Publications by Emeritus Professor Geoffrey Toms - ePrints

Browsing publications by Emeritus Professor Geoffrey Toms.

Newcastle Authors	Title	Year
Emeritus Professor Geoffrey Toms	GS-5806 Inhibits a Broad Range of Respiratory Syncytial Virus Clinical Isolates by Blocking the Virus-Cell Fusion Process	2016
Bo Hiriote Sarah Welsh Emeritus Professor Geoffrey Toms	An Investigation of the Genetic Basis of Increased Susceptibility to Neutralization by Anti-Fusion Glycoprotein Antibody Arising on Passage of Human Respiratory Syncytial Virus in Cell Culture	2015
Dr Simon Bridge Dr David Sheridan Dr Daniel Felmlee Fiona Fenwick Dr Clare Lanyon et al.	PCSK9, apolipoprotein E and lipoviral particles in chronic hepatitis C genotype 3: Evidence for genotype-specific regulation of lipoprotein metabolism	2015
Dr Cheng Siang Tan Fiona Fenwick Dr Edward Routledge Emeritus Professor Geoffrey Toms	Generation and epitope mapping of a sub-group cross-reactive anti-respiratory syncytial virus G glycoprotein monoclonal antibody which is protective in vivo	2014
Fiona Fenwick Emeritus Professor Geoffrey Toms	Imaging analysis of human metapneumovirus-infected cells provides evidence for the involvement of F-actin and the raft-lipid microdomains in virus morphogenesis	2014
Dr Alison Tedcastle Fiona Fenwick Emeritus Professor Geoffrey Toms	Immunogenicity in Mice of Human Metapneumovirus With a Truncated SH Glycoprotein	2014
Dr David Sheridan Dr Daniel Felmlee Dr Simon Bridge Fiona Fenwick Emeritus Professor Geoffrey Toms et al.	Metabolic Syndrome and Insulin Resistance are Associated with Maximum Hepatitis C Lipoviral Particles in Genotype 1 Infection	2013
Dr David Sheridan Dr Simon Bridge Dr Daniel Felmlee Emeritus Professor Geoffrey Toms Dr R Neely et al.	Apolipoprotein-E and hepatitis C lipoviral particles in genotype 1 infection: Evidence for an association with interferon sensitivity	2012
Alison Tedcastle Fiona Fenwick Ruth Ingram Mark Robinson Emeritus Professor Geoffrey Toms et al.	The characterization of monoclonal antibodies to human metapneumovirus and the detection of multiple forms of the virus nucleoprotein and phosphoprotein	2012
Dr Simon Bridge Dr David Sheridan Dr Daniel Felmlee Emeritus Professor Geoffrey Toms Professor Margaret Bassendine et al.	Apolipoprotein E and low-density, apolipoprotein B associated lipoviral particles in chronic Hepatitis C infection: Evidence for genotype-specific modulation of lipid pathways	2011
Professor Margaret Bassendine Dr David Sheridan Dr Daniel Felmlee Dr Simon Bridge Emeritus Professor Geoffrey Toms et al.	HCV and the hepatic lipid pathway as a potential treatment target	2011
Emeritus Professor Geoffrey Toms	Molecular Epidemiology and Evolution of Human Respiratory Syncytial Virus and Human Metapneumovirus	2011
Dr Daniel Felmlee Dr David Sheridan Dr Simon Bridge Emeritus Professor Geoffrey Toms Professor Margaret Bassendine et al.	Use of intralipid infusion to analyse apolipoprotein B (APOB) and HCV RNA kinetics in chronic infection	2011
Dr David Sheridan Professor Kim Bartlett Dr Daniel Felmlee Dr Simon Bridge Emeritus Professor Geoffrey Toms et al.	Hypocholesterolaemia in chronic hepatitis C genotype 3 infection is due to both reduced cholesterol production and increased LDL clearance	2010
Dr David Sheridan Professor Kim Bartlett Dr Daniel Felmlee Dr Simon Bridge Emeritus Professor Geoffrey Toms et al.	Hypocholesterolaemia in chronic Hepatitis C virus (HCV) infection - Reduced production or increased LDL clearance?	2010
Dr Simon Bridge Dr David Sheridan Dr Daniel Felmlee Dr Soren Nielsen Dr R Neely et al.	Insulin resistance and low-density apolipoprotein B-associated lipoviral particles in hepatitis C virus genotype 1 infection	2010
Dr Simon Bridge Dr David Sheridan Dr Daniel Felmlee Dr Soren Nielsen Dr R Neely et al.	Insulin resistance correlates with low density hepatitis C virus particles in genotype 1 infection	2010
