Publications by Professor Richard Edmondson - ePrints

Browsing publications by Professor Richard Edmondson.

Newcastle Authors	Title	Year
Dr Aiste McCormick Dr Peter Donoghue Michelle Dixon Dr Rachel O'Donnell James Murray et al.	Ovarian Cancers Harbour Defects in Non-Homologous End Joining Resulting in Resistance to Rucaparib	2017
Fiona Middleton Dr Miranda Patterson Dr Claire Elstob Dr Sarah Fordham Dr Ashleigh Herriott et al.	Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition	2015
Dr Aiste McCormick Dr Peter Donoghue Michelle Dixon Dr Rachel O'Donnell Dr Angelika Kaufmann et al.	Defects in non-homologous end joining pathway in ovarian cancers results in resistance to rucaparib	2015
Dr Rachel O'Donnell Dr Angelika Kaufmann Dr Aiste McCormick Professor Nicola Curtin Professor Richard Edmondson et al.	Intra- and inter-tumour heterogeneity in epithelial ovarian cancer: consequences for biomarker dependent stratification of therapies	2015
Dr Aiste McCormick Dr Rachel O'Donnell Dr Angelika Kaufmann Professor Richard Edmondson	Phosphatase and tensin homolog (PTEN) is a potential target for ovarian cancer sensitisation to cytotoxic agents	2015
Dr Aiste McCormick Michelle Dixon Dr Rachel O'Donnell Dr Angelika Kaufmann Professor Richard Edmondson et al.	PTEN function is important in determining ovarian cancer sensitivity to cytotoxic agents	2015
Dr Miranda Patterson Dr Ian Forrest Becci Sharrock Maria Lane Dr Angelika Kaufmann et al.	Assessing the function of homologous recombination DNA repair in malignant pleural effusion (MPE) samples	2014
Laura Woodhouse Dr Aiste McCormick Dr Rachel O'Donnell Dr Angelika Kaufmann Professor Richard Edmondson et al.	Development of a Functional Assay to Determine the Nucleotide Excision Repair Status of Epithelial Overian Cancer	2014
Dr Asima Mukhopadhyay Michelle Dixon Dr Evan Mulligan James Murray Professor Nicola Curtin et al.	Evaluation of different methods to assess homologous recombination status and sensitivity to parp inhibitors in ovarian cancer	2014
Dr Scott Wilkes Professor Richard Edmondson	What do we do with all the false-positive CA125s?	2013
Dr Ahmed Elattar Dr Asima Mukhopadhyay Dr Fadhel Shaheen Professor Ruth Plummer Professor Craig Robson et al.	Androgen receptor expression is a biological marker for androgen sensitivity in high grade serous epithelial ovarian cancer	2012
Dr Asima Mukhopadhyay Professor Ruth Plummer Dr Ahmed Elattar Dr San Soo Hoo Bisha Uzir et al.	Clinicopathological features of homologous recombination deficient epithelial ovarian cancers: Sensitivity to PARP inhibitors, platinum and survival	2012
Dr Asima Mukhopadhyay Professor Ruth Plummer Dr Ahmed Elattar Dr San Soo Hoo Bisha Uzir et al.	Clinicopathological features of homologous recombination deficient epithelial ovarian cancers: Sensitivity to PARP inhibitors, platinum and survival	2012
Dr Asima Mukhopadhyay Professor Ruth Plummer Dr Ahmed Elattar Dr San Soo Hoo Bisha Uzir et al.	Clinicopathological Features of Homologous Recombination-Deficient Epithelial Ovarian Cancers: Sensitivity to PARP Inhibitors, Platinum, and Survival	2012
Dr Aiste McCormick Dr Asima Mukhopadhyay Professor Ruth Plummer Professor Nicola Curtin Professor Richard Edmondson et al.	Defective homologous recombination in human cancers	2012
Amit Patel Professor Richard Edmondson Dr Ali Kucukmetin Dr Alberto Lopes	Intra-operative frozen section analysis for suspected early-stage ovarian cancer: 11 years of Gateshead Cancer Centre experience	2012
Dr Aiste McCormick Professor Nicola Curtin Professor Richard Edmondson	Non homologous end joining assessment in ovarian cancer	2012
Dr Emma Meczes Huw Thomas Professor Richard Edmondson Professor Gareth Veal Professor Alan Boddy et al.	Therapy induced carboplatin-DNA adduct levels in human ovarian tumours in relation to assessment of adduct measurement in mouse tumours	2012
Dr Amy Peasland Dr Tao Chen Professor Richard Edmondson Professor Nicola Curtin	Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines	2011
Dr Asima Mukhopadhyay Professor Nicola Curtin Professor Ruth Plummer Professor Richard Edmondson	PARP Inhibitors And Epithelial Ovarian Cancer: An Approach To Targeted Chemotherapy And Personalized Medicine	2011
Dr Katherine Sturgess Professor Mary Slatter Dr Venetia Bigley Professor Muzlifah Haniffa Dr Xiao Wang et al.	Reduced Intensity Hematopoietic Stem Cell Transplant Rescues Immune Function and Corrects Pulmonary Alveolar Proteinosis in DCML Deficiency/GATA 2 Mutation	2011
