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Browsing publications by Professor Dianne Ford.

Newcastle AuthorsTitleYearFull text
Dr Nicola Simcock
Dr Luisa Wakeling
Professor Dianne Ford
Professor Geraldine Wright
Effects of age and nutritional state on the expression of gustatory receptors in the honeybee (Apis mellifera)2017
Dr Jill McKay
Dr Long Xie
Professor Dianne Ford
Professor John Mathers
Maternal folate depletion during early development and high fat feeding from weaning elicit similar changes in gene expression, but not in DNA methylation, in adult offspring2017
Sadat Aziz
Dr Luisa Wakeling
Dr Satomi Miwa
Goiuri Alberdi Aresti
Professor John Hesketh
et al.
Metabolic programming of a beige adipocyte phenotype by genistein2017
Professor Dianne Ford
Epigenetic Responses to Diet in Aging2016
Dr Jill McKay
Professor Dianne Ford
Professor John Mathers
Gene promoter DNA methylation patterns have a limited role in orchestrating transcriptional changes in the fetal liver in response to maternal folate depletion during pregnancy.2016
Dr Jill McKay
Dr Long Xie
Professor Dianne Ford
Professor John Mathers
Organ-specific gene expression changes in the fetal liver and placenta in response to maternal folate depletion2016
Dr Joy Hardyman-Carlile
Dr John Tyson
Dr Kelly Jackson
Christine Aldridge
Dr Simon Cockell
et al.
Zinc sensing by metal-responsive transcription factor 1 (MTF1) controls metallothionein and ZnT1 expression to buffer the sensitivity of the transcriptome response to zinc2016
Dr Jill McKay
Professor Dianne Ford
Altered expression of two zinc transporters, SLC30A5 and SLC30A6, underlies a mammary gland disorder of reduced zinc secretion into milk2015
Hadeil Alsufiani
Professor Dianne Ford
Professor John Mathers
Dietary Intakes of Zinc and Its Absorption Modifiers in Young and Older Saudi Adults2015
Sadat Aziz
Dr Satomi Miwa
Professor John Hesketh
Professor Dianne Ford
Induction by genistein of a gene expression profile in mouse NIH3T3-L1 cells indicating conversion of white to beige adipocytes2015
Professor Dianne Ford
Seashells by the zinc shore: a meeting report of the International Society for Zinc Biology, Asilomar, CA 20142015
Dr Luisa Wakeling
Laura Ions
Suzie Escolme
Dr Simon Cockell
Tianhong Su
et al.
SIRI1 effects DNA methylation of polycomb protein target genes, a hotspot of the epigenetic shift observed in ageing2015
Hadeil Alsufiani
Professor Dianne Ford
Professor John Mathers
The relative validity and repeatability of an FFQ for estimating intake of zinc and its absorption modifiers in young and older Saudi adults2015
Ogo Ogo
Dr John Tyson
Dr Simon Cockell
Dr Alison Howard
Dr Ruth Valentine
et al.
The zinc finger protein ZNF658 regulates the transcription of genes involved in zinc homeostasis and affects ribosome biogenesis through the zinc transcriptional regulatory element (ZTRE)2015
Sadat Aziz
Dr Luisa Wakeling
Professor John Hesketh
Professor Dianne Ford
Genistein promotes a gene expression profile characteristic of brown rather than white adipocytes and increases Sirt1 expression in mouse NIH3T3-L1 cells2014
Dr Jill McKay
Dr Long Xie
Caroline Manus
Dr Sabine Langie
Dr Ross Maxwell
et al.
Metabolic effects of a high-fat diet post-weaning after low maternal dietary folate during pregnancy and lactation2014
Dr Pier Paoli
Dr Luisa Wakeling
Professor Geraldine Wright
Professor Dianne Ford
The dietary proportion of essential amino acids and Sir2 influence lifespan in the honeybee2014
Dr Helen Bosomworth
Professor Dianne Ford
Dr Ruth Valentine
Altered Expression of ZnT10 in Alzheimer's Disease Brain2013
Joy Hardyman
Ogo Ogo
Dr John Tyson
Dr Luisa Wakeling
Dr Ruth Valentine
et al.