Dr Daniel Felmlee Dr David Sheridan Dr Simon Bridge Dr Soren Nielsen Emeritus Professor Geoffrey Toms et al.	Intravascular Transfer Contributes to Postprandial Increase in Numbers of Very-Low-Density Hepatitis C Virus Particles	2010
Dr Simon Bridge Dr David Sheridan Dr Daniel Felmlee Emeritus Professor Geoffrey Toms Dr R Neely et al.	Low density Hepatitis C virus particles (lipoviral particles) associate with insulin resistance in genotype 1 infection	2010
Dr Simon Bridge Dr David Sheridan Dr Daniel Felmlee Emeritus Professor Geoffrey Toms Professor Margaret Bassendine et al.	Measurement of low-density Apolipoprotein B associated lipoviral particles in hepatitis C virus genotype 1 infection is more clinically relevant than total viral load	2010
Dr Daniel Felmlee Dr David Sheridan Dr Simon Bridge Emeritus Professor Geoffrey Toms Professor Margaret Bassendine et al.	The HCV life-cycle in the vascular compartment	2010
Dr Simon Bridge Dr David Sheridan Dr Daniel Felmlee Dr Soren Nielsen Emeritus Professor Geoffrey Toms et al.	Apolipoprotein B Associated Hepatitis C Virus (HCV): A Minority of Total Viral Load in Patients with Chronic HCV	2009
Dr David Sheridan Dr David Price Dr Matthias Schmid Emeritus Professor Geoffrey Toms Dr Peter Donaldson et al.	Apolipoprotein B-associated cholesterol is a determinant of treatment outcome in patients with chronic hepatitis C virus infection receiving anti-viral agents interferon-alpha and ribavirin	2009
Dr Daniel Felmlee Dr Simon Bridge Dr David Sheridan Dr Soren Nielsen Emeritus Professor Geoffrey Toms et al.	Large and Buoyant Hepatitis C Virus (HCV) Particles Surge after Patients Consume a High-Fat Meal	2009
Dr David Sheridan Dr David Price Dr Matthias Schmid Emeritus Professor Geoffrey Toms	Apolipoprotein B associated cholesterol level is a predictor of response to therapy in chronic hepatitis C	2008
Dr Soren Nielsen Siti Ibrahim Professor Margaret Bassendine Emeritus Professor Geoffrey Toms	Binding of liver derived, low density hepatitis C virus to human hepatoma cells	2008
Dr Soren Nielsen Professor Margaret Bassendine Caroline Martin Daniel Lowther Dr Paul Purcell et al.	Characterization of hepatitis C RNA-containing particles from human liver by density and size	2008
Fiona Fenwick Emeritus Professor Geoffrey Toms	Molecular epidemiology of human metapneumovirus in Ireland	2008
Christopher Mee Dr Soren Nielsen Emeritus Professor Geoffrey Toms	Protein kinase A-dependent step(s) in hepatitis C virus entry and infectivity	2008
Dr Soren Nielsen Dr Lynette Morgan Emeritus Professor Geoffrey Toms	Purification of human respiratory syncytial virus by ultracentrifugation in iodixanol density gradient	2008
Dr Soren Nielsen Professor Margaret Bassendine Emeritus Professor Geoffrey Toms	Characterization of hepatitis C RNA containing particles from human liver by density and morphology	2007
Dr Soren Nielsen Professor Margaret Bassendine Emeritus Professor Geoffrey Toms	Characterization of hepatitis C virus associated with very low density lipoprotein (VLDL) in infected human serum and liver	2007
Fiona Fenwick Martin Robinson Emeritus Professor Geoffrey Toms	Diagnosis of human metapneumovirus by immunofluorescence staining with monoclonal antibodies in the North-East of England	2007
Rachel Marsh Emeritus Professor Geoffrey Toms	Increased susceptibility of human respiratory syncytial virus to neutralization by anti-fusion protein antibodies on adaptation to replication in cell culture	2007
Dr David Price Professor Margaret Bassendine Emeritus Professor Geoffrey Toms Dr Matthias Schmid Dr Christopher Morris et al.	Apolipoprotein ε3 allele is associated with persistent hepatitis C virus infection	2006