Professor Richard Edmondson	The Role of Hormonal therapy in Gynaecological Cancers – Current Status and Future Directions	2011
Dr Yvette Drew Dr Evan Mulligan Wan Vong Huw Thomas Suzanne Kyle et al.	Therapeutic Potential of Poly(ADP-ribose) Polymerase Inhibitor AG014699 in Human Cancers With Mutated or Methylated BRCA1 or BRCA2	2011
Professor Richard Edmondson Dr Steven Darby	Microcell mediated chromosome transfer identifies EPB41L3 as a functional suppressor of epithelial ovarian cancers	2010
Professor Craig Robson Professor Richard Edmondson	Anti androgen therapy in ovarian cancer: an overlooked treatment modality?	2010
Dr Asima Mukhopadhyay Dr Ahmed Elattar Dr Aiste McCormick Sarah Wilkinson Dr Yvette Drew et al.	Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly(ADP-ribose) polymerase inhibitors	2010
Professor Richard Edmondson Dr Diana Mansour	Liquid based cytology improves the positive predictive value of glandular smears compared to conventional cytology	2010
Professor Richard Edmondson	3β-Hydroxysteroid dehydrogenases and pre-receptor steroid metabolism in the human ovarian surface epithelium	2009
Dr Ali Kucukmetin Sarah Wilkinson Dr Ann Fisher Dr Ahmed Elattar Professor Craig Robson et al.	Androgen-related expression of G-proteins in ovarian cancer	2009
Dr Alberto Lopes Professor Richard Edmondson	Evaluation of prognostic factors and treatment outcomes in uterine carcinosarcoma	2009
Dr Alberto Lopes Professor Richard Edmondson	Lower limb lymphoedema and vulval cancer: feasibility of prophylactic compression garments & validation of leg volume measurement	2009
Professor Richard Edmondson	Recurrent cervical cancer presenting as malignant pericarditis: Case report and review of the literature	2009
Sarah Wilkinson Dr Ali Kucukmetin Dr Steven Darby Vincent Gnanapragasam Professor Alan Calvert et al.	Expression of gonadotrophin releasing hormone receptor I is a favorable prognostic factor in epithelial ovarian cancer	2008
Dr Yvette Drew Suzanne Kyle Professor Richard Edmondson Professor Ruth Plummer Professor Nicola Curtin et al.	Investigating DNA double strand break formation and repair in response to the PARP inhibitor AG014699 in cell lines defective in Homologous Recombination: a role for PARP inhibitors in sporadic cancers? [abstract]	2008
Professor Alan Calvert Professor Ruth Plummer Professor Nicola Curtin Professor Richard Edmondson Dr Yvette Drew et al.	PARP inhibitors in cancer treatment	2008
Professor Richard Edmondson	Cervical cancer in pregnancy: An assault on family and fertility	2007
Dr Steven Darby Dr Jacqueline Stockley Professor Richard Edmondson Professor Craig Robson Professor Hing Leung et al.	Expression of gonadotrophin releasing hormone type II in prostate cancer is androgen regulated	2007
Dr David Jamieson Kerrie Wilson Dr Simon Pridgeon Dr Jane Margetts Professor Richard Edmondson et al.	NAD(P)H:quinone oxidoreductase 1 and NRH:quinone oxidoreductase 2 activity and expression in bladder and ovarian cancer and lower NRH:quinone oxidoreductase 2 activity associated with an NQO2 exon 3 single-nucleotide polymorphism	2007
Raf Hussain Dr Alberto Lopes Professor Richard Edmondson	The feasibility of storing ovarian tumor cells on databasing paper: establishing a library of ovarian cancer DNA	2007
Professor Richard Edmondson John Monaghan Dr Barry Davies	Gonadotropins mediate DNA synthesis and protection from spontaneous cell death in human ovarian surface epithelium	2006
Professor Richard Edmondson	Guidelines for gynecological cancer-an audit of current network documents in England and Wales	2006
Islay Steele Professor Richard Edmondson Professor Hing Leung Dr Barry Davies	Ligands to FGF receptor 2-IIIb induce proliferation, motility, protection from cell death and cytoskeletal rearrangements in epithelial ovarian cancer cell lines	2006
Dr Alberto Lopes Professor Richard Edmondson	Risk adjusted surgical audit in gynaecological oncology: P-POSSUM does not predict outcome	2006
Dr Barry Davies Islay Steele Professor Richard Edmondson Dr Simon Zwolinski Dr Gabriele Saretzki et al.	Immortalisation of human ovarian surface epithelium with telomerase and temperature-senstitive SV40 large T antigen	2003
Professor Richard Edmondson John Monaghan Dr Barry Davies	The human ovarian surface epithelium is an androgen responsive tissue	2002
Professor Richard Edmondson John Monaghan Dr Barry Davies	Androgens have direct effects on human ovarian surface epithelium	2001
Professor Richard Edmondson John Monaghan	The epidemiology of ovarian cancer	2001
Professor Richard Edmondson	Staff changes will have affected ventouse rates	1999