DNA methylation of the zinc transcriptional regulatory element and its potential contribution to zinc dyshomeostasis in ageing2013
Dr Jill McKay
Dr Long Xie
Professor Dianne Ford
Professor John Mathers
Effects of folate depletion in utero and a high fat diet post-weaning on DNA methylation in the adult mouse small intestine2013
Goiuri Alberdi Aresti
Dr Luisa Wakeling
Professor Dianne Ford
Effects of resveratrol on the methylation of lipogenic enzyme genes in 3T3-L1 adipocytes2013
Laura Ions
Dr Luisa Wakeling
Dr Helen Bosomworth
Joy Hardyman
Suzanne Hutchinson
et al.
Effects of Sirt1 on DNA methylation and expression of genes affected by dietary restriction2013
Professor Dianne Ford
Honeybees and cell lines as models of DNA methylation and aging in response to diet2013
Dr Jill McKay
Dr Alexandra Groom
Professor Dianne Ford
Lisa Coneyworth
Professor John Mathers
et al.
Influence of DNMT Genotype on Global and Site Specific DNA Methylation Patterns in Neonates and Pregnant Women2013
Professor Mark Walker
Professor Dianne Ford
Dr Ruth Valentine
Nutrigenetics and Nutrigenomics; the role of nutrition in gene expression2013
Anna Maciel Dominguez
Dr Daniel Swan
Professor Dianne Ford
Professor John Hesketh
Selenium alters miRNA profile in an intestinal cell line: Evidence that miR-185 regulates expression of GPX2 and SEPSH22013
Dr Helen Bosomworth
Dr Jared Thornton
Lisa Coneyworth
Professor Dianne Ford
Dr Ruth Valentine
et al.
Efflux function, tissue-specific expression and intracellular trafficking of the Zn transporter ZnT10 indicate roles in adult Zn homeostasis2012
Dr Jill McKay
Dr Alexandra Groom
Dr Kate Potter
Lisa Coneyworth
Professor Dianne Ford
et al.
Genetic and Non-Genetic Influences during Pregnancy on Infant Global and Site Specific DNA Methylation: Role for Folate Gene Variants and Vitamin B122012
Lisa Coneyworth
Dr Kelly Jackson
Dr John Tyson
Dr Helen Bosomworth
Eline van der Hagen
et al.
Identification of the human zinc transcriptional regulatory element (ZTRE): a palindromic protein-binding DNA sequence responsible for zinc-induced transcriptional repression2012
Dr Luisa Wakeling
Professor Dianne Ford
Polymorphisms in genes involved in the metabolism and transport of soy isoflavones affect the urinary metabolite profile in premenopausal women following consumption of a commercial soy supplement as a single bolus dose2012
Dr Luisa Wakeling
Professor John Hesketh
Professor Dianne Ford
SIRT1-independent epigenetic effects of resveratrol mediated through the estrogen receptor2012
Dr Luisa Wakeling
Fatema AlAtawi
Laura Ions
Professor John Hesketh
Professor Dianne Ford
et al.
SIRT1-independent epigenetic effects of resveratrol mediated through the estrogen receptor2012
Dr Jill McKay
Dr Long Xie
Dr Simon Harris
Professor Dianne Ford
Professor John Mathers
et al.
Blood as a surrogate marker for tissue-specific DNA methylation and changes due to folate depletion in post-partum female mice2011
Dr Jill McKay
Dr Long Xie
Caroline Manus
Professor Dianne Ford
Professor John Mathers
et al.
Consequences of Folate Depletion during Development and High Fat Intake from Weaning on Adiposity, Gene Expression and DNA Methylation in Adult Mice2011
Dr Jill McKay
Professor Dianne Ford
Professor Caroline Relton
Professor John Mathers
Consequences of Folate Depletion during Development for DNA Methylation and Gene Expression in the Fetal Mouse2011
Dr Jared Thornton
Professor Dianne Ford
Dr Ruth Valentine
Differential Subcellular Localization of the Splice Variants of the Zinc Transporter ZnT5 Is Dictated by the Different C-Terminal Regions2011
Dr Jill McKay
Dr Long Xie
Professor Caroline Relton
Professor Dianne Ford
Professor John Mathers
et al.
Folate Depletion during Development Causes Gene Expression Changes in Fetal and Adult Mouse Liver2011
Dr Jill McKay
Professor Caroline Relton
Professor Dianne Ford
Professor John Mathers
Maternal folate supply and sex influence gene-specific DNA methylation in the fetal gut2011
Professor Dianne Ford
Professor John Hesketh
Selenium in Human Health and Disease2011
Professor Dianne Ford
Dr Luisa Wakeling
The potential role of epigenetic responses to diet in ageing2011
Dr Alison Howard
Sajid Javed
Sarah Waring
Professor Dianne Ford
Emeritus Professor Barry Hirst
et al.