Dr Soren Nielsen Professor Margaret Bassendine Professor Alastair Burt Caroline Martin Dr Wanna Pumeechockchai et al.	Association between hepatitis C virus and very-low-density lipoprotein (VLDL)/LDL analyzed in iodixanol density gradients	2006
Ruth Ingram Sarah Fenwick Emeritus Professor Geoffrey Toms	Detection of human metapneumovirus in respiratory secretions by reverse-transcriptase polymerase chain reaction, indirect immunofluorescence, and virus isolation in human bronchial epithelial cells	2006
Dr Soren Nielsen Professor Margaret Bassendine Caroline Martin Emeritus Professor Geoffrey Toms	Development of a purification procedure for native hepatitis C virus from human liver	2006
Emeritus Professor Geoffrey Toms Fiona Fenwick	Diagnosis of human metapneumovirus by immunofluorescence - the Newcastle experience	2006
Fiona Fenwick Professor Margaret Bassendine Dr Kaushik Agarwal Professor Debra Bevitt Dr Wanna Pumeechockchai et al.	Immunohistochemical assessment of hepatitis C virus antigen in cholestatic hepatitis after liver transplantation	2006
Dr Chantana Mekseepralard Emeritus Professor Geoffrey Toms Dr Edward Routledge	Protection of mice against Human respiratory syncytial virus by wild-type and aglycosyl mouse-human chimaeric lgG antibodies to subgroup-conserved epitopes on the G glycoprotein	2006
Emeritus Professor Geoffrey Toms Professor David Kavanagh	Acute respiratory infection in a renal transplant recipient	2005
Rachel Marsh Emeritus Professor Alan Craft Emeritus Professor Geoffrey Toms	Analysis of the binding of monoclonal and polyclonal antibodies to the glycoproteins of antigenic variants of human respiratory syncytial virus by surface plasmon resonance	2005
Caroline Martin Dr Soren Nielsen Professor Margaret Bassendine Emeritus Professor Geoffrey Toms	Hepatitis C virus lipo-viro-particle interactions with human hepatocytes and inhibition of of binding	2005
Dr Soren Nielsen Professor Alastair Burt Caroline Martin Professor Margaret Bassendine Emeritus Professor Geoffrey Toms et al.	Hepatitis C virus RNA circulates predominantly in VLDL-like lipo-viral particles	2005
Dr Soren Nielsen Professor Alastair Burt Caroline Martin Professor Margaret Bassendine Emeritus Professor Geoffrey Toms et al.	Human hepatitis C virus RNA circulates predominantly in VLDL-like lipo-viral-particles	2005
Dr Soren Nielsen Professor Margaret Bassendine Professor Alastair Burt Professor Debra Bevitt Emeritus Professor Geoffrey Toms et al.	Characterization of the genome and structural proteins of hepatitis C virus resolved from infected human liver	2004
Rachel Marsh Emeritus Professor Alan Craft Emeritus Professor Geoffrey Toms	Detection of human respiratory syncytial virus genotype specific antibody responses in infants	2004
Emeritus Professor Alan Craft Fiona Fenwick Emeritus Professor Geoffrey Toms	Measurement of antibody against contemporary virus lineages of human respiratory syncytial virus sub-group A in infants and their mothers	2004
Emeritus Professor Alan Craft Emeritus Professor Geoffrey Toms	Measurement of antibody against contemporary virus lineages of human respiratory syncytial virus sub-group A in infants and their mothers	2004
Fiona Fenwick Emeritus Professor Geoffrey Toms	Antibody response after RSV infection in children younger than 1 year of age living in a rural area of Mozambique	2003
Professor Alastair Burt Caroline Martin Professor Margaret Bassendine Emeritus Professor Geoffrey Toms	Association of HCV particles with LDL/VLDL: Analysis using isotonic iodixanol gradient centrifugation & real time PCR	2003
Dr Soren Nielsen Professor Margaret Bassendine Professor Alastair Burt Emeritus Professor Geoffrey Toms	Characterisation of the genome and structural proteins of beta-lipoprotein associated HCV extracted from infected human liver	2003
Dr Soren Nielsen Dr Wanna Pumeechockchai Professor Alastair Burt Professor Margaret Bassendine Emeritus Professor Geoffrey Toms et al.	Characterization of HCV RNA particles from the serum of a patient with common variable immunodeficiency on isotonic iodixanol (optiprep) gradients. Association with apolipoprotein-B100	2002
