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Browsing publications by Dr Nick Watkins.

Newcastle AuthorsTitleYearFull text
Dr Nick Watkins
Association of snR190 snoRNA chaperone with early pre-60S particles is regulated by the RNA helicase Dbp7 in yeast2021
Dr Robert van Nues
Dr Claudia Schneider
Dr Nick Watkins
RNA helicase-mediated regulation of snoRNP dynamics on pre-ribosomes and rRNA 2'-O-methylation2021
Kate Sloan
Andy Knox
Dr Graeme Wells
Dr Claudia Schneider
Dr Nick Watkins
et al.
Interactions and activities of factors involved in the late stages of human 18S rRNA maturation2019
Dr Graeme Wells
Franziska Weichmann
Kate Sloan
David Colvin
Dr Nick Watkins
et al.
The ribosome biogenesis factor yUtp23/hUTP23 coordinates key interactions in the yeast and human pre-40S particle and hUTP23 contains an essential PIN domain2017
Dr Nick Watkins
Unusual C'/D' motifs enable box C/D snoRNPs to modify multiple sites in the same rRNA target region2017
Andria Pelava
Dr Claudia Schneider
Dr Nick Watkins
The importance of ribosome production, and the 5S RNP–MDM2 pathway, in health and disease2016
Dr Graeme Wells
Franziska Weichmann
David Colvin
Kate Sloan
Dr Nick Watkins
et al.
The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans2016
Dr Graeme Wells
Franziska Weichmann
David Colvin
Kate Sloan
Dr Nick Watkins
et al.
The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans (vol 44, pg 5399, 2016) [Corrigendum]2016
Eileen Leung
Dr Claudia Schneider
Fu Yan
Hatem Mohi El Din
Dr Victoria Doronina
et al.
Integrity of SRP RNA is ensured by La and the nuclear RNA quality control machinery2014
Katherine Sloan
Dr Nick Watkins
The association of late-acting snoRNPs with human pre-ribosomal complexes requires the RNA helicase DDX212014
Kate Sloan
Dr Claudia Schneider
Dr Nick Watkins
The roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA2014
Kate Sloan
Dr Nick Watkins
Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing2013
Kate Sloan
Dr Nick Watkins
The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress2013
Kate Sloan
Dr Claudia Schneider
Dr Nick Watkins
Comparison of the yeast and human nuclear exosome complexes2012
Dr Amy Erhorn
Andy Knox
Dr Nick Watkins
Nucleolar disruption leads to the spatial separation of key 18S rRNA processing factors2012
Dr Claudia Schneider
Dr Nick Watkins
Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits2012
Dr Nick Watkins
The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA2012
Andy Knox
Dr Kenneth McKeegan
Charles Debieux
Dr Hannah Richardson
Dr Nick Watkins
et al.
A weak C’ box renders U3 snoRNA levels dependent on hU3-55K binding2011
Dr Robert Van Nues
Kate Sloan
Matthew Chicken
Dr Nick Watkins
Box C/D snoRNP catalysed methylation is aided by additional pre-rRNA base-pairing2011
Dr Nick Watkins
Evolution of box C/D RNP structure and function2011
Dr Nick Watkins
The Spatial-Functional Coupling of Box C/D and C'/D' RNPs Is an Evolutionarily Conserved Feature of the Eukaryotic Box C/D snoRNP Nucleotide Modification Complex2011
Dr Nick Watkins
A novel Nop5-sRNA interaction that is required for efficient archaeal box C/D sRNP formation2010
Dr Paul Dean
Jonathan Scott
Andy Knox
Sabine Quitard
Dr Nick Watkins
et al.
The Enteropathogenic E. coli Effector EspF Targets and Disrupts the Nucleolus by a Process Regulated by Mitochondrial Dysfunction2010
Dr Amy Erhorn
Andy Knox
Dr Nick Watkins
A Novel Small-Subunit Processome Assembly Intermediate That Contains the U3 snoRNP, Nucleolin, RRP5, and DBP42009
Dr Kenneth McKeegan
Charles Debieux
Dr Nick Watkins
Evidence that the AAA+ Proteins TIP48 and TIP49 Bridge Interactions between 15.5K and the Related NOP56 and NOP58 Proteins during Box C/D snoRNP Biogenesis2009
Dr Claudia Schneider
Dr Nick Watkins
Minor spliceosome components are predominantly localized in the nucleus2008
Dr Kenneth McKeegan
Charles Debieux
Dr Nick Watkins
A dynamic scaffold of pre-snoRNP factors facilitates human box C/D snoRNP assembly2007
Dr Heather Lamb
Paul Thompson
Dr Nick Watkins
Professor Alastair Hawkins
Functional analysis of the GTPases EngA and YhbZ encoded by Salmonella typhimurium2007
Dr Nick Watkins
Involvement of nuclear import and export factors in U8 box C/D snoRNP biogenesis2007
Dr Nick Watkins
Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies2006
Dr Nick Watkins
Protein-protein and protein-RNA contacts both contribute to the 15.5K-mediated assembly of the U4/U6 snRNP and the box C/D snoRNPs2006
Dr Nick Watkins
Dr Claudia Schneider
Assembly and Maturation of the U3 snoRNP in the Nucleoplasm in a Large Dynamic Multiprotein Complex2004
Dr Nick Watkins
Role of pre-rRNA base pairing and 80S complex formation in subnucleolar localization of the U3 snoRNP2004
Dr Nick Watkins
Conserved Stem II of the Box C/D Motif Is Essential for Nucleolar Localization and Is Required, Along with the 15.5K Protein, for the Hierarchical Assembly of the Box C/D snoRNP2002
Dr Nick Watkins
The hU3-55K Protein Requires 15.5K Binding to the Box B/C Motif as Well as Flanking RNA Elements for Its Association with the U3 Small Nucleolar RNA in Vitro2002
Dr Nick Watkins
A common core RNP structure shared between the small nucleolar box C/D RNPs and the spliceosomal U4 snRNP2000