Glycine transporter GLYT1 is essential for glycine-mediated protection human intestinal epithelial cells against oxidative damage2010
Gemma Davison
Professor John Mathers
Professor Dianne Ford
Dr Ruth Valentine
[Meeting Abstract] Effects of Dietary Zinc Supply During Pregnancy on Global DNA Methylation2009
Laura Ions
Dr Luisa Wakeling
Professor Dianne Ford
Can soyabean isoflavones mimic the effects of energy restriction on healthy ageing?2009
Dr Luisa Wakeling
Laura Ions
Professor Dianne Ford
Could Sirt1-mediated epigenetic effects contribute to the longevity response to dietary restriction and be mimicked by other dietary interventions?2009
Lisa Coneyworth
Professor John Mathers
Professor Dianne Ford
Does promoter methylation of the SLC30A5 (ZnT5) zinc transporter gene contribute to the ageing-related decline in zinc status?2009
Lisa Coneyworth
Professor John Mathers
Professor Dianne Ford
Does promoter methylation of the SLC30A5 (ZnT5) zinc transporter gene contribute to the ageing-related decline in zinc status?2009
Dr Kevin Waldron
Dr Julian Rutherford
Professor Dianne Ford
Professor Nigel Robinson
Metalloproteins and metal sensing2009
Dr Jill McKay
Professor Dianne Ford
Professor Caroline Relton
Professor John Mathers
Bioinformatic interrogation of expression array data to identify nutritionally regulated genes potentially modulated by DNA methylation2008
Professor Dianne Ford
Does ageing affect zinc homeostasis and dietary requirements?2008
Louise Pritchett
Dr Kathryn Atherton
Dr Elaine Mutch
Professor Dianne Ford
Glucuronidation of the soyabean isoflavones genistein and daidzein by human liver is related to levels of UGT1A1 and UGT1A9 activity and alters isoflavone response in the MCF-7 human breast cancer cell line2008
Professor Dianne Ford
Intracellular zinc homeostasis in leukocyte subsets is regulated by different expression of zinc exporters ZnT-1 to ZnT-92008
Dr Kelly Jackson
Dr Ruth Valentine
Lisa Coneyworth
Professor John Mathers
Professor Dianne Ford
et al.
Mechanisms of mammalian zinc-regulated gene expression2008
Christopher Pedder
Professor Dianne Ford
Professor John Hesketh
Targeting of transcripts encoding membrane proteins in polarized epithelia: RNA-protein binding studies of the SGLT1 3′-UTR2008
Dr Jill McKay
Professor Caroline Relton
Professor Dianne Ford
Professor John Mathers
Effects of dietary zinc supply during pregnancy on foetal liver DNA methylation of the insulin-like growth factor 2 (Igf2) gene in C57BL/J6 mice2007
Dr Luisa Wakeling
Professor Dianne Ford
Genetic influences on interindividual variability in soybean isoflavone absorption and metabolism2007
Professor Caroline Relton
Dr Alexandra Groom
Dr Jill McKay
Professor Dianne Ford
Professor John Mathers
et al.
Polymorphic variation in DNA methyltransferase genes in relation to birth weight, smoking and folate status2007
Dr Kelly Jackson
Dr Jill McKay
Professor John Mathers
Professor Dianne Ford
Splice variants of the human zinc transporter ZnT5 (SLC30A5) are differentially localized and regulated by zinc through transcription and mRNA stability2007
Dr Jill McKay
Dr Kelly Jackson
Professor John Mathers
Professor Dianne Ford
Zinc Transporters in the Mouse Placenta Show a Coordinated Regulatory Response to Changes in Dietary Zinc Intake2007
Dr Ruth Valentine
Dr Kelly Jackson
Dr Graham Christie
Professor John Mathers
Professor Dianne Ford
et al.