Dr Soren Nielsen Professor Margaret Bassendine Alison Burt Emeritus Professor Geoffrey Toms	Characterization of the structural proteins of HCV isolated from human liver	2002
Dr Wanna Pumeechockchai Professor Debra Bevitt Dr Kaushik Agarwal Professor Margaret Bassendine Emeritus Professor Geoffrey Toms et al.	Hepatitis C virus particles of different density in the blood of chronically infected immunocompetent and immunodeficient patients: Implications for virus clearance by antibody	2002
Fiona Fenwick Emeritus Professor Geoffrey Toms	Prevalence of respiratory syncytial virus IgG antibodies in infants living in a rural area of Mozambique	2002
Professor Debra Bevitt Emeritus Professor Geoffrey Toms	Comparison of human respiratory syncytial virus A2 and 8/60 fusion glycoprotein gene sequences and mapping of sub-group specific antibody epitopes	2001
Dr Margaret Jackson Professor Debra Bevitt Emeritus Professor Geoffrey Toms Professor Margaret Bassendine	Comparison of cytotoxic T-lymphocyte responses to hepatitis C virus core protein in uninfected and infected individuals	1999
Professor Debra Bevitt Emeritus Professor Geoffrey Toms Professor Thomas Lennard Professor Bruce Westley Dr Brian Angus et al.	New monoclonal antibodies to oestrogen and progesterone receptors effective for paraffin section immunohistochemistry	1997
Professor Debra Bevitt Dr Gavin Spickett Emeritus Professor Geoffrey Toms Professor Margaret Bassendine	Hepatitis C virus density heterogeneity and viral titre in acute and chronic infection: A comparison of immunodeficient and immunocompetent patients	1996
Dr Jennifer Kernahan Dr Ronald Scott Emeritus Professor Alan Craft Emeritus Professor Geoffrey Toms	T cell function in children with acute lymphoblastic leukemia	1993
Dr John Anderson Emeritus Professor Geoffrey Toms Dr Ronald Scott	Recognition of respiratory syncytial (RS) virus proteins by human and BALB/C CD4+ lymphocytes	1991
Dr John Anderson Jean Norden Dr David Saunders Emeritus Professor Geoffrey Toms Dr Ronald Scott et al.	Analysis of the local and systemic immune responses induced in BALB/c mice by experimental respiratory syncytial virus infection	1990
Emeritus Professor Alan Craft Dr Jennifer Kernahan Dr Michael Reid Dr Ronald Scott Emeritus Professor Geoffrey Toms et al.	Local antibody production and respiratory syncytial virus infection in children with leukaemia	1990
Dr John Anderson Emeritus Professor Geoffrey Toms Dr Ronald Scott	Natural killer cell response to respiratory syncytial virus in the Balb/c mouse model	1989
Dr Edward Routledge Dr Tony Samson Dr Ronald Scott Dr John Anderson Emeritus Professor Geoffrey Toms et al.	The purification of four respiratory syncytial virus proteins and their evaluation as protective agents against experimental infection in BALB/c mice	1988
Emeritus Professor Alan Craft Dr Jennifer Kernahan Dr Michael Reid Emeritus Professor Geoffrey Toms	Virus infections in childhood malignant disease	1987
Professor Anne Dickinson Dr Jennifer Kernahan Dr Michael Reid Professor Stephen Proctor Emeritus Professor Geoffrey Toms et al.	Interferon responses of peripheral blood mononuclear cells from normal and leukaemic children	1986
Claire Taylor Emeritus Professor Alan Craft Dr Jennifer Kernahan Dr Michael Reid Emeritus Professor Geoffrey Toms et al.	Nasal interferon responses in leukaemia	1985
Emeritus Professor Geoffrey Toms	Haemadsorption-negative assay of rubella virus in baby hamster kidney cells	1973
Emeritus Professor Geoffrey Toms	Replication of influenza virus in organ cultures of human endometrium	1973
Emeritus Professor Geoffrey Toms	The use of rivanol for the removal of nonspecific inhibitors of rubella virus haemagglutinin	1973