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Comparison of Mitochondrial Mutation Spectra in Ageing Human Colonic Epithelium and Disease: Absence of Evidence for Purifying Selection in Somatic Mitochondrial DNA Point Mutations

Lookup NU author(s): Professor Laura GreavesORCiD, Dr Joanna ElsonORCiD, Dr John Grady, Geoffrey Taylor, Professor Robert TaylorORCiD, Professor John MathersORCiD, Emeritus Professor Thomas Kirkwood, Emeritus Professor Doug Turnbull

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Publication metadata

Author(s): Greaves LC, Elson JL, Nooteboom M, Grady JP, Taylor GA, Taylor RW, Mathers JC, Kirkwood TBL, Turnbull DM

Publication type: Article

Publication status: Published

Journal: PLoS Genetics

Year: 2012

Volume: 8

Issue: 11

Print publication date: 15/11/2012

Date deposited: 23/11/2012

ISSN (electronic): 1553-7390

Publisher: Public Library of Science

URL: http://dx.doi.org/10.1371/journal.pgen.1003082

DOI: 10.1371/journal.pgen.1003082

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Funding

Funder referenceFunder name
BBSRC
EPSRC
Newcastle University Centre for Brain Ageing and Vitality
ESRC
906919Wellcome Trust Centre for Mitochondrial Research
G0700718MRC as part of the cross-Council Lifelong Health and Wellbeing Initiative
N12015Food Standards Agency

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