics of novel DNA-dependent protein kinase inhibitors | 2002 |
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