ZnT5 variant B is a bidirectional zinc transporter and mediates zinc uptake in human intestinal Caco-2 cells2007
Dr Jill McKay
Rachel Russi
Professor John Mathers
Professor Dianne Ford
Effects of dietary zinc during pregnancy upon placental insulin-like growth factor 2 mRNA expression in C57BL/J6 mice2006
Dr Ruth Valentine
Professor John Mathers
Professor Dianne Ford
Intracellular trafficking and functional activity of splice variants of the zinc transporter SLC30A5.2006
Dr Kathryn Atherton
Dr Elaine Mutch
Professor Dianne Ford
Metabolism of the soyabean isoflavone daidzein by CYP1A2 and the extra-hepatic CYPs 1A1 and 1B1 affects biological activity2006
Dr Luisa Wakeling
Professor Dianne Ford
The association of single nucleotide polymorphisms with beta-glucosidase activity in oral epithelium2006
Dr Ruth Valentine
Professor Dianne Ford
Epithelial transport mechanisms involved in zinc nutrition2005
Dr Ruth Valentine
Sion Phillips
Judith Piper
Jagnohan Varma
Professor Frederick Campbell
et al.
Homeostatic regulation of zinc transporters in the human small intestine by dietary zinc supplementation2005
Annie Parry
Dr Michael Tilby
Professor Dianne Ford
Emerita Professor Suzanne Cholerton
Professor Andrew Pearson
et al.
Pharmacokinetics and metabolism of ifosfamide in relation to DNA damage assessed by the COMET assay in children with cancer2005
Imran Tahir
Dr Alison Howard
Professor Dianne Ford
Emeritus Professor Barry Hirst
Role of glycine pre-treatment and transport in intestinal cell protection2005
Dr Alison Howard
Professor Dianne Ford
Emeritus Professor Barry Hirst
Increased expression of specific intestinal amino acid and peptide transporter mRNA in rats fed by TPN is reversed by GLP-22004
Professor Dianne Ford
Intestinal and placental zinc transport pathways2004
Professor Dianne Ford
Emeritus Professor Barry Hirst
P-glycoprotein potentiates CYP3A4-mediated drug disappearance during Caco-2 intestinal secretory detoxification2004
Professor Dianne Ford
Emeritus Professor Barry Hirst
Expression of the peptide transporter hPepT1 in human colon: A potential route for colonic protein nitrogen and drug absorption2003
Dr Ruth Valentine
Dr Graham Christie
Sion Phillips
Rachel Russi
Professor John Mathers
et al.
A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane2002
Dr Graham Christie
Emeritus Professor Paul Taylor
Professor Dianne Ford
Cloning and intestinal localisation of hZTL1, a novel zinc transporter2002
Dr Valerie Wilson
Dr Alison Howard
Professor Dianne Ford
Emeritus Professor Barry Hirst
EGF enhanced transcription of the amino acid transporter hATB(0) in COS-7 cells2002
Professor Dianne Ford
Mechanistic explanations for the chemopreventive action of soyabean isoflavones: Reducing the possibilities2002
Sion Phillips
Rachel Russi
Professor John Mathers
Professor Dianne Ford
The effect of zinc on expression of the novel zinc transporter hZTL1 in human intestinal and placental cell lines2002
Dr Graham Christie
Professor Dianne Ford
Dr Alison Howard
Dr Ann Clark
Emeritus Professor Barry Hirst
et al.
Glycine supply to human enterocytes mediated by high-affinity basolateral GLYT12001
Lauretta Chan
Adele Dudley
Professor Dianne Ford
Emeritus Professor Barry Hirst
Interactions of testosterone with cytochrome P450 3A4 and P-glycoprotein in human intestinal Caco-2 cells2001
Dr Alison Howard
Emeritus Professor Andrew Rugg-Gunn
Professor Dianne Ford
Emeritus Professor Barry Hirst
Regional differences in small intestinal nutrient transporter transcript expression during total parenteral nutrition.2001
Professor Dianne Ford
Emeritus Professor Barry Hirst
System ASC activity and expression of the amino acid transporter ASCT1 in human intestinal Caco-2 cells2000
Dr Caroline Matthews
Professor Dianne Ford
Emeritus Professor Barry Hirst
Expression of GLYT1 in human endometrial epithelium1999
Professor David Thwaites
Professor Dianne Ford
Dr Michael Glanville
Professor Nicholas Simmons
H+/solute-induced intracellular acidification leads to selective activation of apical Na+/H+ exchange in human intestinal epithelial cells1999
Professor Dianne Ford
Professor David Thwaites
Professor Nicholas Simmons
Emeritus Professor Harry Gilbert
Emeritus Professor Barry Hirst
et al.
Substrate upregulation of the human small intestinal peptide transporter, hPepT11998